A lysine-restricted diet ameliorates obesity via enrichment of Parabacteroides goldsteinii and 1,4-methylimidazoleacetic acid by Chengzhi Chen (19567437)

“…Metabolomics revealed that P. goldsteinii increases 1,4-methylimidazoleacetic acid (MIAA), a metabolite linked to decreased body weight in animal models. …”

Image_8_Photodynamic Antifungal Activity of Hypocrellin A Against Candida albicans.TIF by Yijia Yang (6173015)

“…In this study, HA-mediated cytotoxicity in Candida albicans cells was evaluated after antimicrobial photodynamic therapy (aPDT). The results showed that 1.0 μg/ml HA significantly decreased the survival rate of C. albicans cells with light illumination. …”

Image_10_Photodynamic Antifungal Activity of Hypocrellin A Against Candida albicans.JPEG by Yijia Yang (6173015)

“…In this study, HA-mediated cytotoxicity in Candida albicans cells was evaluated after antimicrobial photodynamic therapy (aPDT). The results showed that 1.0 μg/ml HA significantly decreased the survival rate of C. albicans cells with light illumination. …”

Image_14_Photodynamic Antifungal Activity of Hypocrellin A Against Candida albicans.TIF by Yijia Yang (6173015)

“…In this study, HA-mediated cytotoxicity in Candida albicans cells was evaluated after antimicrobial photodynamic therapy (aPDT). The results showed that 1.0 μg/ml HA significantly decreased the survival rate of C. albicans cells with light illumination. …”

Image_9_Photodynamic Antifungal Activity of Hypocrellin A Against Candida albicans.JPEG by Yijia Yang (6173015)

“…In this study, HA-mediated cytotoxicity in Candida albicans cells was evaluated after antimicrobial photodynamic therapy (aPDT). The results showed that 1.0 μg/ml HA significantly decreased the survival rate of C. albicans cells with light illumination. …”

Knocking down both HIF-1α and HIF-2α attenuated c-Myc degradation by Ni ions and hypoxia in A549 cells. by Qin Li (36669)

“…(B) 100 µM DFO, 1 mM DMOG, and hypoxia (1% O₂) decreased c-Myc protein levels in A549 cells in a time-dependent manner. …”

<i>H. procumbens</i> root extract does not internalize the GHS-R1a receptor. by Cristina Torres-Fuentes (605288)

“…<p>Hek cells stably expressing the GHS-R1a receptor as a C-terminal EGFP fusion protein were visualized using the IN Cell Analyser 1000 (GE Healthcare) following different treatments: untreated (<b>A</b>), ghrelin (<b>B</b>,<b>C</b>), [D-Arg1, D-Phe5, D-Trp7,9, Leu11]-substance P (SP-analogue) (<b>D</b>), (Dlys³)-GHRP-6 (<b>E</b>) and <i>H. procumbens</i> root extract (<b>F</b>) at the indicated concentrations for 1 h at 37°C. …”

Myb-Binding Protein 1A (MYBBP1A) Is Essential for Early Embryonic Development, Controls Cell Cycle and Mitosis, and Acts as a Tumor Suppressor by Silvia Mori (129700)

“…In cell culture, down-regulation of MYBBP1A decreases the growth rate of wild type mouse embryonic stem cells, mouse embryo fibroblasts (MEFs) and of human HeLa cells, where it also promotes apoptosis. …”

Plasma miR-92a expression level and ROC curve in patients with non-Hodgkin's lymphoma by quantitative real-time PCR. by Kazuma Ohyashiki (229098)

“…<p>(A) Plasma miR-17-92a expression levels in normal subjects (open bars: Normal: n = 5) and diffuse large B-cell lymphoma (solid bars: DLBCL: n = 13), indicating that all of these miR-17-92a polycistronic miRs were remarkably decreased in plasma obtained from DLBCL patients. …”

The raw data of the paper with the title of " The Protective Effect of Schisandrin C against Methicillin-Resistant Staphylococcus aureus - Induced Otitis Media " by Weifang Sun (22459180)

“…<p dir="ltr"><a href="" target="_blank">Methicillin-resistant <i>Staphylococcus aureus</i> (MRSA) is a significant pathogen in </a><a href="" target="_blank">otitis media</a> (OM), including acute otitis media (AOM) and chronic suppurative otitis media (CSOM), presenting considerable therapeutic challenges due to its biofilm formation, host immune evasion and promotion of persistent inflammation. …”

Expression profiling in APP23 mouse brain: inhibition of Aβ amyloidosis and inflammation in response to LXR agonist treatment-4 by Iliya Lefterov (73826)

“…Note that T0 decreases iNOS even bellow its basal level if applied with Aβ (in , veh versus Aβ+T0, p < 0.01). …”

MicroRNA-181a Suppresses Mouse Granulosa Cell Proliferation by Targeting Activin Receptor IIA by Qun Zhang (155121)

“…Interestingly, we found that miR-181a expression decreased in ovaries of mice at age of 8, 12, and 21 days, as compared with that in ovaries of 3-day old mice, and its level was reduced in preantral and antral follicles of mice compared with that in primary ones. …”

Table 1_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.docx by Yingchao Wu (2870927)

“…Here, we highlight Saikosaponin A (SSA), a promising natural metabolite characterized by low toxicity, demonstrating significant efficacy against breast cancer through the induction of cellular senescence.…”

Expression of cell cycle-regulatory genes in MS4a4B-LV-infected EL4 cells. by Hui Xu (9203)

“…<p><b>A,</b> Total RNA was isolated from MS4a4B-LV vector- or mock LV vector-infected EL4 cells. …”

Data Sheet 1_Landscape analysis of m6A modification regulators reveals LRPPRC as a key modulator in tubule cells for DKD: a multi-omics study.docx by Li Jiang (120930)

“…Background<p>Diabetic Kidney Disease (DKD) is a serious complication of diabetes, imposing a substantial medical burden. …”

Data Sheet 1_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.docx by Yingchao Wu (2870927)

“…Here, we highlight Saikosaponin A (SSA), a promising natural metabolite characterized by low toxicity, demonstrating significant efficacy against breast cancer through the induction of cellular senescence.…”

Data Sheet 4_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.pdf by Yingchao Wu (2870927)

“…Here, we highlight Saikosaponin A (SSA), a promising natural metabolite characterized by low toxicity, demonstrating significant efficacy against breast cancer through the induction of cellular senescence.…”

Table 3_Multi-omics reveals that NOTCH1 promotes cervical cancer progression and reduces radiosensitivity.xlsx by Aihua Guo (13267712)

“…</p>Conclusions<p>This study clarifies NOTCH1’s role in promoting cervical cancer progression and reducing radiosensitivity, with has-miR-449a as a negative regulator, providing targets for optimizing cervical cancer radiotherapy.…”

Table 1_Multi-omics reveals that NOTCH1 promotes cervical cancer progression and reduces radiosensitivity.docx by Aihua Guo (13267712)

“…</p>Conclusions<p>This study clarifies NOTCH1’s role in promoting cervical cancer progression and reducing radiosensitivity, with has-miR-449a as a negative regulator, providing targets for optimizing cervical cancer radiotherapy.…”

The impact of socioeconomic status on the utilization of total hip arthroplasty during 1995–2017: 104,055 THA cases and 520,275 population controls from national databases in Denma... by Nina M Edwards (9567542)

“…For those on lowest income there was a higher risk of THA in 1995–2000 (aOR 1.2 [1.1–1.3]), changing to lower risk in 2013–2017 (aOR 0.8 [0.8–0.9]).…”