Hsc70 Contributes to Cancer Cell Survival by Preventing Rab1A Degradation under Stress Conditions by Masako Tanaka (560084)

“…Hsc70 interacted with Rab1A in a chaperone-dependent manner. In addition, Hsc70 knockdown decreased the level of Rab1A and increased the level of its ubiquitination under stress conditions, suggesting that Hsc70 prevented the degradation of Rab1A denatured by stress exposure. …”

Image_7_GM-CSF-activated STAT5A regulates macrophage functions and inflammation in atherosclerosis.png by Jan Nagenborg (14771194)

“…These changes could partially be confirmed at functional level, with significant increases in apoptosis and decreases in lipid uptake and IL-6, IL-8, and TNFa cytokine secretion after STAT5A knockdown. …”

Image_6_GM-CSF-activated STAT5A regulates macrophage functions and inflammation in atherosclerosis.png by Jan Nagenborg (14771194)

“…These changes could partially be confirmed at functional level, with significant increases in apoptosis and decreases in lipid uptake and IL-6, IL-8, and TNFa cytokine secretion after STAT5A knockdown. …”

Image_2_GM-CSF-activated STAT5A regulates macrophage functions and inflammation in atherosclerosis.png by Jan Nagenborg (14771194)

“…These changes could partially be confirmed at functional level, with significant increases in apoptosis and decreases in lipid uptake and IL-6, IL-8, and TNFa cytokine secretion after STAT5A knockdown. …”

Data_Sheet_1_The G2A Receptor Controls Polarization of Macrophage by Determining Their Localization Within the Inflamed Tissue.PDF by Katharina Kern (5804552)

“…Fittingly neutrophil efferocytosis was decreased in G2A-deficient mice and several lipids, which are released by neutrophils and promote G2A-mediated chemotaxis, were increased in the inflamed tissue. …”

DataSheet_2_IL-17A Increases Doxorubicin Efficacy in Triple Negative Breast Cancer.docx by Nicholas R. Hum (12563075)

“…Furthermore, transcriptional profiles of tumor infiltrated T cells in DOX responsive tumors revealed decreased exhaustion, increased chemokine/cytokine expression, and increased activation and cytotoxic activity. γδ T cell derived IL-17A was identified to be highly abundant in the sensitive tumor microenvironment. …”

Image_3_GM-CSF-activated STAT5A regulates macrophage functions and inflammation in atherosclerosis.png by Jan Nagenborg (14771194)

“…These changes could partially be confirmed at functional level, with significant increases in apoptosis and decreases in lipid uptake and IL-6, IL-8, and TNFa cytokine secretion after STAT5A knockdown. …”

Continuous glucose monitor use with and without remote monitoring in pregnant women with type 1 diabetes: A pilot study by Sarit Polsky (8721450)

“…</p><p>Results</p><p>HbA1c decreased in all groups throughout pregnancy and was significantly lower over time in women using CGM Share (n = 15) compared to CGM Alone (n = 13) or no CGM (n = 8) (p = 0.0042). …”

Image_5_GM-CSF-activated STAT5A regulates macrophage functions and inflammation in atherosclerosis.png by Jan Nagenborg (14771194)

“…These changes could partially be confirmed at functional level, with significant increases in apoptosis and decreases in lipid uptake and IL-6, IL-8, and TNFa cytokine secretion after STAT5A knockdown. …”

DataSheet_1_S100A9 Activates the Immunosuppressive Switch Through the PI3K/Akt Pathway to Maintain the Immune Suppression Function of Testicular Macrophages.docx by Zun Pan Fan (11605789)

“…Treatment with S100A9 and PI3K inhibitor decreased the proportion of M2-type TMs in control and UPEC-infected mouse. …”

DataSheet_1_Lomerizine inhibits LPS-mediated neuroinflammation and tau hyperphosphorylation by modulating NLRP3, DYRK1A, and GSK3α/β.pdf by Jin-Hee Park (732531)

“…Introduction<p>Lomerizine is a calcium channel blocker that crosses the blood–brain barrier and is used clinically in the treatment of migraines. …”

RTA 408, A Novel Synthetic Triterpenoid with Broad Anticancer and Anti-Inflammatory Activity by Brandon L. Probst (727964)

“…Here, we characterized the in vitro antioxidant, anti-inflammatory, and anticancer activities of RTA 408, a novel AIM that is currently being evaluated in patients with advanced malignancies. …”

DataSheet_1_IL-17A Increases Doxorubicin Efficacy in Triple Negative Breast Cancer.pdf by Nicholas R. Hum (12563075)

“…Furthermore, transcriptional profiles of tumor infiltrated T cells in DOX responsive tumors revealed decreased exhaustion, increased chemokine/cytokine expression, and increased activation and cytotoxic activity. γδ T cell derived IL-17A was identified to be highly abundant in the sensitive tumor microenvironment. …”

Image_1_GM-CSF-activated STAT5A regulates macrophage functions and inflammation in atherosclerosis.png by Jan Nagenborg (14771194)

“…These changes could partially be confirmed at functional level, with significant increases in apoptosis and decreases in lipid uptake and IL-6, IL-8, and TNFa cytokine secretion after STAT5A knockdown. …”

HIV-Tat regulates macrophage gene expression in the context of neuroAIDS by Loreto Carvallo (4167607)

“…We found that HIV Tat increased expression of C5, APBA1, and BDNF, and decreased CRLF2. The K50A Tat-mutation dysregulated expression of these genes without affecting the binding of the Tat complex to their gene sequences. …”

Image_2_Rap1 Is Essential for B-Cell Locomotion, Germinal Center Formation and Normal B-1a Cell Population.jpeg by Sayaka Ishihara (538809)

“…In mice having B-cell-specific Rap1a/b double knockouts (DKO), the number of B cells in lymph nodes decreased to approximately 4% of that of control mice, and B cells were present in the spleen and blood. …”

Image_1_Rap1 Is Essential for B-Cell Locomotion, Germinal Center Formation and Normal B-1a Cell Population.jpg by Sayaka Ishihara (538809)

“…In mice having B-cell-specific Rap1a/b double knockouts (DKO), the number of B cells in lymph nodes decreased to approximately 4% of that of control mice, and B cells were present in the spleen and blood. …”

Image_8_GM-CSF-activated STAT5A regulates macrophage functions and inflammation in atherosclerosis.png by Jan Nagenborg (14771194)

“…These changes could partially be confirmed at functional level, with significant increases in apoptosis and decreases in lipid uptake and IL-6, IL-8, and TNFa cytokine secretion after STAT5A knockdown. …”

Table_1_GM-CSF-activated STAT5A regulates macrophage functions and inflammation in atherosclerosis.docx by Jan Nagenborg (14771194)

“…These changes could partially be confirmed at functional level, with significant increases in apoptosis and decreases in lipid uptake and IL-6, IL-8, and TNFa cytokine secretion after STAT5A knockdown. …”

DataSheet_1_Complement C3 and Activated Fragment C3a Are Involved in Complement Activation and Anti-Bacterial Immunity.pdf by Meng Wu (191457)

“…<p>In the complement system, C3 is a central component in complement activation, immune defense and immune regulation. …”