miR-4437 and miR-4674 decrease γ-synuclein expression in SKBR3 with moderate endogenous level of γ-synuclein expression, but do not affect the level of its expression in cells over... by Irina Surgucheva (95526)

Both the HRM and the HTM reproduce the key features of medfly mortality pattern: (i) increase, (ii) local maximum, (iii) U-shape, (iv) second local maximum, higher than the first o... by Yann Le Cunff (102173)

Δ<i>atpG</i> exhibits reduced intracellular pH compared to WT both in the presence/absence of NO·. by Melinda R. Grosser (4976720)

“…<p><b>A.</b><i>S</i>. <i>aureus</i> WT, Δ<i>atpG</i> and Δ<i>atpG</i> + pATPase were grown in TSB 5g/L glucose and were exposed to NO· mix (10mM NOC12, 1mM DEANO) at OD₆₅₀ 0.25 (t0). …”

DNA recognition by an RNA-guided bacterial Argonaute by Kevin W. Doxzen (4031057)

“…<div><p>Argonaute (Ago) proteins are widespread in prokaryotes and eukaryotes and share a four-domain architecture capable of RNA- or DNA-guided nucleic acid recognition. …”

Expression of candidate genes in human neutrophils upon <i>S</i>. <i>aureus</i> infection. by Qin Yan (281622)

“…acc=GSE16837" target="_blank">http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE16837</a>) was analyzed. <i>Cd97</i> (0.44 fold, p<0.0001) and <i>Lyl1</i> (0.48 fold, p<0.05) were decreased at 6hr after <i>S</i>. …”

S2 File - by Jinfeng Zhao (142391)

“…The roles of Klotho were further confirmed through knockdown of Klotho by small interfering RNA (siRNA) in C57BL/6J mice.Q-PCR and Western blot were performed to quantify determine the expression of relevant genes and proteins in the kidney. Results: Aging decreased Klotho expression via activated the upstream TGF-β1/p53/miR34a signaling pathway and affected its downstream signaling pathways, ultimately leading to renal fibrosis. …”

Classical Galactosemia: Insight into Molecular Pathomechanisms by Differential Membrane Proteomics of Fibroblasts under Galactose Stress by Simon Staubach (2118262)

“…The membrane-anchored N-glycoprotein receptor CD109 was concertedly decreased under galactose-stress together with cadherin-13, GLIPR1, glypican-1, and semaphorin-7A. …”

Table_1_Secondary Outcomes of Implemented Depression Prevention in Adolescents: A Randomized Controlled Trial.DOCX by Karlijn W. J. de Jonge-Heesen (10181135)

“…Latent growth curve analyses revealed that there was a significant decrease in anxiety in both conditions and that this decrease was significantly larger in the intervention condition than in the control condition. …”

Image_1_Secondary Outcomes of Implemented Depression Prevention in Adolescents: A Randomized Controlled Trial.PNG by Karlijn W. J. de Jonge-Heesen (10181135)

“…Latent growth curve analyses revealed that there was a significant decrease in anxiety in both conditions and that this decrease was significantly larger in the intervention condition than in the control condition. …”

Triple immunofluorescence labeling comparing both sarcomeric actin and VDAC expression in control versus MFN2 mutant mice. by Peter Bannerman (3373028)

“…Initially, note the selective expression of the mutant form of MFN2 in satellite cells of the mutant myofibers with occasion dissemination into the muscle fiber (white arrow-heads). Also note both the decreased intensity of sarcomeric actin immunolabelling in the mutant mice versus wild-type mice (compare A and B) and the relative disruption of striated myofibrillar distribution of VDAC positive mitochondria in mutant micrograph D versus C. …”

Model for the restoration of Q₆ biosynthesis in three revertants. by Agape M. Awad (8917736)

“…<p><i>A</i>, Under conditions of Coq8 expression in wild-type yeast, benchmark values of Q₆ production are noted and the wild-type amounts of key Coq polypeptides (Coq4, Coq7, Coq8, and Coq9) are defined. …”

<i>C</i>. <i>burnetii</i> reduces lysosomes independent of autophagy. by Dhritiman Samanta (8174058)

“…(B) Immunoblot revealed that ATG5 protein was depleted by siATG5, resulting in decreased autophagy as demonstrated by a loss of LC3-II. …”

Effects of neutralizing anti-CCL3 antibody on the number of macrophages at the damaged site and the decrease in area of bone defect on day 4 in <i>uPA</i>^+/+ and uPA<sup... by Naoyuki Kawao (181472)

Change of potential ecosystem services (decrease (↘) and increase (↗) greater than 10%) between practices in each category of grassland, for the drastic and local scenario (column... by Pénélope Lamarque (637046)

“…<p>Change of potential ecosystem services (decrease (↘) and increase (↗) greater than 10%) between practices in each category of grassland, for the drastic and local scenario (column “D”) and the intermittent and international scenario (column “I”) (data from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0107572#pone.0107572-Lamarque4" target="_blank">[61]</a>).…”

Simulated and observed PD effect-time profiles for indomethacin presented as % decrease in PGEM (13, 14-dihydro-15-ketoprostaglandin E2) plasma concentration vs. time after single... by Saeed Alqahtani (802779)

VgrS senses Fe³⁺ depletion by its sensor region. by Li Wang (15202)

“…<p>(A) Fe³⁺ inhibits the autophosphorylation of full-length VgrS. …”

Data_Sheet_1_GnRH-mediated suppression of S100A4 expression inhibits endometrial epithelial cell proliferation in sheep via GNAI2/MAPK signaling.PDF by Xiyao Jiao (18695935)

“…</p>Methods<p>Transcriptome sequencing was used to determine the regulatory effect of GnRH on the ewe endometrium, and the S100A4 gene, which showed altered transcription, was screened as a candidate regulator of this effect. …”

Data_Sheet_1_GnRH-mediated suppression of S100A4 expression inhibits endometrial epithelial cell proliferation in sheep via GNAI2/MAPK signaling.PDF by Xiyao Jiao (18695935)

“…</p>Methods<p>Transcriptome sequencing was used to determine the regulatory effect of GnRH on the ewe endometrium, and the S100A4 gene, which showed altered transcription, was screened as a candidate regulator of this effect. …”

Impact of CD4+ T Cell Responses on Clinical Outcome following Oral Administration of Wild-Type Enterotoxigenic <i>Escherichia coli</i> in Humans by Monica A. McArthur (160077)

“…We furthermore demonstrated that increased expression of the gut-homing molecule integrin α4β7 by peripheral T follicular helper cells (pT_fh) correlated with decreased stool volume and increased ETEC-specific IgA B memory cell (B_M) development. …”

Omeprazole (Ome) does not increase IL-4-stimulated eotaxin-3 mRNA degradation, and does not decrease STAT6 phosphorylation or nulcear translocation in EoE1-T and EoE2-T cell lines. by Xi Zhang (83736)