SRC-2 Coactivator Deficiency Decreases Functional Reserve in Response to Pressure Overload of Mouse Heart by Erin L. Reineke (107382)

“…Interestingly, the transcriptional regulator steroid receptor coactivator-2, SRC-2 is often decreased during cardiac failure in humans. We postulated that SRC-2 suppression plays a mechanistic role in the stress response and that SRC-2 activity is an important regulator of the adult heart gene expression profile. …”

Decreased FoxO3 nuclear localization during late erythroblast maturation in β-thalassemia. by Naruchit Thanuthanakhun (4570966)

Melatonin attenuates nicotine-induced autophagy and neurological changes by decreasing the production of reactive oxygen species by Yue Feng (158140)

“…Subsequent western blotting results showed that nicotine induced increase in the levels of LC3B-II and Beclin1, and decreased SQSTM1/p62 in a concentration-dependent manner. …”

Data_Sheet_1_Decreased Exosomal Acetylcholinesterase Activity in the Plasma of Patients With Parkinson’s Disease.DOCX by Kyu Hwan Shim (9117111)

“…Remarkably, exosomal AChE activity was significantly decreased in PD compared to HC (P = 0.002). Moreover, exosomal AChE activity in PD revealed a strong negative correlation with disease severity, including H&Y (P = 0.007) and UPDRS part III (P = 0.047) scores. …”

Nitric Oxide Releasing Hydrogel Nanoparticles Decreases Epithelial Cell Injuries Associated With Airway Reopening. by Shurbaji, Samar

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Rh1 levels are decreased in <i>Vps26</i> mutant PRs after internalization. by Shiuan Wang (207351)

“…<p>(A) Western blots for Rh1 and TRP on control (iso) and <i>Vps26¹</i> mutant PRs. …”

Knockdown of PABPC1 with siRNA decreases PSA luciferase activity and PSA protein levels. by Kurtis Eisermann (95302)

BMP signaling, as measured by its downstream signal, phospho Mad is decreased in motor protein mutants. by Min Jung Kang (616217)

“…<b>D:</b> In contrast, quantitative analysis of p-Mad intensity in roblk−/− larval brains show a significant decrease compared to wild type (p = 0.0404), while a decreasing trend is seen in larval brains expressing polyQ77, but this is not significant (p = 0.08). …”

siATF2 treatment decreases γ-globin gene expression in K562 cells. by Li Liu (75607)

Increased and Decreased Nodal/Activin Signaling Leads to Transcriptional Regulation of Specific Subsets of Target Genes. by Kian Leong Lee (25035)

NVP-AUY922 decreases clonogenic survival due to ionising radiation <i>in vitro</i>. by Shane Zaidi (170919)

Plasma levels of tumor suppressor miRNAs are decreased in individuals with detectable KSHV oral shedding. by Minako Ikoma (4843458)

QN treatment decreases Hz content on <i>S. mansoni</i> females <i>in vivo</i>. by Juliana B. R. Corrêa Soares (262743)

Decreased chondrocytes proliferation, shortening of pre-hypertrophic and hypertrophic zone in BMP signaling deficient mice. by Bettina Keller (231677)

“…(G–I) BrdU staining revealed a decreased proliferation rate in <i>Smad1^cKO/cKO;Smad5^+/−</i> compared to WT control (P<0.02).…”

Western blot revealed decreased expression of CSE and CBS in obstructed ileal smooth muscle tissues. by Xin Guo (123593)

AIM-100 reduces dsRNA silencing in body wall muscle and decreases DA neurodegeneration. by Anthony L. Gaeta (13272609)

Overexpression of MKP-1 decreases the IL-1β-mediated activation of the CCL2 gene. by Susan J. Burke (130329)

The proportion of alveolar type 1 cells decreases in murine hypoplastic congenital diaphragmatic hernia lungs by Tram Mai Nguyen (6597863)

“…Based on this model, the alveolar epithelium showed a decrease in the number of alveolar type 1 cell in congenital diaphragmatic hernia lungs while type 2 cell population remains unchanged.…”

<i>in vivo</i> MARCKS knockdown decreased VSMC proliferation after transmural aortic injury. by Dan Yu (214174)

“…</b> Topical treatment with MARCKS siRNA at the time of injury prevented vessel wall thickening. <b>C.</b> The decreased wall thickness was due to a decrease in VSMC proliferation as determined by staining with DAPI. …”

Impaired Ubr5 function results in increased canonical and decreased non-canonical HH signalling. by David Mellis (2833469)