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46621
Automated magnetic separations of lymphocytes from human blood using a robotic platform.
Published 2011“…<p>We compared two different plate designs for the robotic platform (A,B). For each test system, Nunc vials were loaded with fresh human blood and paramagnetic beads tagged with the antibody to the whole blood cells of interest was added to the sterile vials. …”
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46622
A focal perturbation of the MET channels gives rise to an well-formed and periodic coda.
Published 2016“…B: Spectrum of the BM from E. The phase jump for a ripple is exactly half cycle. The echoes and ripples fade with the decreasing activity level of the cochlea or with the increasing longitudinal distance (about 0.75 mm) away from the focal perturbation.…”
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46623
Association between uric acid and HbA1c levels and the prevalence of DKD.
Published 2015“…Increased serum uric acid was correlated with decreased HbA1c and an elevated prevalence of DKD (<i>p</i><0.0001).…”
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46624
(a)–(d) depict the time derivation of the average investing strategies for different time-horizons.
Published 2016“…<p>In (a) with <i>ω</i> = 1 year the three major crisis in the time from 2003 until 2016 exhibit the three largest drops. …”
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46625
Monitoring the buoyant mass of single zebrafish embryos with a vibrating glass tube sensor.
Published 2017“…<p>Most zebrafish embryos that were not exposed to toxicants have unchanging buoyant masses over the first 15 hours of their development <b>(A)</b>. However, embryos exposed to known toxicants (silver nanoparticles and copper sulfate) displayed clear decreases in their buoyant masses over the same time period <b>(B-D)</b>. …”
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46626
Large-Scale Label-Free Comparative Proteomics Analysis of Polo-Like Kinase 1 Inhibition via the Small-Molecule Inhibitor BI 6727 (Volasertib) in BRAF<sup>V600E</sup> Mutant Melanom...
Published 2015“…Furthermore, we have also identified the down-regulation of multiple proteasomal subunits, resulting in a significant decrease in 20S proteasome activity. …”
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46627
Large-Scale Label-Free Comparative Proteomics Analysis of Polo-Like Kinase 1 Inhibition via the Small-Molecule Inhibitor BI 6727 (Volasertib) in BRAF<sup>V600E</sup> Mutant Melanom...
Published 2015“…Furthermore, we have also identified the down-regulation of multiple proteasomal subunits, resulting in a significant decrease in 20S proteasome activity. …”
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46628
HYPERTENSION MANAGEMENT AND PRESCRIBING PRACTICES IN PRIMARY HEALTHCARE SETTINGS IN QATAR: A MULTI-METHODS
Published 2023“…Methods: The first phase is a retrospective chart review. The second phase is a mixed-method explanatory sequential design study. …”
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46629
Global patterns and impacts of El Niño events on coral reefs: A meta-analysis
Published 2018“…Despite reports of extensive coral bleaching and up to 97% coral mortality induced by El Niño events, a quantitative synthesis of the nature, intensity, and drivers of El Niño and La Niña impacts on corals is lacking. …”
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46630
Therapeutic effect of catalase-transfected macrophages on motor functions in a PD mouse model.
Published 2013“…Number of rotations (<b>A</b>) was significantly decreased in 6-OHDA-intoxicated mice treated with catalase-transfected macrophages compared to non-treated PD mice. …”
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46631
The Multisensory Attentional Consequences of Tool Use: A Functional Magnetic Resonance Imaging Study
Published 2008“…The attentional hypothesis was supported: BOLD response in occipital cortex, particularly in the right hemisphere lingual gyrus, varied significantly as a function of tool position, increasing contralaterally, and decreasing ipsilaterally to the tool. …”
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46632
Table_2_Salivary Lactoferrin Expression in a Mouse Model of Alzheimer’s Disease.docx
Published 2021“…To test this hypothesis, we collected submandibular glands from APP/PS1 mice, as well as submandibular gland tissue from AD patients and we analysed the expression levels of key components of the salivary protein signalling pathway. A significant reduction in M3 receptor levels was found along with decreased acetylcholine (Ach) levels in submandibular glands from APP/PS1 mice. …”
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46633
A Non-Canonical Function of Zebrafish Telomerase Reverse Transcriptase Is Required for Developmental Hematopoiesis
Published 2008“…On the other hand, zTERT deficiency induced a defect in hematopoiesis through a potent and specific effect on the gene expression of key regulators in the absence of telomere dysfunction. …”
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46634
Table_1_Salivary Lactoferrin Expression in a Mouse Model of Alzheimer’s Disease.docx
Published 2021“…To test this hypothesis, we collected submandibular glands from APP/PS1 mice, as well as submandibular gland tissue from AD patients and we analysed the expression levels of key components of the salivary protein signalling pathway. A significant reduction in M3 receptor levels was found along with decreased acetylcholine (Ach) levels in submandibular glands from APP/PS1 mice. …”
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46635
The Effect of the Creatine Analogue Beta-guanidinopropionic Acid on Energy Metabolism: A Systematic Review
Published 2013“…Myocardial contractility was modestly reduced, including a decreased ventricular developed pressure, albeit with unchanged cardiac output. …”
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46636
Effect of fasudil on clinical outcomes of pulmonary hypertension: a systematic review and meta-analysis
Published 2024“…<p>Pulmonary hypertension (PH) is a life-threatening condition with high mortality, categorized into Group 1-5 by distinct etiologies. …”
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46637
Optimization of a glucagon-like peptide 1 receptor antagonist antibody for treatment of hyperinsulinism
Published 2023“…TB-222-023 effectively decreased insulin secretion in primary isolated pancreatic islets from a mouse model of hyperinsulinism, <em>Sur1</em>-/- mice, and in islets from an infant with HI as well as increased plasma glucose and decreased the insulin to glucose ratio in <em>Sur1</em>-/- mice. …”
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46638
Release of Membrane-Bound Vesicles and Inhibition of Tumor Cell Adhesion by the Peptide Neopetrosiamide A
Published 2010“…</p><h3>Methodology/Principal Findings</h3><p>We show that NeoA reversibly inhibits tumor cell adhesion, disassembles focal adhesions in pre-attached cells, and decreases the level of β1 integrin subunits on the cell surface. …”
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46639
Trophozoites of <i>Gregarina cuneata</i> observed using a transmission electron microscope.
Published 2013“…</b> Trophozoite exhibiting a quite completely decreased epimerite (asterisks) with numerous mitochondria and gradual detachment (arrowhead) from host cell (hc), membrane fusion sites (in circles), protomerite (p).…”
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46640
Acute morphine causes a dose-dependent MOR – G protein coupling switch.
Published 2013“…<p>Densitometric quantitation (<i>B</i>) of blots (<i>A</i>) shows that the level of MOR–Gs coupling after 15-min morphine exposure increases progressively as dose increases from 0.1 to 100 µM concentrations. …”