Showing 29,181 - 29,200 results of 224,509 for search '(( a ((((larger decrease) OR (a decrease))) OR (linear decrease)) ) OR ( a large decrease ))', query time: 1.36s Refine Results
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    Structural Insights into the Role of the Stereochemistry of the Cyclopropyl Ring in the Inhibitory Activity of Xeruborbactam against SME‑1 Class A Carbapenemase by Kunal Dhankhar (14586938)

    Published 2025
    “…Although both inhibitors bind covalently to Ser70 in SME-1, the 2<i>R</i>,3<i>S</i>-isomer adopts a different conformation of the cyclopropyl ring, which makes the C3 carbon much farther from His105, Asn132, and Lys73, thereby decreasing the binding affinity and <i>K</i><sub>i</sub>(app) of the isomer. …”
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  18. 29198

    Structural Insights into the Role of the Stereochemistry of the Cyclopropyl Ring in the Inhibitory Activity of Xeruborbactam against SME‑1 Class A Carbapenemase by Kunal Dhankhar (14586938)

    Published 2025
    “…Although both inhibitors bind covalently to Ser70 in SME-1, the 2<i>R</i>,3<i>S</i>-isomer adopts a different conformation of the cyclopropyl ring, which makes the C3 carbon much farther from His105, Asn132, and Lys73, thereby decreasing the binding affinity and <i>K</i><sub>i</sub>(app) of the isomer. …”
  19. 29199
  20. 29200

    A Customized Pigmentation SNP Array Identifies a Novel SNP Associated with Melanoma Predisposition in the <em>SLC45A2</em> Gene by Maider Ibarrola-Villava (223306)

    Published 2011
    “…Furthermore, individuals carrying two or more mutations in <em>MC1R</em>, a well-known low penetrance melanoma-predisposing gene, had a decreased MM risk if concurrently bearing the <em>SLC45A2</em> protective variant. …”