A synthetic lethal screen identifies the Vitamin D receptor as a novel gemcitabine sensitizer in pancreatic cancer cells by V Bhattacharjee (681247)

“…Indeed, these treatment regimens have only extended patient survival by a few months. The complex microenvironment of PCa tumors has been shown to complicate drug delivery thus decreasing the sensitivity of PCa tumors to chemotherapy. …”

Assessing the efficacy of a modified crushing technique for the management of concha bullosa: a cone beam computer tomography study by Alireza Mesbahi (14224544)

“…Results: Twenty-four cases of obstructive concha bullosa were included in this study with 13 short-term and 11 long-term follow-ups. All patients showed a significantly decreased postoperative CB size (p< 0.001). …”

B6 <i>mA3</i> is a saturable innate restriction factor <i>in vivo</i>. by Diana S. Smith (176104)

“…(B) Noninfectious FV release despite decreased <i>mA3</i> restriction. Plasma viral loads (<i>Left</i>) and virion infectivity (<i>right</i>) were determined for mice infected with 500 SFFU of FV. …”

A Human Multi-Epitope Recombinant Vaccinia Virus as a Universal T Cell Vaccine Candidate against Influenza Virus by Alan G. Goodman (202321)

“…Upon challenge with influenza virus, the vaccinated mice exhibited decreased viral load in the lungs and a delay in mortality. …”

Identification of Cellular Calcium Binding Protein Calmodulin as a Regulator of Rotavirus A Infection during Comparative Proteomic Study by Shiladitya Chattopadhyay (148442)

Supplementary Material for: Neovascular Maculopathy after laser 2RT in a Young Myopic Patient: A Case Report by figshare admin karger (2628495)

“…Introduction Laser photobiomodulation, including 2RT (Retinal Rejuvenation Therapy), is a system which selectively targets the retinal pigment epithelium (RPE) by a concise 3 ns pulse duration. …”

Development of a Highly Potent Analogue and a Long-Acting Analogue of Oxytocin for the Treatment of Social Impairment-Like Behaviors by Wataru Ichinose (1895173)

“…The nonapeptide hormone oxytocin (OT) has pivotal brain roles in social recognition and interaction and is thus a promising therapeutic drug for social deficits. …”

Substituting polyunsaturated fat for saturated fat: A health impact assessment of a fat tax in seven European countries by Johanna-Katharina Schönbach (6940391)

“…For each country, we created a fat tax scenario with a decreased SFA intake and a corresponding increase in PUFA. …”

Distribution pattern of 6mA in the genomic DNA of <i>A</i>. <i>ferrooxidans</i> ATCC 23270. by RuTao Lin (17896476)

“…(C) Distribution pattern of 6mA peaks around the TSS in <i>A</i>. <i>ferrooxidans</i> ATCC 23270 under Fe²⁺ (top panel) and RISCs (bottom panel) oxidizing conditions. 6mA levels decreased at the TSS, followed by a sharp increase immediately after the TSS under both conditions.…”

Differential filtering of somatic and dendritic input persists for a variety of cell morphologies and a gradual distribution of the active current. by Ekaterina Zhuchkova (480350)

“…<i>b</i>: Tapering of diameter towards the dendritic end (dendrite diameter gradually decreases from m to m). <i>c</i>: Neuron with two dendrites, both with the same parameters as model <i>a</i>. …”

Impact of the fear of Covid-19 infection on intent to breastfeed; a cross sectional survey of a perinatal population in Qatar by Reagu, Shuja Mohd

“…This study attempts to explore any relationship between the Covid-19 pandemic and perinatal obsessive-compulsive symptomatology and whether the Covid-19 pandemic has any impact on intent to breastfeed. Methods: A cross sectional survey of perinatal women attending largest maternity centre in Qatar was carried out during the months of October to December 2020. …”
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Exposure to Low-Dose Bisphenol A Impairs Meiosis in the Rat Seminiferous Tubule Culture Model: A Physiotoxicogenomic Approach by Sazan Ali (624519)

“…<div><p>Background</p><p>Bisphenol A (BPA) is one of the most widespread chemicals in the world and is suspected of being responsible for male reproductive impairments. …”

“From the Edge to the Center”: Viscoelastic Migration of Particles and Cells in a Strongly Shear-Thinning Liquid Flowing in a Microchannel by Francesco Del Giudice (4585036)

“…When inertia is negligible, numerical simulations have shown that strongly shear-thinning polymer solutions (fluids with a shear viscosity that decreases with increasing flow rates) promote transversal migration of particles and cells toward the corners or toward the centerline in a straight microchannel with a square cross section, as a function of particle size, cell deformability, and channel height. …”

A Comparative Study of Neural and Mesenchymal Stem Cell-Based Carriers for Oncolytic Adenovirus in a Model of Malignant Glioma by Atique U. Ahmed (226456)

“…Loading oncolytic adenovirus into NSCs and MSCs also led to expression of both pro- and anti-inflammatory genes and decreased vector-mediated neuroinflammation. Our results indicate that, despite possessing a comparable migratory capacity, NSCs display superior therapeutic efficacy in the context of intracranial tumors. …”

Salvianolic Acid A, a Novel Matrix Metalloproteinase-9 Inhibitor, Prevents Cardiac Remodeling in Spontaneously Hypertensive Rats by Baohong Jiang (207398)

“…Moreover, SalA treatment in SHR resulted in decreased heart fibrosis and attenuated heart hypertrophy. …”

Tall wheatgrass response toward phosphorus deficiency: a constraint to its use as a forage resource in marginal soils by Eduardo Jorge Ochner (18604764)

“…In this work we hypothesize that tall wheatgrass is a plant more sensitive to low P availability than commonly assumed. …”

Effects of a vegetarian diet combined with exercise on lipid profiles and blood pressure: A systematic review and meta-analysis by Yanlong Niu (13801054)

“…A literature search was conducted in electronic databases from build to February 27, 2022. …”

A Meal Detection Algorithm for the Artificial Pancreas: A Randomized Controlled Clinical Trial in Adolescents With Type 1 Diabetes by Emilie Palisaitis (9556686)

“…<a><b>Background</b>: We developed a meal detection algorithm for the artificial pancreas that detects unannounced meals and delivers an automatic insulin bolus.…”

Complementation of fHbp NspA double mutants with NspA restores fH binding and serum resistance. by Lisa A. Lewis (244867)

“…Error bars indicate standard deviation calculated from 3 independent experiments. With 1.5% NHS the decreased survival observed in strains that lack NspA was statistically significant (P<0.02 by a t-test) compared to the parent strain expressing both NspA and fHbp.…”

Effect of a Er, Cr:YSGG laser and a Er:YAG laser treatment on oral biofilm-contaminated titanium by So-Hyun Park (1604836)

“…<div><p>Abstract Implant surface decontamination is a challenging procedure for therapy of peri-implant disease. …”