Supplementary Material for: Functional Characterization of Patients with Chronic Thromboembolic Disease by Held M. (2840378)

“…<b><i>Methods:</i></b> We compared right heart catheterization and cardiopulmonary exercise test results of patients with CTED [mean pulmonary artery pressure (mPAP) at rest <25 mm Hg, n = 10], chronic thromboembolic pulmonary hypertension (CTEPH, n = 31) and a control group (n = 41) presenting with dyspnea but normal pulmonary vascular imaging and excluded pulmonary hypertension. …”

Decreased dendritic arbor length of principal neurons from the basolateral amygdala (BLA) of short-term sucrose consuming rats compared to control rats. by Masroor Shariff (2583442)

“…<p><b>A</b> shows a scatter-plot of decreased total dendritic arbor (mean ± SEM) from the BLA in short-term sucrose rats (open squares) compared to controls (open circles) (Unpaired two-tailed Students <i>t</i>-test,*<i>P</i> < 0.05, <i>n</i> = 7; control and <i>n</i> = 7; 4 week sucrose). …”

Decreased cellular iron uptake attenuates the effector CD8⁺ T cell response to <i>P</i>. <i>chabaudi</i>. by Sarah K. Wideman (17118275)

Decreased cellular iron uptake disrupts the effector CD4⁺ T cell response to <i>P</i>. <i>chabaudi</i>. by Sarah K. Wideman (17118275)

Multivariable-adjusted odds ratio (aOR) for high biomarkers of iron metabolism according to quartile of lung function. by Jonghoo Lee (4831776)

“…<p>The aOR for hyperferritinemia increased with decreasing quartiles of FEV1% and FVC% (A) in a dose-response manner. …”

Mean WIS in different locations for different transformations applied before scoring. by Nikos I. Bosse (9756108)

“…For large values of <i>a</i>, log(<i>x</i> + <i>a</i>) grows roughly linearly in <i>x</i>, meaning that we expect to observe the same patterns as in the case with no transformation. …”

Time concordance metrics for all TFs, pathways as well as genes using both a minimal |logFC| of 0.5 and 1. by Anika Liu (8411805)

Enzyme kinetics of 245 NA Gly- and 245 NA Gly+ viruses. by Harrison Powell (9040128)

No decrease in positive or negative selection of HY-TCR-transgenic thymocytes in human <i>PTPN22</i> regulon transgenic (BACLYPW) and control mice. by Dennis J. Wu (518789)

AKP-11 and FTY720 prevent the infiltration of mononuclear cells into the CNS of EAE animals and decrease the inflammatory cytokines and protect the MBP and NF-200. by Devadoss J. Samuvel (327215)

Activated CD4+ CD45RO+ memory T-cells decrease secretion of soluble caspase-1 and P2X7R mRNA expression in monocytes leading to a reduced response upon ATP binding. by Vanessa Beynon (153924)

“…A significant decrease of soluble Caspase-1 in the supernatant of cells co-cultured with activated memory T-cells was observed both in the presence and absence of IFNβ; b) intracellular levels of pro-IL-1β measured with an ELISA specific for the immature precursor of IL-1β showed a significant increase in pro-IL-1β levels in the presence of human activated CD4+CD45RO+ memory T-cells (n = 3), cell lysates from adherent monocytes were obtained after removal of non-adherent T-cells after addition of LPS and prior to incubation with ATP c) the ratio of intracellular pro-IL-1β to released soluble Caspase-1 is significantly increased in the presence of human activated CD4+CD45RO+ memory T-cells (n = 3). d) <i>P2X7R</i> mRNA expression in monocytes cultured overnight with activated CD4+CD45RO+ memory T-cells is decreased with and without addition of exogenous IFNβ (n = 3), mRNA was isolated from adherent monocytes after removal of non-adherent T-cells after addition of LPS and prior to incubation with ATP (Data are shown as means ± SD of duplicate cultures; *p<0.05; **p<0.01 employing repeated measures ANOVA with post-hoc Bonferroni adjustment for multiple comparisons to avoid random correlations); e) Ca²⁺-influx measurement in monocytes cultured with activated human CD4+CD45RO+ memory T-cells in the presence of IFNβ demonstrates the absence of slow sustained Ca²⁺-influx mediated by ATP binding to the purinergic P2X7-receptor (representative of 3 independent experiments); f) Annexin V staining of monocytes coincubated with T-cells and stimulated with LPS was measured by flow cytometry (representative flow cytometry histogram of n = 5).…”

Different cases of erroneously annotated fractures in pediatric wrist radiographs. by Eszter Nagy (398278)

Nampt inhibition leads to decrease in Rev-erb alpha expression and glucagon secretion in alphaTC1-9 cells and pancreatic alpha cells. by Elaine Vieira (174928)

“…Conversely, high glucose will inhibit AMPK-Nampt-Sirt pathway and consequently Rev-erb alpha expression levels leading to a decrease in glucagon release.</p>…”

Expression level of β₁AR was decreased and β₂AR was preserved in the pulmonary arteries of IH-rats. by Hisashi Nagai (650547)

<i>Zfp804A</i> mRNA expression in the developing rat brain. by Katja Hvid Hinna (766041)

“…The zfp804A primer set was used and data are presented as means ± SEM. …”

The total healthcare costs for IS. by Hee Jung Son (14285076)

“…This study investigated the incidence and treatment trends of IS in South Korea using data obtained from the Health Insurance Review and Assessment Service. A total of 169,244 patients (mean age: 58.0 years) diagnosed from 2010 to 2019 were included in the study. …”

SHIP-1 decreases NOD1-induced NF-κB activation in monocytes/macrophages and interacts with XIAP in the course of NOD1 signaling. by Claude Condé (150801)

The number of PS and TS cases from 2010 to 2019. by Hee Jung Son (14285076)

“…This study investigated the incidence and treatment trends of IS in South Korea using data obtained from the Health Insurance Review and Assessment Service. A total of 169,244 patients (mean age: 58.0 years) diagnosed from 2010 to 2019 were included in the study. …”

Hepatic B1 cells increase whereas PC B1 cells decrease after <i>S</i>. <i>japonicum</i> infection. by Liang Yong (6836771)

The VPAC1 protein level is decreased in U937 cells after 48 h from miR-525-5p transfection. by Elisa Cocco (362650)