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21281
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21284
Image_2_Growth Inhibitory Effects of Dipotassium Glycyrrhizinate in Glioblastoma Cell Lines by Targeting MicroRNAs Through the NF-κB Signaling Pathway.TIF
Published 2019“…<p>It has been shown that nuclear factor kappa-B (NF-κB) is constitutively activated in glioblastoma (GBM), suggesting that the pathway could be a therapeutic target. Glycyrrhetic acid (GA), a compound isolated from licorice (Glycyrrhiza glabra), has been shown to decrease cell viability and increases apoptosis in human cancer cell lines by NF-κB signaling pathway suppression. …”
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21285
Image_1_Growth Inhibitory Effects of Dipotassium Glycyrrhizinate in Glioblastoma Cell Lines by Targeting MicroRNAs Through the NF-κB Signaling Pathway.TIF
Published 2019“…<p>It has been shown that nuclear factor kappa-B (NF-κB) is constitutively activated in glioblastoma (GBM), suggesting that the pathway could be a therapeutic target. Glycyrrhetic acid (GA), a compound isolated from licorice (Glycyrrhiza glabra), has been shown to decrease cell viability and increases apoptosis in human cancer cell lines by NF-κB signaling pathway suppression. …”
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21286
Data_Sheet_1_Epinephrine May Contribute to the Persistence of Traumatic Memories in a Post-traumatic Stress Disorder Animal Model.pdf
Published 2020“…After induction of PTSD, Pnmt-KO mice showed a decrease in freezing, as well as an increase in open arm entries and transitions between compartments compared to WT. …”
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21287
Image_3_Growth Inhibitory Effects of Dipotassium Glycyrrhizinate in Glioblastoma Cell Lines by Targeting MicroRNAs Through the NF-κB Signaling Pathway.TIF
Published 2019“…<p>It has been shown that nuclear factor kappa-B (NF-κB) is constitutively activated in glioblastoma (GBM), suggesting that the pathway could be a therapeutic target. Glycyrrhetic acid (GA), a compound isolated from licorice (Glycyrrhiza glabra), has been shown to decrease cell viability and increases apoptosis in human cancer cell lines by NF-κB signaling pathway suppression. …”
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21288
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21289
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21290
Synthesis of Triazole-Substituted Quinazoline Hybrids for Anticancer Activity and a Lead Compound as the EGFR Blocker and ROS Inducer Agent
Published 2018“…A series of triazole-substituted quinazoline hybrid compounds were designed and synthesized for anticancer activity targeting epidermal growth factor receptor (EGFR) tyrosine kinase. …”
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21291
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21292
Precursor B Cells Increase in the Lung during Airway Allergic Inflammation: A Role for B Cell-Activating Factor
Published 2016“…</p><p>Conclusion</p><p>Our data support the concept of a BAFF-mediated role for B cell precursors in allergic airway inflammation.…”
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21293
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21294
(modified from EDENetwork, [<b>75</b>]): Simplified network of <i>Trypanosoma cruzi</i> including stocks of near-clades I, II and III (respectively yellow, blue and green nodes) and scanned for decreasing thresholds from the (a) fully connected network (all pairwise links included) to the (b) percolation threshold (Dp, all links corresponding to distances superior to Dp excluded) and to (c) a lower threshold chosen to illustrate the sequential split of clusters at decreasing thresholds, and main properties of nodes and networks used herein.
Published 2014“…<p>(modified from EDENetwork, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0103213#pone.0103213-Kivela1" target="_blank">[<b>75</b>]</a>): Simplified network of <i>Trypanosoma cruzi</i> including stocks of near-clades I, II and III (respectively yellow, blue and green nodes) and scanned for decreasing thresholds from the (a) fully connected network (all pairwise links included) to the (b) percolation threshold (Dp, all links corresponding to distances superior to Dp excluded) and to (c) a lower threshold chosen to illustrate the sequential split of clusters at decreasing thresholds, and main properties of nodes and networks used herein.…”
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21295
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21296
Image_1_Reduced Annexin A1 Secretion by ABCA1 Causes Retinal Inflammation and Ganglion Cell Apoptosis in a Murine Glaucoma Model.TIF
Published 2018“…Previous studies have shown an association between ABCA1 deficiency and retinal inflammation. Using a mouse model of ischemia-reperfusion (IR) induced by acute intraocular pressure elevation, we found that the retinal expression of ABCA1 protein was decreased. …”
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21297
Particulate metal exposures induce plasma metabolome changes in a commuter panel study
Published 2018“…Two-hour changes in proinflammatory biomarkers hs-CRP, IL-6, IL-8, and IL-1β were also associated with 10-hr changes in the plasma metabolome, suggesting diverse amino acid, leukotriene, and antioxidant metabolism effects. A putatively identified metabolite, 20-OH-LTB4, decreased after in-vehicle exposure to particulate metals, suggesting a subclinical immune response.…”
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21298
Effect of Treatment with Interferon Beta-1a on Changes in Voxel-Wise Magnetization Transfer Ratio in Normal Appearing Brain Tissue and Lesions of Patients with Relapsing–Remitting...
Published 2014“…</p><p>Methods</p><p>Increasing (suggestive of remyelination) and decreasing (suggestive of demyelination) VW-MTR changes in NABT and in T2, T1 and gadolinium (Gd)-enhancing lesion volume were measured over 24 weeks in 23 patients treated with IFN β-1a SC and in 15 HCs (where applicable). …”
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21299
Presentation_1_The Non-amyloidal Component Region of α-Synuclein Is Important for α-Synuclein Transport Within Axons.pdf
Published 2020“…Excess α-syn or fPD mutant α-syn<sup>A53T</sup> accumulates within larval axons perturbing the transport of synaptic proteins. …”
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21300
Presentation_1_The Non-amyloidal Component Region of α-Synuclein Is Important for α-Synuclein Transport Within Axons.pdf
Published 2020“…Excess α-syn or fPD mutant α-syn<sup>A53T</sup> accumulates within larval axons perturbing the transport of synaptic proteins. …”