Viral ORF57 inhibits eIF2α phosphorylation. by Nishi R. Sharma (4543936)

“…<p>(A) Schematic diagrams showing the governing process of SG formation and the possible mechanism by which ORF57 may prevent it. …”

Table_1_Impact of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers on the Inflammatory Response and Viral Clearance in COVID-19 Patients.docx by Linna Huang (3837052)

“…</p><p>Methods: We included 229 patients with confirmed COVID-19 in a multicenter, retrospective cohort study. Propensity score matching at a ratio of 1:3 was introduced to eliminate potential confounders. …”

Supplementary file 2_Histopathological examination and transcriptomic profiling reveal gossypol toxicity-responsive genes related to fertility in mice.docx by Teame Gereziher Mehari (11253141)

“…Introduction<p>Gossypol impairs reproduction in both sexes, inducing mitochondrial dysfunction, irregular cycles, and fewer ovarian follicles, leading to decreased fertility rates. The present investigation was undertaken to evaluate the toxicological effects of (+)-gossypol powder, a substance derived from cottonseed in mice.…”

S1 Data - by Syed Salman Shahid (16625097)

“…<div><p>Methadone-based treatment for pregnant women with opioid use disorder is quite prevalent in the clinical environment. A number of clinical and animal model-based studies have reported cognitive deficits in infants prenatally exposed to methadone-based opioid treatments. …”

Table_6_Gene Co-expression Network Reveals Potential New Genes Related to Sugarcane Bagasse Degradation in Trichoderma reesei RUT-30.XLSX by Gustavo Pagotto Borin (751443)

“…Our results demonstrate a vast range of new promising targets that merit additional studies to improve the cellulolytic potential of T. reesei strains and to decrease the production costs of 2G ethanol.…”

Summary of the results identified in this manuscript through which NF-κB2 and RelB regulate p53 dependent cellular senescence in primary human NHD fibroblasts. by Alessio Iannetti (634715)

“…<p>Depletion of NF-κB2 and RelB leads to a decrease in Rb phosphorylation. Unphosphorylated Rb represses E2F transcriptional activity and consequently inhibits EZH2 expression (which is negatively regulated by p53). …”

Image1_Modified Baihu decoction therapeutically remodels gut microbiota to inhibit acute gouty arthritis.PNG by Xianyang Wang (2349529)

“…While the relative abundance of Lactobacillaceae, Erysipelotrichaceae, Ruminococcaceae, Prevotellaceae and Enterobacteriaceae showed a relative decrease in species abundance. Of these, the reduction in species abundance of Enterobacteriaceae was associated with a reduction in amino acid metabolism and environmental perception. …”

Data_Sheet_1_Global, regional, and national burden and attributable risk factors of neurological disorders: The Global Burden of Disease study 1990–2019.docx by Chenyu Ding (8203221)

“…From 1990 to 2019, the DALYs of neurological diseases belonging to the communicable, maternal, neonatal and nutritional categories showed a sharp decrease, while Alzheimer's disease and other dementias and Parkinson's disease showed a large increase. …”

Table_4_Prospective Study Reveals Host Microbial Determinants of Clinical Response to Fecal Microbiota Transplant Therapy in Type 2 Diabetes Patients.docx by Dafa Ding (6548732)

“…</p>Results<p>We found that the GM of T2DM patients was reconstituted by FMT. We observed a statistically significant decrease in HbA1c% (from 7.565 ± 0.148 to 7.190 ± 0.210, p<0.01), blood glucose (from 8.483 ± 0.497 to 7.286 ± 0.454 mmol/L, p<0.01), and uric acid (from 309.4 ± 21.5 to 259.1 ± 15.8 µmol/L, p<0.01) while a significant increase in postprandial C-peptide (from 4.503 ± 0.600 to 5.471 ± 0.728 ng/ml, p<0.01) at 12 weeks after FMT. …”

RBM10 promotes transformation-associated processes in small cell lung cancer and is directly regulated by RBM5 by Julie J. Loiselle (4183750)

“…We have recently shown that a decrease in <i>RBM5</i> expression may be a key step in SCLC development, as RBM5 regulated many transformation-associated processes in SCLC cells. …”

Evolutionary Conservation and Diversification of Puf RNA Binding Proteins and Their mRNA Targets by Gregory J. Hogan (160970)

“…<div><p>Reprogramming of a gene’s expression pattern by acquisition and loss of sequences recognized by specific regulatory RNA binding proteins may be a major mechanism in the evolution of biological regulatory programs. …”

Table_1_Simultaneous Separation of Antioxidants and Carbohydrates From Food Wastes Using Aqueous Biphasic Systems Formed by Cholinium-Derived Ionic Liquids.pdf by Catarina M. S. S. Neves (6887705)

“…The development of sustainable and cost-effective technologies to recover these value added compounds will contribute to a significant decrease of the environmental footprint and economic burden of this industry sector. …”

Table_3_Gene Co-expression Network Reveals Potential New Genes Related to Sugarcane Bagasse Degradation in Trichoderma reesei RUT-30.XLSX by Gustavo Pagotto Borin (751443)

“…Our results demonstrate a vast range of new promising targets that merit additional studies to improve the cellulolytic potential of T. reesei strains and to decrease the production costs of 2G ethanol.…”

Table_3_Schwann cell-derived exosomes ameliorate peripheral neuropathy induced by ablation of dicer in Schwann cells.DOCX by Lei Wang (6656)

“…</p>Results<p>Compared to the WT mice, PLP-cKO mice exhibited a significant decrease in motor and sensory conduction velocities, thermal sensitivity, and motor coordination. …”

Early-life iron deficiency persistently disrupts affective behaviour in mice by Anna Gundacker (15351912)

“…</p> <p>Mothers receiving iron-deficient food during pregnancy and lactation exhibited significantly less licking and grooming behaviour, while active pup retrieval and pup ultrasonic vocalizations were unaltered. Adult offspring with a history of foetal and neonatal ID showed an increase in depression- and anxiety-like behaviour, paralleled by a deranged miRNA expression profile in the hippocampus, specifically levels of miR200a and miR200b.…”

Image_1_Genes related to osmoregulation and antioxidation play important roles in the response of Trollius chinensis seedlings to saline-alkali stress.jpg by Rongmiao Hou (14507159)

“…<p>Saline-alkali stress is one of the main abiotic stress factors affecting plant growth and development. Trollius chinensis is a perennial herbal medicinal plant with high values for garden application. …”

Data_Sheet_3_Global, regional, and national burden of chronic respiratory diseases and associated risk factors, 1990–2019: Results from the Global Burden of Disease Study 2019.ZIP... by Xiang Chen (10398)

“…</p>Results<p>In 2019, 454.56 [95% uncertainty interval (UI): 417.35–499.14] million individuals worldwide had a CRD, showing a 39·8% increase compared with 1990. …”

Table_1_Prospective Study Reveals Host Microbial Determinants of Clinical Response to Fecal Microbiota Transplant Therapy in Type 2 Diabetes Patients.xlsx by Dafa Ding (6548732)

“…</p>Results<p>We found that the GM of T2DM patients was reconstituted by FMT. We observed a statistically significant decrease in HbA1c% (from 7.565 ± 0.148 to 7.190 ± 0.210, p<0.01), blood glucose (from 8.483 ± 0.497 to 7.286 ± 0.454 mmol/L, p<0.01), and uric acid (from 309.4 ± 21.5 to 259.1 ± 15.8 µmol/L, p<0.01) while a significant increase in postprandial C-peptide (from 4.503 ± 0.600 to 5.471 ± 0.728 ng/ml, p<0.01) at 12 weeks after FMT. …”

Image_1_The Type I Interferon Pathway Is Upregulated in the Cutaneous Lesions and Blood of Multibacillary Leprosy Patients With Erythema Nodosum Leprosum.TIF by Thabatta Leal Silveira Andrezo Rosa (5489132)

“…During thalidomide administration, the drug of choice for ENL treatment, a decrease in the mRNA and protein levels of some of these genes both in the skin and blood was observed. …”

Effects of acute Theiler’s murine encephalomyelitis virus (TMEV)-infection (<i>experiment I</i>) upon cytokine expression and phenotypical changes in spleens of interleukin-10 rece... by Ann-Kathrin Uhde (3110976)

“…(J) Flow cytometry revealed a relative increase of CD19⁺ B cells and a simultaneous decrease of CD4⁺ T cells (K) in the spleen of infected mice following IL-10R blockade at 14 dpi. …”