DCB-3503, a Tylophorine Analog, Inhibits Protein Synthesis through a Novel Mechanism by Ying Wang (11406)

“…<div><h3>Background</h3><p>DCB-3503, a tylophorine analog, inhibits the growth of PANC-1 (human pancreatic ductal cancer cell line) and HepG2 (human hepatocellular cancer cell line) tumor xenografts in nude mice. …”

Prenyllongnols A–D, New Prenylated Acylphloroglucinols that Fight Concanavalin A‑Induced Autoimmune Hepatitis by Zhengyi Shi (8978924)

“…Furthermore, in a Con A-challenged autoimmune hepatitis mouse model, the mice in the group that were pretreated with isolate <b>2</b> significantly ameliorated liver injury and decreased proinflammatory cytokine production. …”

RhoA as a signaling hub controlling glucagon secretion from pancreatic α-cells by Xue Wen Ng (13162930)

“…Pharmacological inhibition of RhoA disrupts glucose inhibition of glucagon secretion in islets and decreases cortical F-actin density in dispersed α-cells and α-cells in intact islets.  …”

A 3D Fibrous Scaffold Inducing Tumoroids: A Platform for Anticancer Drug Development by Yvonne K. Girard (471304)

“…<div><p>The development of a suitable three dimensional (3D) culture system for anticancer drug development remains an unmet need. …”

Poly (A) Binding Protein Cytoplasmic 1 Is a Novel Co-Regulator of the Androgen Receptor by Kurtis Eisermann (95302)

“…Co-immunoprecipitation assays confirmed the association of PABPC1 with a.a. 50-250 of the NTD of the AR. Knockdown of PABPC1 decreased nuclear AR protein levels and inhibited androgen activation of the AR target PSA in LNCaP and C4-2 cells. …”

Depletion of RipA results in a reversible arrest in growth of <i>M. smegmatis.</i> by Erik C. Hett (244859)

“…OriE: <i>E. coli</i> origin of replication. (B) <i>ripA</i> depletion strain of <i>M. smegmatis</i> was grown with inducer (Tet), then inoculated into media with decreasing amounts of inducer and followed by OD₆₀₀ over time. …”

Effect of a spray formulation on the reproductive parameters of a susceptible population of Rhipicephalus (Boophilus) microplus by Breno Cayeiro Cruz (5311052)

“…The engorged female weight (days 1 to 7), weight of egg masses (days 5 to 10) and larval hatching percentage (days 5 to 19) were decreased (P ≤ 0.05). It is possible that a formulation can lead to deleterious effects on R. …”

Dry immersion as a model of deafferentation: A neurophysiology study using somatosensory evoked potentials by Blandine Acket (5675420)

“…<div><p>Introduction</p><p>Dry immersion is a ground-based experiment simulating the effects of weightlessness, and it is a model of acute symmetrical bilateral deafferentation. …”

Circulating Serum MicroRNA-130a as a Novel Putative Marker of Extramedullary Myeloma by Lenka Besse (798072)

“…Further, microRNA-130a was decreased in bone marrow plasma cells obtained from patients with extramedullary myeloma in comparison to bone marrow plasma cells of myeloma patients without such manifestation, but it was increased in tumor site plasma cells of patients with extramedullary disease compared to bone marrow plasma cells of such patients (<i>p</i><0.0001). …”

The primary evaluation and characterization of obsolete DDT pesticide from a precalciner of a cement kiln by Yang Li (7082)

“…The release of chlorine reached a peak between 800 °C and 900 °C. It was found that the oxygen content had a positive correlation with the process of dechlorination. …”

Mechanosynthesis of a Coamorphous Formulation of Creatine with Citric Acid and Humidity-Mediated Transformation into a Cocrystal by Kyle B. Pekar (9936319)

“…Creatine is recognized as a dietary staple among athletes, with two supplement formulations currently available on the United States market: creatine monohydrate and creatine hydrochloride. …”

A20 Deficiency in Lung Epithelial Cells Protects against Influenza A Virus Infection by Jonathan Maelfait (181048)

“…This phenotype is not due to decreased viral replication. Instead host innate and adaptive immune responses and lung damage are reduced in A20^AEC-KO mice. …”

Human Papillomavirus Infection in a Male Population Attending a Sexually Transmitted Infection Service by Marta Elena Álvarez-Argüelles (276222)

“…Men play an important role in the transmission of the virus and act as a reservoir. The aim of this study was to determine the HPV-genotypes and their prevalence in a group of men attending a Sexually Transmitted Infection service.…”

Supplementary Material for: Development of a root caries prediction model in a population of dental attenders by Fee P.A. (13545517)

“…However, there is generally no accepted practice to identify individuals at risk of disease. There is a need for the development of a root caries prediction model to support clinicians to guide targeted prevention strategies. …”

Ubiquitin-Specific Peptidase 5, a Target Molecule of Vialinin A, Is a Key Molecule of TNF-α Production in RBL-2H3 Cells by Yasukiyo Yoshioka (492618)

“…<div><p>Tumor necrosis factor alpha (TNF-α), a central mediator of the inflammatory response, is released from basophilic cells and other cells in response to a variety of proinflammatory stimuli. …”

Video_1_In-vitro Characterization of a Hernia Mesh Featuring a Nanostructured Coating.MOV by Giulia Giuntoli (10008728)

“…<p>Abdominal hernia repair is a frequently performed surgical procedure worldwide. …”

<i>CpAphA</i> is a direct target gene of CpMTA1. by Lijiu Zhao (16458996)

“…The black rectangles indicate that m⁶A peaks with significantly decreased m⁶A enrichment in Δ<i>CpMTA1</i> compared to KU80. …”

Table_1_Psychological impacts of intervention to improve a therapeutic garden for older adults with dementia: a case study conducted at a care facility.docx by Chiara Meneghetti (4630843)

“…Passive isolated behaviors related to more impaired baseline cognitive functioning. The case of Mrs. A extended the findings for the whole sample: although her dementia symptoms (apathy, motor disturbances) worsened, she visited the TG more often after the intervention, her social exchanges and active isolated actions increased, and her agitation and wandering decreased.…”

Table_1_Fluorination Induced Donor to Acceptor Transformation in A1–D–A2–D–A1-Type Photovoltaic Small Molecules.DOCX by Ruimin Zhou (1494670)

“…Among the three molecules, the electron mobility is increased while the hole mobility is decreased with increasing fluorination. This work provides a typical example of tuning of the electron donating and withdrawing property without changes to the backbone of the conjugated molecules, which is important for further designing high performance solution processable small molecules.…”

Geographical and Ethnic Distributions of the MTHFR C677T, A1298C and MTRR A66G Gene Polymorphisms in Chinese Populations: A Meta-Analysis by Xingmin Wang (2614936)

“…<div><p>Background</p><p>The geographical and ethnic distributions of the polymorphic methylenetetrahydrofolate reductase (MTHFR) mutations (C677T and A1298C) and methionine synthase reductase (MTRR) mutation (A66G) remain heterogeneous in China. …”