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35901
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35902
Manhattan plot that shows the location of genes involved in folate, homocysteine, and transsulfuration pathways for which we observed, from hybrid analyses, a significantly decreased risk of obstructive heart defects when the risk variant was paternally-derived compared to maternally-derived, The National Birth Defects Prevention Study, USA, October 1997–August 2008 births.
Published 2021“…<p>Manhattan plot that shows the location of genes involved in folate, homocysteine, and transsulfuration pathways for which we observed, from hybrid analyses, a significantly decreased risk of obstructive heart defects when the risk variant was paternally-derived compared to maternally-derived, The National Birth Defects Prevention Study, USA, October 1997–August 2008 births.…”
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35903
CDK5 knockdown increases TP53 and p27<sup>Kip1</sup> protein half-lives, increases nuclear localization of the two proteins, decreases p27<sup>Kip1</sup> p-T187 phosphorylation and induces p21<sup>Cip1</sup> in a TP53-dependent manner.
Published 2015“…<p>(<b>A</b>) Transfection with CDK5 siRNA increased the half-life of p53 and p27<sup>Kip1</sup> protein. …”
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35904
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35905
Numerical simulation results of the seepage flow field for the Wangjiapo landslide under different rain patterns: (a)–(d) illustrate the pore water pressure distribution under uniform rainfall, decreasing rainfall, incremental rainfall, and single-peak rainfall, respectively; (e)–(h) present the pore water pressure time-history curves corresponding to the four rain patterns.
Published 2025“…<p>Numerical simulation results of the seepage flow field for the Wangjiapo landslide under different rain patterns: (a)–(d) illustrate the pore water pressure distribution under uniform rainfall, decreasing rainfall, incremental rainfall, and single-peak rainfall, respectively; (e)–(h) present the pore water pressure time-history curves corresponding to the four rain patterns.…”
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35906
Increasing proportions of HIV-1 non-B subtypes and of NNRTI resistance between 2013 and 2016 in Germany: Results from the national molecular surveillance of new HIV-diagnoses - Fig...
Published 2018“…(B) Trend analysis for major subtypes that show a significant increase or decrease (p < 0.05) between 2013 and 2016. …”
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35907
SPI-1 virulence gene expression change in WT <i>Salmonella</i> upon treatment with 1 mM indole.
Published 2018“…Data shown are the mean fold decrease in expression (n = 3) with indole-treatment relative to the solvent-treated control at a significance level of <i>p</i> < 0.05 using the Student’s <i>t</i>-test. …”
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35908
Effect of indole in combination with cecal SCFAs on <i>hilA</i> expression.
Published 2018“…Data shown are the mean fold decrease (n = 3) in expression of <i>hilA</i> with treatment relative to the control: <i>hilA</i> expression in presence of 200 mM NaCl. * denotes statistical significance relative to cecal SCFAs alone at <i>p</i> < 0.05 using the Student’s <i>t</i>-test. …”
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35909
Table1_Predicting chronic responses to calcium channel blockade with a virtual population of African Americans with hypertensive chronic kidney disease.XLSX
Published 2024“…Both clinical evidence (the African American Study of Kidney Disease and Hypertension, or AASK trial) and experimental studies have demonstrated that CCB may expose glomerular capillaries to high systemic pressures and exacerbate CKD progression. Therefore, using a large physiological model, we set out to replicate the AASK trial findings, predict renal hemodynamic responses and the role of the renin-angiotensin system during CCB antihypertensive therapy in a virtual population, and hypothesize mechanisms underlying those findings. …”
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35910
Naturally Occurring Autoantibodies against Tau Protein Are Reduced in Parkinson's Disease Dementia
Published 2016“…</p><p>Conclusion</p><p>We detected a significantly decreased nAbs-tau serum level in PDD patients, indicating a potential linkage between nAbs-tau serum titer and cognitive deficits in PD. …”
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35911
Data_Sheet_1_Ischemic stroke and sarcopenia have an asymmetric bidirectional relationship based on a two-sample Mendelian randomization study.docx
Published 2024“…</p>Conclusion<p>This study demonstrates that a reduction in ALM and right-hand grip strength is associated with SVS, whereas decreased ALM may serve as a protective factor against CES. …”
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35912
Table 3_Nonlinear relationship between fibrinogen-to-albumin ratio and mortality in critically ill patients with sepsis: a retrospective cohort study.xlsx
Published 2025“…</p>Results<p>In our analysis of 4,615 sepsis patients, we observed that mortality risk initially decreased with increasing FAR values, reaching a minimum at approximately 94.5*10<sup>−3</sup>, before rising again. …”
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35913
Table 1_Nonlinear relationship between fibrinogen-to-albumin ratio and mortality in critically ill patients with sepsis: a retrospective cohort study.xlsx
Published 2025“…</p>Results<p>In our analysis of 4,615 sepsis patients, we observed that mortality risk initially decreased with increasing FAR values, reaching a minimum at approximately 94.5*10<sup>−3</sup>, before rising again. …”
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35914
Image_1_Association Between Hormone Replacement Therapy and Development of Endometrial Cancer: Results From a Prospective US Cohort Study.TIF
Published 2022“…<p>Although hormone replacement therapy (HRT) use is associated with elevated endometrial cancer(EC) risk, little evidence assesses potential effect-modifiers on HRT-related EC in a long-term follow-up. In this large-scale longitudinal cohort study, we tried to evaluate the association between different HRT types/methods use and risk of EC, and reveal this risk within different body mass index (BMI) groups. …”
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35915
Table1_A real-world disproportionality analysis of Tivozanib data mining of the public version of FDA adverse event reporting system.xlsx
Published 2024“…However, comprehensive evaluation of its long-term safety profile in a large sample population remains elusive. The current study assessed Tivozanib-related adverse events of real-world through data mining of the US Food and Drug Administration Adverse Event Reporting System FDA Adverse Event Reporting System.…”
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35916
Table 2_Nonlinear relationship between fibrinogen-to-albumin ratio and mortality in critically ill patients with sepsis: a retrospective cohort study.xlsx
Published 2025“…</p>Results<p>In our analysis of 4,615 sepsis patients, we observed that mortality risk initially decreased with increasing FAR values, reaching a minimum at approximately 94.5*10<sup>−3</sup>, before rising again. …”
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35917
<i>Cryptococcus</i>. <i>neoformans</i> incubated for 8 days in hypoxia were intact with a low stress response and delayed growth.
Published 2019“…<p><b>A</b>. Cells recovered after 8 days in hypoxia (8D-HYPOx) were compared to those incubated in normoxia (8D-NORMOx), to stationary phase (STAT = D0) cells. …”
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35918
Table 4_Nonlinear relationship between fibrinogen-to-albumin ratio and mortality in critically ill patients with sepsis: a retrospective cohort study.xlsx
Published 2025“…</p>Results<p>In our analysis of 4,615 sepsis patients, we observed that mortality risk initially decreased with increasing FAR values, reaching a minimum at approximately 94.5*10<sup>−3</sup>, before rising again. …”
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35919
Table1_Effect of inflammatory cytokines and plasma metabolome on OSA: a bidirectional two- sample Mendelian randomization study and mediation analysis.pdf
Published 2024“…</p>Methods<p>We conducted a large-scale study using data from the FinnGen database, with 43,901 cases and 366,484 controls for our discovery MR analysis. …”
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35920
Data_Sheet_1_Ischemic stroke and sarcopenia have an asymmetric bidirectional relationship based on a two-sample Mendelian randomization study.docx
Published 2024“…</p>Conclusion<p>This study demonstrates that a reduction in ALM and right-hand grip strength is associated with SVS, whereas decreased ALM may serve as a protective factor against CES. …”