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27122
Presentation_1_Deciphering the Mechanism of Inhibition of SERCA1a by Sarcolipin Using Molecular Simulations.pdf
Published 2021“…Sarcolipin (SLN), a transmembrane peptide, regulates the activity of SERCA1a by decreasing its Ca<sup>2+</sup> transport rate, but its mechanism of action is still not well-understood. …”
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27123
datasheet1_Bellidifolin Ameliorates Isoprenaline-Induced Myocardial Fibrosis by Regulating TGF-β1/Smads and p38 Signaling and Preventing NR4A1 Cytoplasmic Localization.pdf
Published 2021“…In CFs, inhibition of p38 by SB203580 inhibited the phosphorylation of NR4A1 and did not limit Smad3 phosphorylation, and blocking TGF-β signaling by LY2157299 and SB203580 could decrease the expression of α-SMA, collagen I and III. …”
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27124
DataSheet_1_PDE2 Inhibits PKA-Mediated Phosphorylation of TFAM to Promote Mitochondrial Ca2+-Induced Colorectal Cancer Growth.docx
Published 2021“…Activation of mitochondrial PDE2 significantly inhibited the activity of mitochondrial protein kinase A (PKA), which subsequently leads to decreased phosphorylation of TFAM. …”
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27125
The pro#3 domain of NFIA is indispensable for driving adipogenesis.
Published 2020“…<p>(A) Control cells, Cre-expressing cells and cells expressing cre as well as either full-length NFIA or Δpro#3 mutant were stained with Oil-Red-O seven days after inducing adipocyte differentiation. …”
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27126
Insulin inhibited miR-99a expression, but induced glucose consumption and lactate production, and increased the expression of mTOR, HIF-1α and PKM2 in HepG2 and HL7702 cells.
Published 2013“…Relative miR-99a expression levels were normalized to U6. Data were presented by mean±SE (n = 3). **, indicates significant decrease compared to the cells without insulin treatment (p<0.01). …”
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27127
Hsc70 prevented Rab1A degradation.
Published 2014“…(B) Hsc70 knockdown decreased the level of Rab1A protein under stress conditions. …”
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27128
Presentation_1_Deciphering the Mechanism of Inhibition of SERCA1a by Sarcolipin Using Molecular Simulations.pdf
Published 2022“…Sarcolipin (SLN), a transmembrane peptide, regulates the activity of SERCA1a by decreasing its Ca<sup>2+</sup> transport rate, but its mechanism of action is still not well-understood. …”
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27129
DataSheet1_Effect of blueberry intervention on endothelial function: a systematic review and meta-analysis.ZIP
Published 2024“…Subgroup analysis indicated a significant decrease in blood pressure (Systolic blood pressure [SBP]: −3.92 mmHg; 95% CI: −6.88, −0.97; I<sup>2</sup> = 20% and DBP: −2.20 mmHg; 95% CI: −4.13, −0.27; I<sup>2</sup> = 11%) in the smoking population. …”
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27130
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27131
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27132
DataSheet_1_Lactate Dehydrogenase-A (LDH-A) Preserves Cancer Stemness and Recruitment of Tumor-Associated Macrophages to Promote Breast Cancer Progression.pdf
Published 2021“…Secondly, the properties of cancer stemness were significantly suppressed in MDA-MB-231-shLDHA or A549-shLDHA cancer cells, including the decrease of ALDH<sup>+</sup> cells proportion, the repression of sphere formation and cellular migration, and the reduction of stemness genes (SOX2, OCT4, and NANOG) expression. …”
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27133
Image_1_A Functional Human-on-a-Chip Autoimmune Disease Model of Myasthenia Gravis for Development of Therapeutics.tif
Published 2021“…This decrease in NMJ stability was dose-dependent over a concentration range of 0.01–20 μg/mL. …”
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27134
E16 UGS cultured in the presence or absence of testosterone and DFMO.
Published 2015“…In the no steroid control media, the urogenital epithelium remained smooth with no evidence of prostatic bud formation (A). After six days of treatment with testosterone, the UGS underwent prolific bud formation (B). …”
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27135
Exercise testing criteria to diagnose lower extremity peripheral artery disease assessed by computed-tomography angiography
Published 2019“…Aims were to define the sensitivity and specificity of several exercise tests to detect peripheral artery disease (PAD), and to assess whether or not defined criteria defined in patients suspected of having a PAD show a difference dependent on the resting ABI.…”
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27140