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38501
Effects of microRNA-27 (miR-27)a and miR-27b mimics on peroxisome-proliferator activated receptor-γ (PPARγ), CCAAT/enhancer binding protein (C/EBP)α, and C/EBPβ mRNA expression in...
Published 2019“…<p>(A, B) mRNA levels of PPARγ and C/EBPα were increased on day 10 of adipogenesis, and significantly decreased in GO orbital fibroblasts transfected with miR-27a and miR-27b mimics. …”
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38502
Changes in disease burden in Poland between 1990–2017 in comparison with other Central European countries: A systematic analysis for the Global Burden of Disease Study 2017
Published 2020“…For both YLLs and YLDs, greater relative declines were observed for females. There was a large decrease in communicable, maternal, neonatal, and nutritional disease DALYs (48.2%; 46.3–50.4). …”
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38503
The Potential Impact of Pre-Exposure Prophylaxis for HIV Prevention among Men Who Have Sex with Men and Transwomen in Lima, Peru: A Mathematical Modelling Study
Published 2012“…The impact of PrEP is reduced if those on PrEP decrease condom use, but only extreme behaviour changes among non-adherers (over 80% reduction in condom use) and a low PrEP conditional efficacy (40%) would adversely impact the epidemic. …”
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38504
<i>C</i>. <i>difficile mviN</i> impacts cell-surface moieties.
Published 2016“…The ramp in (A) indicates increasing to decreasing concentration from left to right, UD is “undiluted,” and the scale bar in (B) represents 10μm.…”
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38505
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38506
A Patient with IDH2 Mutant Dedifferentiated Chondrosarcoma Demonstrates a Drop in D-2HG Plasma and Urine Levels after Surgical Resection.
Published 2015“…D: D-2HG levels measured in patient plasma samples showed a decrease after surgical resection. E: D-2HG levels measured in patient urine samples showed a decrease after surgical resection. …”
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38507
The Flavone Luteolin Suppresses SREBP-2 Expression and Post-Translational Activation in Hepatic Cells
Published 2015“…Sterol regulatory element binding protein (SREBP) -2 is a key transcription factor in cholesterol metabolism, and <i>HMGCR</i> is a target gene of SREBP-2. …”
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38508
Proposed mechanism of Epac and PKA pathways in GPER-mediated porcine coronary artery relaxation signaling.
Published 2017“…Epac activates Rap1, then RhoA is phosphorylated at serine 188 by both Rap1 signaling and PKA, thereby the activity RhoA and its effector Rho Kinase (ROCK) is inhibited, Reduced Rho kinase activity removes its inhibitory effects on MLCP by decreasing the phosphorylation of MYPT1 (pThr853), the myosin phosphatase target subunit 1 of MLCP, leading to decreased phosphorylation of MLC20 and coronary artery relaxation.…”
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38509
MicroRNA-27 (miR-27)a and miR-27b expression during adipogenesis in Graves’ orbitopathy orbital fibroblasts.
Published 2019“…<p>(A) The levels of miR-27a and (B) miR-27b were gradually decreased upon adipogenic differentiation. …”
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38510
MiR-126-3p overexpression inhibits the migration of thyroid cancer cells.
Published 2015“…<p>Wound healing assay <b>(A)</b> and Boyden chamber assay <b>(B)</b> data. …”
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38511
miR-126-3p reduces VEGF secretion and endothelial tube formation.
Published 2015“…<p><b>(A)</b> miR-126-3p overexpression significantly reduced secreted VEGF levels in TPC-1 and FTC-133 cell lines but not XTC-1 cells. * p < 0.5. …”
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38512
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38513
NSP1 affects host-cell transcription of immune-related genes via H3K9me2.
Published 2024“…<p><b>A</b>.) Meta-analysis of the distribution of PolII associated chromatin (obtained by PolII ChIP-seq) relative to genomic coordinates of protein-coding genes (TSS, Transcription Start Site; TES, Transcription End Site). …”
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38514
Effects of microRNA-27 (miR-27)a and miR-27b mimics on peroxisome-proliferator activated receptor-γ (PPARγ), CCAAT/enhancer binding protein (C/EBP)α, and C/EBPβ protein release in...
Published 2019“…(B) Protein levels of C/EBPα, (C) C/EBPβ and (D) PPARγ were increased on 10 day of adipogenesis and significantly decreased in orbital fibroblasts that were transfected with miR-27a and miR-27b mimics (*P<0.05). …”
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38515
Table_2_Alteration of m6A epitranscriptomic tagging of ribonucleic acids after spinal cord injury in mice.xlsx
Published 2022“…In addition, we found that the m<sup>6</sup>A “writer,” METTL3, significantly decreased after SCI in mice. …”
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38516
Table_3_Alteration of m6A epitranscriptomic tagging of ribonucleic acids after spinal cord injury in mice.xlsx
Published 2022“…In addition, we found that the m<sup>6</sup>A “writer,” METTL3, significantly decreased after SCI in mice. …”
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38517
Table_4_Alteration of m6A epitranscriptomic tagging of ribonucleic acids after spinal cord injury in mice.docx
Published 2022“…In addition, we found that the m<sup>6</sup>A “writer,” METTL3, significantly decreased after SCI in mice. …”
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38518
Table_1_Alteration of m6A epitranscriptomic tagging of ribonucleic acids after spinal cord injury in mice.xlsx
Published 2022“…In addition, we found that the m<sup>6</sup>A “writer,” METTL3, significantly decreased after SCI in mice. …”
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38519
Image_1_Alteration of m6A epitranscriptomic tagging of ribonucleic acids after spinal cord injury in mice.pdf
Published 2022“…In addition, we found that the m<sup>6</sup>A “writer,” METTL3, significantly decreased after SCI in mice. …”
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38520
5-Aza-2’-deoxycytidine in the medial prefrontal cortex regulates alcohol-related behavior and Ntf3-TrkC expression in rats - Fig 4
Published 2017“…<p>(A) Schematic illustrations and representative photomicrographs of the intracranial cannula infusion sites in the mPFC. 5-Aza-dc infusion decreased alcohol intake (B) and alcohol preference (C) in alcohol-exposure rats, corresponding to the reduced blood alcohol levels (F). …”