Landscape of Targeted Anti-Cancer Drug Synergies in Melanoma Identifies a Novel BRAF-VEGFR/PDGFR Combination Treatment by Adam A. Friedman (812702)

“…We describe the results of a combination screen of an unprecedented scale in mammalian cells performed using a collection of targeted, clinically tractable agents across a large panel of melanoma cell lines. …”

Data_Sheet_1_Associations of lipids and lipid-lowering drugs with risk of stroke: a Mendelian randomization study.ZIP by Hao Qin (113159)

“…The IVW-MR also found a suggestive evidence that decreased LDL-C levels mediated by the PCSK9 (proprotein convertase subtilisin-kexin type 9) gene were associated with a reduced risk of any stroke (AS) (OR, 1.31; 95% CI, 1.13–1.52; p = 0.0003), any ischemic stroke (AIS) (OR, 1.29; 95% CI, 1.10–1.51; p = 0.001), and LAS (OR, 1.73; 95% CI, 1.15–2.59; p = 0.008), while NPC1L1 (Niemann-Pick C1-like protein)-mediated LDL-C levels were associated with a higher risk of small vessel stroke (SVS) (OR, 6.10; 95% CI, 2.13–17.43; p = 0.0008). …”

Table1_The role of circulating cytokines in heart failure: a bidirectional, two-sample Mendelian randomization study.xlsx by Haoran Zheng (388894)

“…This study draws further conclusions at the genetic level, providing a basis for future large-scale clinical trials.…”

Datasheet1_The role of circulating cytokines in heart failure: a bidirectional, two-sample Mendelian randomization study.pdf by Haoran Zheng (388894)

“…This study draws further conclusions at the genetic level, providing a basis for future large-scale clinical trials.…”

DataSheet_1_Cascading effects of seed-stem-individual spatial patterns along a grazing gradient.docx by Zhou Qin-Yuan (14792533)

“…The results showed the following: (1) Seed size increased with increasing grazing intensity, and the coefficient of variation for seed size and seed number in the heavy grazing treatment was greater than 0.6. (2) The structural equation model showed that grazing treatment had a positive effect on seed number, seed size and reproductive stem number and a negative effect on reproductive stem weight. (3) Grazing treatment did not affect the resource allocation to reproductive stems and vegetative stems per unit length of reproductive K. humilis individuals. (4) Compared with the number of reproductive individuals in the no grazing treatment, the number in the heavy grazing treatment decreased significantly, and the negative correlation between reproductive individuals and nonreproductive individuals changed from a full-scale negative correlation to a small-scale negative correlation and a large-scale positive correlation. …”

Data Sheet 1_Causality of genetically determined glucosamine supplementation on cognition and sarcopenia: a Mendelian randomization study.docx by Yi Kang (387134)

“…Background<p>Evidence indicates a negative link between glucosamine and age-related cognitive decline and sarcopenia. …”

S1 Data - Adaptive integrated intervention approaches for schistosomiasis elimination in Pemba: A 4-year intervention study and focus on hotspots by Lydia Trippler (10136316)

The impact of the interaction between PAC and CPAM dosage on sewage turbidity. (a) Contour diagram; (b) 3D surface diagram. by Peng Zhao (128233)

HIFN protection of vision loss is Trk-B dependent: (A) Schematic representation of the experimental protocol of ANA-12 and HIFN treatment. by Shweta Modgil (12864344)

Deletion of <i>bipA</i> in pathogenic <i>S</i>. Typhimurium strains resulted in reduced invasion into HCT116 cells. by Eunsil Choi (8271039)

Establishment and differentiation into neurons of iPSC line BIONi010-C-24 with doxycycline inducible A53T α-synuclein. by Charlotte Vajhøj (11864270)

S2 Data - Adaptive integrated intervention approaches for schistosomiasis elimination in Pemba: A 4-year intervention study and focus on hotspots by Lydia Trippler (10136316)

Reduced swarming motility and flagellin production in <i>bipA</i>-deleted <i>S.</i> Typhimurium strains at low temperatures. by Eunsil Choi (8271039)

RTL8 levels are low in cell lines with high VLP abundance, and high in a cell line with low VLP yield. by Will Campodonico (20485651)

Dilution coefficient (τ) at 25°C and 37°C for 5 suspending media compared to that of a physiological value of τ = 1. by Chadapust J. Sudsiri (14670602)

Water intake and drinking behaviour in Nellore steers with (+S) and without (-) access to shade finished in feedlot during spring in a tropical environment. by M. Jordana Rivero (14610947)

Event frequencies and Kaplan-Meier estimates for (A) hepatocellular carcinoma and (B) overall mortality in patients with autoimmune hepatitis and matched controls. by Jihye Lim (5832089)

Growth and stationary phase survival of the wild-type strain ATCC14028 and Δ<i>corA</i> mutant in LB. by Selma Metaane (12329248)

The Δ<i>corA</i> mutation impairs kinetics of cell growth in the absence of <i>phoP</i> only. by Selma Metaane (12329248)

The percentage of DPPH^• (A) and ABTS^•+ (B) inhibition of 6-shogaol-rich ginger extract and Trolox. by Hataichanok Chuljerm (19144293)