Illustration of simulation procedure for a 4-AFC paradigm. by Kathleen Vancleef (343934)

“…Each staircase (B) follows the rules described in the main text: starting at 3 log₁₀ arcsec, decreasing the disparity by 0.15 log₁₀ arcsec after a correct answer and increasing disparity by 0.45 log₁₀ arcsec after an incorrect answer. …”

Glasslike Membrane Protein Diffusion in a Crowded Membrane by Ignacio Munguira (1434316)

“…Furthermore, around solid-like patches and immobile molecules a slower glass phase is detected leading to protein trapping and creating a perimeter of decreased membrane diffusion.…”

Experimental Evolution of a Novel Sexually Antagonistic Allele by Rebecca Dean (109545)

“…In sexually reproducing organisms, sex-specific optima mean that the same allele can have sexually antagonistic expression, i.e. beneficial in one sex and detrimental in the other, a phenomenon known as intralocus sexual conflict. …”

A279T inhibits proliferation of esophageal cancer cells. by Yuwei Zhang (388956)

“…Immunofluorescence analysis (left panel) with corresponding summary (right panel) of Ki67 expression in esophageal cancer cells expressing wtTERT or A279T (Red: Ki67; blue: DAPI). EsC1 and EsC2 cells expressing A279T exhibit decreased Ki67 levels relative to respective cells expressing wtTERT. …”

A regulatory gene network of foam-cell formation. by Josefin Skogsberg (88384)

“…CE accumulation (given as average percentage next to each node) was decreased (blue) by siRNA inhibition of 5 genes and increased (red) by inhibition of 2 genes; inhibition of 1 gene had no effect (black) (see also <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000036#pgen-1000036-t003" target="_blank">Table 3</a>). …”

Preemptive analgesia in orthopedic surgery: a literature review by Juan Lopez Valencia (4715691)

“…Reducing postoperative pain will result in more patient satisfaction, less complications due to immobility and decreased hospitalization periods. In this review, the use of preemptive analgesia in orthopedic surgery with a great variety of medications and interventions is examined. …”

A systematic review on the impact of alcohol warning labels by Joyce, Kayla M.

“…Findings on the effects of alcohol warning labels (AWLs) as a harm reduction tool have been mixed. This systematic review synthesized extant literature on the impact of AWLs on proxies of alcohol use. …”
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Microbiota and Metabolome Associated with Immunoglobulin A Nephropathy (IgAN) by Maria De Angelis (468661)

“…<div><p>This study aimed at investigating the fecal microbiota, and the fecal and urinary metabolome of non progressor (NP) and progressor (P) patients with immunoglobulin A nephropathy (IgAN). Three groups of volunteers were included in the study: (i) sixteen IgAN NP patients; (ii) sixteen IgAN P patients; and (iii) sixteen healthy control (HC) subjects, without known diseases. …”

LDN-193189 is a strong and direct inhibitor of chondrogenesis. by Sayantani Sinha (716150)

“…<p>(<b>A-J</b>) Alcian blue staining and optical quantification of mouse embryo limb bud cell micromass cultures on day 4 and 6 reared in control medium (A and F) or medium containing rhBMP2 (B and G), LDN (C and H) or rhBMP2 plus LDN (D and I). …”

CypE inhibits influenza A virus replication. by Zengfu Wang (208326)

“…<p>(A–D) As described in the <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0022625#s4" target="_blank">Materials and Methods</a>, 293T cells were transfected with si-CypE, Myc-CypE, or Myc-CypE Δ136–187 plasmid and then infected with influenza virus A/WSN/33 at an MOI of 0.1. …”

Economic viability of a RPPU150 (Thousands USD). by Francisco Ernesto Martínez-Castañeda (18530750)

“…Similarly, the probability of obtaining negative net income decreased from 40% in 2022 to 18% in 2026. The technological, productive, and economic management of the production unit allowed for a favorable scenario within the planning horizon. …”

Imidazo[1,2-a]quinoxaline inhibits proliferation by Liyuan Luo (10997496)

“…<p><a>Malignant gliomas having high incidence and mortality rate are diagnosed as the primary brain tumors worldwide. …”

Regulation of T6SS2 genes by AphA. by Li Wang (15202)

“…If there was the association of His-AphA and target DNA, the band of free DNA disappeared with increasing amounts of His-AphA, resulting in a retarded DNA band with decreased mobility, which presumably represented the DNA-AphA complex. …”

Merlin Is a Negative Regulator of Human Melanoma Growth by Lucas B. Murray (143779)

“…<div><p>Merlin is encoded by the neurofibromatosis type 2 (<em>NF2</em>) gene and is a member of the Band 4.1 protein family. This protein acts as a linker that connects cell surface proteins to the actin cytoskeleton. …”

Graph Theoretical Model of a Sensorimotor Connectome in Zebrafish by Michael Stobb (164263)

“…<div><p>Mapping the detailed connectivity patterns (connectomes) of neural circuits is a central goal of neuroscience. The best quantitative approach to analyzing connectome data is still unclear but graph theory has been used with success. …”

Phenotype of CB-NK cells cultured with aAPCs. by Nina Shah (293248)

“…By median fluorescence intensity (MFI), aAPC-expanded CB-NK demonstrated a decreased surface expression of the NCRs NKp30, NKp46 and NKp44. …”

Analytical pairwise comparison of i(A)CG strategies. by Anton M. Unakafov (5706560)

“…Solid-line invasion thresholds show the stable equilibrium fraction which allows coexistence of both strategies (see “<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1007588#sec008" target="_blank">Methods</a>”). …”

A pooled analysis of the association between sarcopenia and osteoporosis by Zhaowei Teng (10179755)

“…Sarcopenia was significantly associated with a greater risk of osteoporosis (OR, 3.10; 95% CI, 2.27–4.23), and each standard deviation increase in relative appendicular skeletal muscle mass was significantly associated with a decreased risk of osteoporosis (OR, 0.64; 95% CI, 0.61–0.67). …”

A Bioenergetic Basis for Membrane Divergence in Archaea and Bacteria by Víctor Sojo (613931)

“…Pumping protons across leaky membranes offers no advantage, even when permeability is decreased 1,000-fold. We hypothesize that a sodium-proton antiporter (SPAP) provided the first step towards modern membranes. …”

Transient Pinning and Pulling: A Mechanism for Bending Microtubules by Ian A. Kent (3179607)

“…<div><p>Microtubules have a persistence length of the order of millimeters <i>in vitro</i>, but inside cells they bend over length scales of microns. …”