(A-E) The lead compound can bind to mouse Dnmt3a (PDB: 4U7P ref [18]). by Vedran Miletić (3918584)

“…(<u><b>E</b></u>) The plots show changes in pulling force and the corresponding decrease in the number of dynamic binding interactions within Dnmt3a-inhibitor complex. …”

Kaplan–Meier estimate for quintiles (Q1–Q5, highest) of the apoB/apoA-1 ratio (apo-ratio) for major adverse cardiovascular events in men and women. by Göran Walldius (286838)

Pig FUT3-AS1 is identified as a host lncRNA involved in <i>E</i>. <i>coli</i> F18 infection based on RNA-Seq analysis. by Zhengchang Wu (140532)

Violin plots for the herd immunity threshold as estimated for the social distancing scenario, when investigating infectiousness-related heterogeneity (in green, panel a) and contac... by Elise J. Kuylen (13282013)

Decoupling the K2 gene cluster over two expression vectors obviates the requirement of RmpA for K2 polysaccharide expression in <i>E</i>. <i>coli</i>. by Paeton L. Wantuch (1667614)

Proportion of time spent in the Start Room or Avoidance Room or showing a behaviour (Stimulus Contact) presented across stimuli and separately for female (n = 10) and male (n = 10)... by Sara Hintze (3216885)

Safranin O fast green staining results of cartilage tissue in different groups of rat PTOA (A: normal group, B: mild PTOA group, C: severe PTOA group). by Peng-fei Han (694841)

ST2+ KLRG-1+ Tregs from <i>T</i>. <i>cruzi</i> infected mice exhibit a phenotype compatible with <i>bona fide</i> trTregs. by Santiago Boccardo (5927954)

Image_2_Biphasic response of human iPSC-derived neural network activity following exposure to a sarin-surrogate nerve agent.JPEG by Chandrakumar Bogguri (11621443)

“…Regardless of the NIMP concentration, at a network level, communication or coordination of neuronal activity decreased as early as 60 min and persisted at 24 h of NIMP exposure. …”

Assessment of a prognostic model, PSA metrics and toxicities in metastatic castrate resistant prostate cancer using data from Project Data Sphere (PDS) by Bethany Pitcher (3396329)

“…Using data from PDS, we aimed to 1) validate a contemporary prognostic model (Templeton et al., 2014) 2) evaluate prognostic impact of concomitant medications and PSA decrease 3) evaluate factors associated with docetaxel toxicity.…”

DataSheet1_Can Hydrocarbon Extraction From the Crust Enhance or Inhibit Seismicity in Tectonically Active Regions? A Statistical Study in Italy.ZIP by Alexander Garcia (561578)

“…We implemented a large-scale analysis aiming at tracking significant departures of background seismicity from a stationary behavior around active oil and gas development leases in Italy. …”

Image_3_Biphasic response of human iPSC-derived neural network activity following exposure to a sarin-surrogate nerve agent.JPEG by Chandrakumar Bogguri (11621443)

“…Regardless of the NIMP concentration, at a network level, communication or coordination of neuronal activity decreased as early as 60 min and persisted at 24 h of NIMP exposure. …”

The impact of potentially inappropriate medication on the development of health care costs and its moderation by the number of prescribed substances. Results of a retrospective mat... by Dirk Heider (784782)

“…The average effect of one additionally prescribed substance (other than PIM) on total health care costs was increased by an amount of 137 € for those being exposed to a PIM. In quarters 2–4 of the post-period, the differences between both study groups tended to decrease sequentially.…”

Data_Sheet_1_A scoping review of electroencephalographic (EEG) markers for tracking neurophysiological changes and predicting outcomes in substance use disorder treatment.docx by Tarik S. Bel-Bahar (13967229)

“…<p>Substance use disorders (SUDs) constitute a growing global health crisis, yet many limitations and challenges exist in SUD treatment research, including the lack of objective brain-based markers for tracking treatment outcomes. …”

Image_1_Biphasic response of human iPSC-derived neural network activity following exposure to a sarin-surrogate nerve agent.JPEG by Chandrakumar Bogguri (11621443)

“…Regardless of the NIMP concentration, at a network level, communication or coordination of neuronal activity decreased as early as 60 min and persisted at 24 h of NIMP exposure. …”

Cellular and Matrix Response of the Mandibular Condylar Cartilage to Botulinum Toxin by Eliane H. Dutra (3207312)

“…There was no significant difference in the mandibular length and condylar head length; however, the condylar width was significantly decreased after Botox injection. Our histology showed decreased numbers of Col10a1 expressing cells, decreased cell proliferation and increased cell apoptosis in the subchondral bone and mandibular condylar cartilage, decreased TRAP activity and mineralization of Botox injected side cartilage and subchondral bone. …”

Data_Sheet_1_A Multiomic Approach to Investigate the Effects of a Weight Loss Program on the Intestinal Health of Overweight Horses.ZIP by Nicola Walshe (10989768)

“…Obesity in companion animals is also a common clinical problem. We set out using a multidimensional approach, to determine the effectiveness and safety of a weight loss program for horses incorporating diet restriction and exercise. …”

Clinical endpoints in the controlled human challenge model for <i>Shigella</i>: A call for standardization and the development of a disease severity score by Chad K. Porter (2552560)

“…An ordinal disease score characterizing the breadth of disease severity may enable a better characterization of shigellosis and can decrease sample size requirements. …”

Use of a platelet-rich plasma-collagen scaffold as a bioenhanced repair treatment for management of partial cruciate ligament rupture in dogs by Susannah J. Sample (308203)

“…This study tested the hypothesis that treatment of partial stable CR stifles with an intra-articular collagen scaffold and PRP would decrease the disease progression, synovitis and risk of complete CR over a 12-month study period. …”

Potential interplay between Aβ oligomers, Ca²⁺, and a target cell in the initial stages of Alzheimer's disease. by Anna Itkin (354170)

“…Aβ oligomers can affect surface expression of N-methyl-D-aspartate receptors (NMDARs) <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0018250#pone.0018250-Dewachter1" target="_blank">[67]</a>, may increase <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0018250#pone.0018250-Molnr1" target="_blank">[68]</a> or decrease the conductance <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0018250#pone.0018250-Shankar1" target="_blank">[69]</a>, and facilitate long-term synaptic depression by disrupting neuronal glutamate uptake <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0018250#pone.0018250-Li1" target="_blank">[70]</a>.…”