A proposed molecular mechanism for HTR2B antagonism to prevent heritable PAH. by James D. West (849663)

“…Antagonism of HTR2B inhibits the translocation of SRC and decreases SRC signaling, causing a decrease in expression of SRC regulated genes. …”

Erythroid/Gata1 precursors are affected by <i>csrnp1a</i> knockdown. by Jaime Espina (106906)

“…At 8 somite stage the expression of the erythroid marker <i>klf4</i> was not affected in morphant embryos (A, B) (100%, n = 48). However a clear decrease in <i>gata1</i> expression was detected in <i>csrnp1a</i> deficient embryos (compare C with D) (54,8%; n = 23/42) without major changes in the number of <i>myoD</i> stripes (7,1%; n = 3/42, more than 2 stripes), which served as readout of developmental progression. …”

Perfusion-weighted FREE map of a 78-year-old patient with an acute stroke. by Julian Glandorf (9928451)

“…<p>A bSSFP sequence at 1.5T with a flip angle of 55°. …”

Let-7a interacts with the 3′-untranslated region (UTR) of integrin β3. by Wei-Min Liu (1527772)

“…Semi-quantitative analysis of integrin-β3 expression levels in the embryos. There was a significant decrease in integrin-β3 protein expression in embryos eclectroporated with pre-let-7a relative to the control. …”

Efficacy of Hospital at Home in Patients with Heart Failure: A Systematic Review and Meta-Analysis by Amro Qaddoura (751490)

“…In RCTs, HaH demonstrated a trend to decreased readmissions (risk ratio (RR) 0.68 [0.42 to 1.09]), and had no effect on all-cause mortality (RR 0.94 [0.67 to 1.32]). …”

Restoration of miR-34 by MIF lentiviral system decreases the CD44+/CD133+ MiaPaCa2 cells and inhibits tumorspheres from the sorted CD44+/CD133+ cells. by Qing Ji (260477)

Decreased response to IL-2 in CD4⁺CD25^hi T cells correlates with an <i>IL2RA</i> risk haplotype associated with T1D and MS. by Karen Cerosaletti (501670)

Flooding and hydrologic connectivity modulate community assembly in a dynamic river-floodplain ecosystem by Stefano Larsen (115100)

“…We collected benthic chironomids and oligochaetes over a year across a lateral connectivity gradient in the semi-natural Tagliamento River (Italy). …”

DataSheet1_A Multiscale Spatiotemporal Approach for Smallholder Irrigation Detection.pdf by Terence Conlon (12415306)

“…Over withheld ground-collection survey labels, the transformer-based model achieves 96.7% accuracy over non-irrigated samples and 95.9% accuracy over irrigated samples. Over a larger set of samples independently collected via the introduced method of label supplementation, non-irrigated and irrigated labels are predicted with 98.3 and 95.5% accuracy, respectively. …”

Amoeba resistance does not predict virulence in mouse models of infection. by Thomas J. C. Sauters (17382864)

Marginal effect of date on estimated proportion of text devoted to theme. by Danielle Lamb (3411302)

Marginal effect of sex, marital status and ethnicity on estimated proportion of text devoted to theme. by Danielle Lamb (3411302)

Marginal effect of age on estimated proportion of text devoted to theme. by Danielle Lamb (3411302)

DataSheet_1_Decreased CD73+ Double-Negative T Cells and Elevated Level of Soluble CD73 Correlated With and Predicted Poor Immune Reconstitution in HIV-Infected Patients After Antir... by Xinyue Wang (286629)

“…Thus, it is a major challenge and urgently needed to distinguish PIRs early and improve their immune function in time. …”

Image_1_IL-12p40/IL-23p40 Blockade With Ustekinumab Decreases the Synovial Inflammatory Infiltrate Through Modulation of Multiple Signaling Pathways Including MAPK-ERK and Wnt.TIF by Renée H. Fiechter (10230473)

“…For some cell types this was even more pronounced at week 24, but clearly synovial inflammation was incompletely resolved. IL-17A and F, TNF, IL-6, IL-8, and IL-12p40 were not significantly downregulated in qPCR analysis of W12 total biopsies, only MMP3 and IL-23p19 were significantly decreased. …”

Table 1_(State) empathy: how context matters.docx by Katrin Heyers (20689943)

“…Taken together, this review provides a roadmap for enhancing the efficacy of future empathy studies by: (1) outlining the current theoretical and methodological considerations for disentangling trait and state empathy; (2) organizing existing empathy measurement tools to aid researchers in selecting appropriate tools for future studies; (3) describing the interplay between bottom-up processes and top-down control mechanisms for state and trait empathy; and (4) reviewing factors that increase or decrease state empathy to prevent their potential interference and enable a more accurate assessment of empathy.…”

Data Sheet 1_A novel model describing blood pressure profiles.pdf by Sabina Schlottau (21495782)

“…Exponential formulas were applied for the description of blood pressure curves (systolic and diastolic), which were used for a non-linear regression model in R.</p>Results<p>All six subjects showed a circadian pattern in systolic and diastolic blood pressure over a 14-day period. …”

Effect of alcohol and acetaldehyde on system β and System A activity in BeWo cells. by Sylvia Lui (519746)

“…<p>Na⁺-dependent ³H taurine uptake (system β activity) and Na⁺-dependent ¹⁴C-MeAIB uptake (system A activity) of BeWo cells over time. (a) system β activity and (b) system A activity, over 10, 20 and 30 minutes (Mean 23282±4809, SE = 2151, N = 6). …”

Modeling of the <i>in vitro</i> growth in <i>A.</i><i>fumigatus</i>. by Eleftheria Mavridou (365659)

“…<p>In the figure is depicted an example of model fit to a single isolate. The growth is characterized by five phases: the lag phase, where no OD-growth changes were observed; the 1st transition period, where the OD change rate increased; the log phase, where the OD change rate was maximal; and the 2nd transition period, where the OD change rate decreased to reach a stationary phase. …”

Sod2^-/- erythroid development is characterized by a maturational left shift. by Florent M. Martin (230825)

“…<p><b>A</b>. Sod2^-/- marrow (right) shows an increased fraction of immature basophilic erythroblasts (R4 gate: 1.9-fold increase) and decreased numbers of reticulocytes and mature RBC (R7 gate: 6-fold decrease), respectively, relative to Sod2^+/+ (left). …”