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225961
RB1CC1 binds to and activates the promoters of <i>RB1</i>, <i>p16</i> and <i>p21</i>, cooperating with p53 and/or hSNF5.
Published 2010“…<p>(<b>A</b>) Chromatin immunoprecipitation (ChIP) assay was performed in HeLa cells. …”
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225962
Table2_Isoquercitrin alleviates pirarubicin-induced cardiotoxicity in vivo and in vitro by inhibiting apoptosis through Phlpp1/AKT/Bcl-2 signaling pathway.XLSX
Published 2024“…Isoquercitrin (IQC) is a natural flavonoid with anti-oxidant and anti-apoptosis properties. …”
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225963
Data_Sheet_1_Sexual Dimorphisms of Protein-Coding Gene Profiles in Placentas From Women With Systemic Lupus Erythematosus.PDF
Published 2022“…The results suggest that the SLE-dysregulated protein-coding genes in placentas may contribute to the pathophysiological progress of SLE pregnancies in a fetal sex-specific manner, leading to adverse pregnancy outcomes.…”
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225964
Video_7_Additional Improvement of Respiratory Technique on Vascular Function in Hypertensive Postmenopausal Women Following Yoga or Stretching Video Classes: The YOGINI Study.MOV
Published 2020“…</p><p>Study Design: Hypertensive postmenopausal women were recruited and randomized for 12 weeks, twice a week, of supervised yoga or stretching video classes of 75 min for 12 weeks associated or not with respiratory technique. …”
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225965
Different subregional metabolism patterns in patients with cerebellar ataxia by <sup>18</sup>F-fluorodeoxyglucose positron emission tomography
Published 2017“…<div><p>We evaluated cerebellar subregional metabolic alterations in patients with cerebellar ataxia, a representative disease involving the spinocerebellum. …”
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225966
Minimum data set used in the article.
Published 2025“…It analyzed variation patterns of soil carbon, nitrogen, and phosphorus across different land-use types in the study area and explored the impacts of land-use types and seasonal climate fluctuations on these soil elements, aiming to provide a scientific basis for soil management. Results showed that during 2018–2019, the average organic carbon content in forestland soil (48.82 g/kg) was higher than that in grassland (38.32 g/kg) and cropland (30.80 g/kg). …”
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225967
Imaging c-Met expression using 18F-labeled binding peptide in human cancer xenografts
Published 2018“…<div><p>Objectives</p><p>c-Met is a receptor tyrosine kinase shown inappropriate expression and actively involved in progression and metastasis in most types of human cancer. …”
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225968
Table_2_Impact of BAFF Blockade on Inflammation, Germinal Center Reaction and Effector B-Cells During Acute SIV Infection.DOCX
Published 2020“…From day 2 post-infection (dpi), Treated macaques received one weekly injection of BR3-Fc molecule, a soluble BAFF antagonist, for 4 weeks. Whereas, the kinetics of CD4<sup>+</sup> T-cell loss and plasma viral loads were comparable in both groups, BAFF blockade delayed the peak of inflammatory cytokines (CXCL10, IFNα), impaired the renewal of plasmacytoid dendritic cells and fostered the decline of plasma CXCL13 titers after 14 dpi. …”
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225969
Data_Sheet_2_Perceived Stress and Coping Strategies Among Undergraduate Health Science Students of Jimma University Amid the COVID-19 Outbreak: Online Cross-Sectional Survey.xls
Published 2021“…</p><p>Conclusion: Over one-third of the participants had a high level of perceived stress, and the majority of them were practicing effective means of coping with stress. …”
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225970
<sup>18</sup>F-FET MicroPET and MicroMRI for Anti-VEGF and Anti-PlGF Response Assessment in an Orthotopic Murine Model of Human Glioblastoma
Published 2015“…Further, PlGF and VEGFR-1 expression were examined in a subset of the xenograft tumours and in 13 GBM patient tumours.…”
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225971
Presentation_5_Impact of BAFF Blockade on Inflammation, Germinal Center Reaction and Effector B-Cells During Acute SIV Infection.pptx
Published 2020“…From day 2 post-infection (dpi), Treated macaques received one weekly injection of BR3-Fc molecule, a soluble BAFF antagonist, for 4 weeks. Whereas, the kinetics of CD4<sup>+</sup> T-cell loss and plasma viral loads were comparable in both groups, BAFF blockade delayed the peak of inflammatory cytokines (CXCL10, IFNα), impaired the renewal of plasmacytoid dendritic cells and fostered the decline of plasma CXCL13 titers after 14 dpi. …”
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225972
Image_1_Long Noncoding RNA X-Inactive-Specific Transcript Promotes the Secretion of Inflammatory Cytokines in LPS Stimulated Astrocyte Cell Via Sponging miR-29c-3p and Regulating N...
Published 2021“…</p>Results<p>XIST expression and NFAT5 protein level was increased, whereas miR-29c-3p expression was decreased in the epilepsy rat model and LPS-treated CTX-TNA2 cells. …”
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225973
DataSheet_1_Jianpi Huayu Decoction Attenuates the Immunosuppressive Status of H22 Hepatocellular Carcinoma-Bearing Mice: By Targeting Myeloid-Derived Suppressor Cells.pdf
Published 2020“…Therefore, that the proportion of CD11b<sup>+</sup>Gr-1<sup>+</sup> cells increased in the spleen of tumor-bearing hosts may not be villainy after treatment, when these drugs suppress the immunosuppressive ability of CD11b<sup>+</sup>Gr-1<sup>+</sup> cells and promote it mature to replenish dendritic cell, at the same time. Generally, JHD may be a complementary and alternative drug for attenuating the immunosuppressive status induced by hepatocellular carcinoma, possibly by promoting differentiation and inhibiting the immunosuppressive activity of MDSCs.…”
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225974
Characteristics of the 12 included RCTs.
Published 2024“…</p><p>Results</p><p>Our meta-analysis included a total of 12 studies. Overall analysis indicated that ICIs plus chemotherapy could significantly improve OS (HR = 0.79; 95% CI: 0.74–0.84; <i>I</i><sup>2</sup> = 44.4%, <i>P</i> = 0.055), PFS (HR = 0.62; 95% CI: 0.59–0.67; <i>I</i><sup>2</sup> = 75.3%, <i>P</i> = 0.000), and ORR (RR = 1.48; 95% CI: 1.27–1.73; <i>I</i><sup>2</sup> = 79.0%, <i>P</i> = 0.000) when compared to chemotherapy treatments. …”
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225975
Image1_Naringenin Attenuates Non-Alcoholic Fatty Liver Disease by Enhancing Energy Expenditure and Regulating Autophagy via AMPK.tif
Published 2021“…L02 and Huh-7 cells were induced by sodium oleate to establish a NAFLD cell model. The effects of NAR on lipid accumulation were detected by oil red O staining. …”
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225976
Image_2_The effect of live-performed music therapy with physical contact in preterm infants on parental perceived stress and salivary cortisol levels.JPEG
Published 2024“…Introduction<p>Parents of preterm infants face a stressful life event which might have long term impact on the parent–child relation as well as on the infant’s cognitive and socio-emotional development. …”
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225977
Presentation_1_Transcriptome analysis reveals differences in cell cycle, growth and migration related genes that distinguish fibroblasts derived from pre-invasive and invasive brea...
Published 2023“…Despite standardized treatment involving lumpectomy and radiation therapy, up to 25% of patients with DCIS experience disease recurrence often with invasive ductal carcinoma (IDC), indicating that a subset of patients may be under-treated. As most DCIS cases will not progress to invasion, many patients may experience over-treatment. …”
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225978
Data Sheet 2_Cardioprotective effect of Yiqi Huoxue decoction on post-myocardial infarction injury mediated by Ca2+ flux through MAMs.pdf
Published 2025“…Yiqi Huoxue decoction (YQHX), a Traditional Chinese Medicine formula, shows potential for myocardial infarction (MI) prevention and treatment. …”
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225979
Inhibition of experimental autoimmune encephalomyelitis by tolerance-promoting DNA vaccination focused to dendritic cells
Published 2018“…<div><p>In this study we analysed the effects of prophylactic biolistic DNA vaccination with plasmids encoding the encephalitogenic protein myelin oligodendrocyte glycoprotein (MOG) on the severity of a subsequently MOGp35-55-induced EAE and on the underlying immune response. …”
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225980
Table 5_Clinical effect of unilateral biportal minimally invasive surgery in the treatment of patients with spinal degenerative diseases based on intelligent multimodal reconstruct...
Published 2025“…Objective<p>To explore the effect of unilateral biportal minimally invasive surgery in the treatment of patients with spinal degenerative diseases based on intelligent multimodal reconstruction technology.</p>Methods<p>A total of 100 patients with spinal degenerative diseases treated with unilateral biportal endoscopy during 2023–2024 in Orthopedics Center of our hospital were selected as research objects. …”