Sperm motility is altered in <i>Cfap97d1</i>^{<i>KOMP-/-</i>} mice. حسب Seiya Oura (9234312)

"…<p><b>(A)</b> Curvilinear velocity (VCL) and <b>(B)</b> average path velocity (VAP) values were reduced in <i>Cfap97d1</i>^{<i>KOMP-/-</i>} sperm. …"

Image_3_The atypical chemokine receptor 2 reduces T cell expansion and tertiary lymphoid tissue but does not limit autoimmune organ injury in lupus-prone B6lpr mice.pdf حسب Wenkai Xia (670350)

"…Introduction<p>The atypical chemokine receptor 2 (ACKR2) is a chemokine scavenger receptor, which limits inflammation and organ damage in several experimental disease models including kidney diseases. …"

Image_6_Phenotypic changes of γδ T cells in Plasmodium falciparum placental malaria and pregnancy outcomes in women at delivery in Cameroon.jpeg حسب Chris Marco Mbianda Nana (14492776)

"…This study sought to investigate the involvement of γδ T cells and its subsets in placental Plasmodium falciparum malaria.</p>Methods<p>In a case-control study conducted in Yaoundé, Cameroon from March 2022 to May 2023, peripheral, placental and cord blood samples were collected from 50 women at delivery (29 PM negative: PM- and 21 PM positive: PM+; as diagnosed by light microscopy). …"

Transdifferentiation and <i>CYB561</i> knockdown altered the Fe²⁺ concentrations and expression of iron responsive genes (IRGs) in LNCaP cells. حسب Romie Angelo G. Azur (18547651)

"…<p>LNCaP cells transduced with the scrambled (scr) shRNA control and sh<i>CYB561</i> were grown and maintained in complete media (control) or transdifferentiation media for 14 days followed by Fe²⁺ concentration measurement. <b>(A)</b> CYB561 contributes to cellular iron homeostasis through its ferrireductase function to maintain vesicular redox states. …"

Image_1_Organelle Crosstalk Regulators Are Regulated in Diseases, Tumors, and Regulatory T Cells: Novel Classification of Organelle Crosstalk Regulators.tif حسب Ming Liu (105953)

"…<p>To examine whether the expressions of 260 organelle crosstalk regulators (OCRGs) in 16 functional groups are modulated in 23 diseases and 28 tumors, we performed extensive -omics data mining analyses and made a set of significant findings: (1) the ratios of upregulated vs. downregulated OCRGs are 1:2.8 in acute inflammations, 1:1 in metabolic diseases, 1:1.2 in autoimmune diseases, and 1:3.8 in organ failures; (2) sepsis and trauma-upregulated OCRG groups such as vesicle, mitochondrial (MT) fission, and mitophagy but not others, are termed as the cell crisis-handling OCRGs. …"

Data_Sheet_1_Effects of short-term exercise and endurance training on skeletal muscle mitochondria damage induced by particular matter, atmospherically relevant artificial PM2.5.pd... حسب Wenduo Liu (18066922)

"…</p>Results<p>After 12 weeks of endurance training, the EEC significantly increased (p < 0.000) in the ETR group compared to the SED group. Following a one-week comparison among the four groups with atmospherically relevant artificial PM2.5 exposure and exercise treatment post-endurance training, the EEX group showed improvements in EEC, oxidative metabolism, mitochondrial dynamics, and antioxidant functions. …"

Data_Sheet_1_Tulathromycin metaphylaxis increases nasopharyngeal isolation of multidrug resistant Mannheimia haemolytica in stocker heifers.zip حسب William B. Crosby (13248210)

"…<p>Bovine respiratory disease (BRD) is a leading cause of disease in feedlot and stocker calves with Mannheimia haemolytica (MH) as one of the most common etiologies. …"

Hormone-sensitive BCa cells (MCF-7) comprise 3 subpopulations, distinguished by ER-α46 expression levels. حسب John J. Kim (11191609)

"…<p><b>A</b> False-color micrographs of MCF-7 Cell Types: (1) ER-α66⁺ ∩ ER-α46⁺, (2) ER-α66⁺ ∩ ER-α46^-, and (3) ER-α66^- ∩ ER-α46^-. …"

DataSheet2_α-Mangostin Alleviated Inflammation in Rats With Adjuvant-Induced Arthritis by Disrupting Adipocytes-Mediated Metabolism-Immune Feedback.PDF حسب Ying-Hao Hu (11087037)

"…<p>A previously identified anti-rheumatic compound α-mangostin (MAN) possesses notable metabolism regulatory properties. …"

Data_Sheet_1_Preliminary Results on the Long-Term Effects of Dextromethorphan on MDMA-Mediated Serotonergic Deficiency and Volumetric Changes in Primates Based on 4-[18F]-ADAM PET/... حسب Skye Hsin-Hsien Yeh (12565243)

"…This study aimed to evaluate the long-term neurotoxicity of MDMA after 66 months abstinence and explored whether Dextromethorphan, a non-competitive N-methyl-D-aspartate (NMDA) receptor, could attenuate MDMA-induced neurotoxicity using 4-[¹⁸F]-ADAM, an imaging ligand that selectively targets SERT, with positron emission tomography technology (PET). …"

Image3_Evidence and Potential Mechanism of Action of Lithospermum erythrorhizon and Its Active Components for Psoriasis.tif حسب Jiao Wang (47178)

"…Preclinical evidence has shown that the active components of Lithospermum erythrorhizon exhibit a potential anti-inflammatory effect, promote keratinocyte apoptosis, inhibit keratinocyte proliferation and angiogenesis, and block the cell cycle. …"

Image_15_Organelle Crosstalk Regulators Are Regulated in Diseases, Tumors, and Regulatory T Cells: Novel Classification of Organelle Crosstalk Regulators.tif حسب Ming Liu (105953)

"…<p>To examine whether the expressions of 260 organelle crosstalk regulators (OCRGs) in 16 functional groups are modulated in 23 diseases and 28 tumors, we performed extensive -omics data mining analyses and made a set of significant findings: (1) the ratios of upregulated vs. downregulated OCRGs are 1:2.8 in acute inflammations, 1:1 in metabolic diseases, 1:1.2 in autoimmune diseases, and 1:3.8 in organ failures; (2) sepsis and trauma-upregulated OCRG groups such as vesicle, mitochondrial (MT) fission, and mitophagy but not others, are termed as the cell crisis-handling OCRGs. …"

Changes in apical microvilli and ciliated cells in ChPl in <i>Atp7b</i>^<i>-/-</i> mice. حسب Clorissa L. Washington-Hughes (14375205)

"…<p>(a) H&E staining of sagittal sections from <i>Atp7b-/-</i> and control mouse brains showing 4th ventricle choroid plexus. …"

Table2_Evidence and Potential Mechanism of Action of Lithospermum erythrorhizon and Its Active Components for Psoriasis.docx حسب Jiao Wang (47178)

"…Preclinical evidence has shown that the active components of Lithospermum erythrorhizon exhibit a potential anti-inflammatory effect, promote keratinocyte apoptosis, inhibit keratinocyte proliferation and angiogenesis, and block the cell cycle. …"

Image_6_Organelle Crosstalk Regulators Are Regulated in Diseases, Tumors, and Regulatory T Cells: Novel Classification of Organelle Crosstalk Regulators.tif حسب Ming Liu (105953)

"…<p>To examine whether the expressions of 260 organelle crosstalk regulators (OCRGs) in 16 functional groups are modulated in 23 diseases and 28 tumors, we performed extensive -omics data mining analyses and made a set of significant findings: (1) the ratios of upregulated vs. downregulated OCRGs are 1:2.8 in acute inflammations, 1:1 in metabolic diseases, 1:1.2 in autoimmune diseases, and 1:3.8 in organ failures; (2) sepsis and trauma-upregulated OCRG groups such as vesicle, mitochondrial (MT) fission, and mitophagy but not others, are termed as the cell crisis-handling OCRGs. …"

Image_1_The atypical chemokine receptor 2 reduces T cell expansion and tertiary lymphoid tissue but does not limit autoimmune organ injury in lupus-prone B6lpr mice.pdf حسب Wenkai Xia (670350)

"…Introduction<p>The atypical chemokine receptor 2 (ACKR2) is a chemokine scavenger receptor, which limits inflammation and organ damage in several experimental disease models including kidney diseases. …"

DataSheet_1_ATP-P2X7R pathway activation limits the Tfh cell compartment during pediatric RSV infection.docx حسب Constanza Russo (12559159)

"…To evaluate apoptosis, proliferation, and IL-21 production by cTfh cells, we cultured PBMCs in the presence of Bz-ATP and/or P2X7R antagonist (KN-62) and a flow cytometry analysis was performed.</p>Results<p>In children with severe RSV disease, we observed diminished titers of neutralizing anti-PreF IgG antibodies. …"

Image4_Combination of plasma MMPs and PD-1-binding soluble PD-L1 predicts recurrence in gastric cancer and the efficacy of immune checkpoint inhibitors in non-small cell lung cance... حسب Fumihiko Ando (18512622)

"…The combination of bsPD-L1 and MMPs may represent a non-invasive tool to predict recurrence in GC and the efficacy of ICIs in NSCLC.…"

Image_2_Abnormal Shift in B Memory Cell Profile Is Associated With the Expansion of Circulating T Follicular Helper Cells via ICOS Signaling During Acute HIV-1 Infection.tif حسب Xiaofan Lu (2319541)

"…Twenty-five study subjects were enrolled from the Beijing PRIMO clinical cohort, a prospective cohort of HIV-1-negative men who have sex with men (MSM) for the identification of cases of acute HIV-1 infection (AHI) at Beijing Youan Hospital, Capital Medical University. …"

Data_Sheet_1_Organelle Crosstalk Regulators Are Regulated in Diseases, Tumors, and Regulatory T Cells: Novel Classification of Organelle Crosstalk Regulators.docx حسب Ming Liu (105953)

"…<p>To examine whether the expressions of 260 organelle crosstalk regulators (OCRGs) in 16 functional groups are modulated in 23 diseases and 28 tumors, we performed extensive -omics data mining analyses and made a set of significant findings: (1) the ratios of upregulated vs. downregulated OCRGs are 1:2.8 in acute inflammations, 1:1 in metabolic diseases, 1:1.2 in autoimmune diseases, and 1:3.8 in organ failures; (2) sepsis and trauma-upregulated OCRG groups such as vesicle, mitochondrial (MT) fission, and mitophagy but not others, are termed as the cell crisis-handling OCRGs. …"