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48781
Image_4_Genetic Adaptation of a Mevalonate Pathway Deficient Mutant in Staphylococcus aureus.PDF
Published 2018“…<p>In this study we addressed the question how a mevalonate (MVA)-auxotrophic Staphylococcus aureusΔmvaS mutant can revert to prototrophy. …”
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48782
A competing risk survival analysis of the sociodemographic factors of COVID-19 in-hospital mortality in Ecuador
Published 2023“…Being of advanced age, especially older than or equal to 75 years (SHR = 17.97; 95%CI: 13.08-24.69), being a man (SHR = 1.29; 95%CI: 1.22-1.36), living in rural areas (SHR = 1.18; 95%CI: 1.10-1.26), and receiving care in a public health center (SHR = 1.64; 95%CI: 1.51-1.78) were factors that increased the incidence of death from COVID-19, while living at an elevation higher than 2,500 meters above sea level (SHR = 0.69; 95%CI: 0.66-0.73) decreased this incidence. …”
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48783
Table_1_Effect of Limonene on Cancer Development in Rodent Models: A Systematic Review.DOCX
Published 2021“…<p>Cancer is a major health issue and one of the leading causes of death worldwide. …”
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48784
Rescue of Sox10 expression can occur in absence of a rescue of Six1 expression.
Published 2023“…<p>(a–f) In situ hybridization for Sox10 (a–c) and Six1 (d–f), in embryos injected with CMO (a, <i>n</i> = 29; d, <i>n</i> = 56), MMP28-MOspl (b, <i>n</i> = 40; e, <i>n</i> = 43), or co-injected with MMP28-MOspl and mRNA for MMP28wt-GFP (c, <i>n</i> = 31; f, <i>n</i> = 41). …”
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48785
Table_2_The Potential of Physical Exercise to Mitigate Radiation Damage—A Systematic Review.xlsx
Published 2021“…<p>There is a need to investigate new countermeasures against the detrimental effects of ionizing radiation as deep space exploration missions are on the horizon.…”
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48786
Early detection of pancreatic cancer in mouse models using a novel antibody, TAB004
Published 2018“…<div><p>Pancreatic ductal adenocarcinoma (PDA) is the fourth-leading cause of cancer death in the United States with a 5-year overall survival rate of 8% for all stages combined. …”
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48787
Blimp1 is a target of KLF4 that binds to KLF4 and activates viral transcription.
Published 2016“…<p>(5A) Protein lysates from KLF4-depleted HFKs and HFK-31gen cells were analyzed for Blimp1 levels. …”
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48788
Video1_Design of a Flexible Wasp-Inspired Tissue Transport Mechanism.MP4
Published 2021“…The transport rate can be increased by increasing the rotational velocity of the cam. A rotational velocity of 25 RPM resulted in a transport rate of 0.8 mm/s and increasing the rotation velocity of the cam to 80 RPM increased the transport rate to 2.3 mm/s though the stroke efficiency decreased by increasing the rotational velocity of the cam. …”
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48789
Table_1_Genetic Adaptation of a Mevalonate Pathway Deficient Mutant in Staphylococcus aureus.DOCX
Published 2018“…<p>In this study we addressed the question how a mevalonate (MVA)-auxotrophic Staphylococcus aureusΔmvaS mutant can revert to prototrophy. …”
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48790
Presentation_1_MPV17 Mutations Are Associated With a Quiescent Energetic Metabolic Profile.PPTX
Published 2021“…The MPV17 gene encodes an inner membrane mitochondrial protein that was recently described to function as a non-selective channel. Although its exact function is unknown, it is thought to be important in the maintenance of mitochondrial membrane potential (ΔΨm). …”
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48791
Ferroptosis Induction by a New Pyrrole Derivative in Triple Negative Breast Cancer and Colorectal Cancer
Published 2025“…Given its high activity, compound <b>12</b> represents a promising therapeutic candidate for TNBC and CRC.…”
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48792
Ferroptosis Induction by a New Pyrrole Derivative in Triple Negative Breast Cancer and Colorectal Cancer
Published 2025“…Given its high activity, compound <b>12</b> represents a promising therapeutic candidate for TNBC and CRC.…”
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48793
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48794
Time course of central retinal thickness (CRT) in all eyes.
Published 2025“…The mean number of treatments—including anti-VEGF, STTA, MA-PC, and PPV—in the year before surgery was 2.6 ± 1.6, 0.3 ± 0.8, 0.6 ± 0.8, and 0.1 ± 0.3, respectively, with a total of 3.7 ± 1.7 treatments. These treatment frequencies declined significantly after surgery: at 1 year postoperatively, the averages were 0.8 ± 1.9, 0.0 ± 0.2, 0.3 ± 1.0, 0.0, and 1.2 ± 2.2; at 2 years, 0.7 ± 2.0, 0.1 ± 0.6, 0.0 ± 0.2, 0.0 ± 0.2, and 1.0 ± 2.1; and at 3 years, 0.9 ± 2.2, 0.0, 0.2 ± 1.0, 0.0 ± 0.2, and 1.1 ± 3.1 (Kruskal-Wallis test, p < 0.001; <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0332941#pone.0332941.g003" target="_blank">Fig 3</a>). …”
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48795
Image_2_A Two-Gene-Based Diagnostic Signature for Ruptured Intracranial Aneurysms.TIF
Published 2021“…The RT-qPCR further validated that compared with the healthy samples, the expression levels of IL2RB and CCR7 were decreased in ruptured IA samples.</p><p>Conclusions: This study might be helpful for cohorts who have a high risk of ruptured IA for early diagnosis and prevention of the disease.…”
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48796
Image_3_The Association Between COVID-19 and Thyroxine Levels: A Meta-Analysis.jpeg
Published 2022“…Objectives<p>Recently, a number of reports have described the potential relationship between COVID-19 and thyroid hormones, but the results were conflicting. …”
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48797
Consequences of Exchanging Carbohydrates for Proteins in the Cholesterol Metabolism of Mice Fed a High-fat Diet
Published 2012“…We examined the impact of high-protein and high-fat diets on cholesterol metabolism by comparing the plasma cholesterol and the expression of cholesterol biosynthesis genes in the liver of mice fed a high-fat (HF) diet that has a high (H) or a low (L) protein-to-carbohydrate (P/C) ratio. …”
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48798
Table_3_A Two-Gene-Based Diagnostic Signature for Ruptured Intracranial Aneurysms.DOCX
Published 2021“…The RT-qPCR further validated that compared with the healthy samples, the expression levels of IL2RB and CCR7 were decreased in ruptured IA samples.</p><p>Conclusions: This study might be helpful for cohorts who have a high risk of ruptured IA for early diagnosis and prevention of the disease.…”
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48799
Table_2_Evaluation of Wearable Technology in Dementia: A Systematic Review and Meta-Analysis.DOC
Published 2021“…Observational studies providing physiological data measured by wearable technology on participants with dementia with a mean age ≥50. Data were extracted according to PRISMA guidelines and methodological quality assessed independently using Downs and Black criteria. …”
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48800
Adding Biotic Interactions into Paleodistribution Models: A Host-Cleptoparasite Complex of Neotropical Orchid Bees
Published 2015“…Additionally, since <i>A</i>. <i>caerulea</i> is more frequently found in the Amazon rather than the Cerrado areas, a secondary objective was to evaluate whether this species is increasing or decreasing its distribution given South American past and current climatic conditions. …”