Video_6_Murine Metatarsus Bone and Joint Collagen-I Fiber Morphologies and Networks Studied With SHG Multiphoton Imaging.AVI by Martin Vielreicher (10957656)

“…Multiphoton Second Harmonic Generation (SHG) microscopy, is able to visualize the sterical topology of the collagen-I fibrillar network in 3D, in a minimally invasive and label-free manner. Penetration depths exceed those of conventional visible light imaging and can be further optimized through employing decalcification or optical clearing processing ex vivo. …”

Data Sheet 3_Global, regional and national mortality burden of laryngeal cancer attributable to occupational exposure to sulfuric acid and asbestos: 1990–2021 and projections to 20... by Xin Gong (592328)

“…Occupational exposure to sulfuric acid (OESA) and asbestos (OEA) is a recognized risk factor for LC, but the associated mortality burden remains unclear. …”

Image_1_Effects of Prone Positioning on Respiratory Mechanics and Oxygenation in Critically Ill Patients With COVID-19 Requiring Venovenous Extracorporeal Membrane Oxygenation.TIF by Driss Laghlam (11055954)

“…</p>Methods:<p>We prospectively analyzed the effects of PP on respiratory mechanics from continuous data with over a thousand time points during 16-h PP sessions in patients with COVID-19 and ARDS under VV-ECMO conditions. …”

Image_3_Metagenome Analysis of Intestinal Bacteria in Healthy People, Patients With Inflammatory Bowel Disease and Colorectal Cancer.tif by Yongshun Ma (9737837)

“…Objectives<p>Several reports suggesting that the intestinal microbiome plays a key role in the development of inflammatory bowel disease (IBD) or colorectal cancer (CRC), but the changes of intestinal bacteria in healthy people, patients with IBD and CRC are not fully explained. …”

Spirometry results. by Imane Salmam (21485704)

“…</p><p>Methods and findings</p><p>A structured search was conducted across the MEDLINE, Embase, CINAHL, and Web of Science databases to identify cross-sectional and longitudinal cohort studies on physical and cardiorespiratory deficits in adults with long COVID. …”

Table_2_Hepatoma-Derived Growth Factor and DDX5 Promote Carcinogenesis and Progression of Endometrial Cancer by Activating β-Catenin.docx by Chunhua Liu (502032)

“…Immunohistochemistry analysis showed that high expression of DDX5 constituted an unfavorable factor with respect to the clinicopathological characteristics of EC tissues and that HDGF and DDX5 high expression (HDGF+/DDX5+) led to a worse prognosis for patients with EC (P < 0.001). …”

DataSheet1_Investigation of the Anti-Inflammatory Activity of Fusaproliferin Analogues Guided by Transcriptome Analysis.PDF by Qi-Xuan Kuang (11773529)

“…Surface plasmon resonance assays (SPR) combined with molecular docking analyses were finally applied to evaluate the affinity interactions between 1-4 and TLR4 and provide a possible interpretation of the downregulation of related signaling pathways.…”

Image_1_Protective Effects of Phyllanthus amarus Against Lipopolysaccharide-Induced Neuroinflammation and Cognitive Impairment in Rats.tif by Akilandeshwari Alagan (6794390)

“…All groups were challenged with LPS (1 mg/kg) given intraperitoneally a day prior to the behavioral tests except for the negative control group. …”

Image_7_Implication of Melanopsin and Trigeminal Neural Pathways in Blue Light Photosensitivity in vivo.TIF by Veronika Marek (6725135)

“…The only drug that significantly decreased the blue-light aversion was the intraperitoneally injected melanopsin antagonist. …”

Data_Sheet_1_Comparative Decomposition of Humans and Pigs: Soil Biogeochemistry, Microbial Activity and Metabolomic Profiles.docx by Jennifer M. DeBruyn (753946)

Table_1_New Achievements in High-Pressure Processing to Preserve Human Milk Bioactivity.docx by Aleksandra Wesolowska (5981699)

“…<p>High-pressure processing (HPP) is a non-thermal technology that is being increasingly applied in food industries worldwide. …”

Image_1_Differential microbiome features in lake–river systems of Taihu basin in response to water flow disturbance.pdf by Peng Xiao (172430)

“…Moreover, path analysis indicated that microeukaryotic communities exhibited a stronger response to water flow disturbances than bacterial communities. …”

Image_4_Single cell analysis of short-term dry eye induced changes in cornea immune cell populations.jpg by Jehan Alam (5577734)

“…Significant changes in expression of 1,365 genes (adj p < 0.0001) were noted in rMP with increases in cytokines and chemokines (Tnf, Cxcl1, Ccl12, Il1rn), inflammatory markers (Vcam, Adam17, Junb), the TAM receptor (Mertk), and decreases in complement and MHCII genes. A differentiation trajectory from monocytes to terminal state rMP was found. …”

Image_2_Single cell analysis of short-term dry eye induced changes in cornea immune cell populations.jpg by Jehan Alam (5577734)

“…Significant changes in expression of 1,365 genes (adj p < 0.0001) were noted in rMP with increases in cytokines and chemokines (Tnf, Cxcl1, Ccl12, Il1rn), inflammatory markers (Vcam, Adam17, Junb), the TAM receptor (Mertk), and decreases in complement and MHCII genes. A differentiation trajectory from monocytes to terminal state rMP was found. …”

Image2_Interleukin 9 mediates T follicular helper cell activation to promote antibody responses.jpeg by Taiki Sato (394623)

“…Accumulating evidence indicates a crucial role for interleukin-9 (IL-9) in the formation of germinal centers (GCs), enhancing the generation of class-switched high-affinity antibodies. …”

Table_1_Myricetin Attenuated Diabetes-Associated Kidney Injuries and Dysfunction via Regulating Nuclear Factor (Erythroid Derived 2)-Like 2 and Nuclear Factor-κB Signaling.docx by Zi-Jun Yang (6822599)

“…Moreover, inhibition of IκB/NF-κB (P65) signaling pathway is independent of the regulation of Nrf2. Thus, Myr could be a potential treatment for preventing the development and progression of DM-associated kidney injuries and dysfunction.…”

Image_1_Twenty-Four Hour Blood Pressure Response to Empagliflozin and Its Determinants in Normotensive Non-diabetic Subjects.JPEG by Anne Zanchi (645982)

“…</p>Methods<p>In this post-hoc analysis of a double-blind, randomized, placebo-controlled study examining the renal effects of empagliflozin 10 mg vs. placebo in untreated normotensive non-diabetic subjects, the 1-month changes in 24 h ambulatory BP were analyzed in 39 subjects (13 placebo/26 empagliflozin) in regard to changes in biochemical and hormonal parameters.…”

Inter-rater agreement of AGREE II domains. by Gustavo Angel (14676166)

Image_2_The aberrant dynamic amplitude of low-frequency fluctuations in melancholic major depressive disorder with insomnia.TIF by Zijing Deng (13276731)

“…Importantly, the right MTG/STG may play a critical role in patients with melancholic MDD with more severe insomnia.…”

Cyclic Tetrathiophenes Planarized by Silicon and Sulfur Bridges Bearing Antiaromatic Cyclooctatetraene Core: Syntheses, Structures, and Properties by Takeshi Ohmae (1934089)

“…In comparison of the ¹H NMR chemical shifts of <b>1</b>−<b>3</b> with those of the corresponding precursors, upfield shifts due to a paratropic ring current in the COT ring were observed and the degree of shift increased with increasing planarity of the COT ring. …”