Effects of establishing a trauma center on the mortality rate among injured pediatric patients in Japan by Takashi Muguruma (4691542)

“…The aim of this study was to evaluate children’s mortality before and after the establishment a trauma center by using standard mortality ratios (SMR) and a modified observed-expected chart.…”

Total cholesterol variability and risk of atrial fibrillation: A nationwide population-based cohort study by Eun Roh (1526662)

“…Kaplan–Meier analysis demonstrated a decreased disease-free probability in the highest quartile group of TC variability compared to that in the other groups. …”

Image_2_Cyclophosphamide augments the efficacy of in situ vaccination in a mouse melanoma model.tif by Noah Tsarovsky (15174500)

“…We hypothesized that cyclophosphamide (CY), a chemotherapeutic agent capable of depleting T regulatory cells (Tregs), would augment in situ vaccination. …”

Data_Sheet_6_Microbial Community Response to a Novel Salmon Resource Subsidy.PDF by Courtney E. Larson (8278182)

“…<p>Salmon decomposition is traditionally viewed through the lens of energy and nutrient subsidies, but not as a potential “microbial subsidy.” Microbial communities residing on and within spawning salmon are directly introduced into streams after host death. …”

Image_3_A shift of brain network hub after spinal cord injury.tif by Kohei Matsubayashi (17178100)

“…We evaluated “centrality,” a representative parameter of network analysis. …”

pH plays a role in the mode of action of trimethoprim on <i>Escherichia coli</i> by Haitham AlRabiah (5513648)

“…These results provide a wider view of the action of trimethoprim. Metabolomics indicated alternative metabolism areas to be investigated to further understand the off-target effects of trimethoprim.…”

Table_1_TNAP—a potential cytokine in the cerebral inflammation in spastic cerebral palsy.xlsx by Xiao-Kun Wang (5745635)

“…In contrast, compared with the sham rats, the model rats demonstrated a significant increase in osteopontin and proinflammatory biomarkers in both the plasma and cerebral cortex on the ischemic side whereas serum 25 hydroxyvitamin D and IL-10 were significantly decreased. …”

Selection purged mutations in most of <i>env</i>, but favored mutations at a few sites. by Hugh K. Haddox (3396929)

“…For all other sites, the frequency of nonsynonymous mutations decreased substantially after selection. <b>(B)</b> The sites at which the error-corrected mutation frequency increased >3-fold are similar between replicates, indicating consistent selection for tissue-culture adaptation at a few positions. …”

Data_Sheet_2_Genetic Susceptibility to Gestational Diabetes Mellitus in a Chinese Population.docx by Minkai Cao (8495376)

“…</p><p>Results: We observed that FTO rs1121980 and KCNQ1 rs163182 conferred a decreased GDM risk in the dominant and additive model [additive model: OR (95% CI) = 0.79 (0.67–0.94), P = 0.007 for rs1121980; OR(95%CI) = 0.84 (0.73–0.96), P = 0.009 for rs163182], whereas MC4R rs12970134 and PROX1 rs340841 conferred an increased GDM risk in the dominant, recessive, and additive model [additive model: OR(95%CI) = 1.25 (1.07–1.46), P = 0.006 for rs12970134; OR(95%CI) = 1.22 (1.07–1.39), P = 0.002 for rs340841). …”

A novel method of inducing endogenous pupil oscillations to detect patients with unilateral optic neuritis by Cedric Lamirel (5675438)

“…With this biofeedback setting, an increasing pupil size transforms into a high luminance, entraining a pupil constriction that in turn decreases the stimulus luminance, and so on, resulting in endogenously generated POs. …”

Neonatal sepsis in Iran: A systematic review and meta-analysis on national prevalence and causative pathogens by Zahra Akbarian-Rad (8356659)

“…Prevalence rate in boys (20.42%; 95%CI, 9.03–34.8%) was slightly higher than girls (18.5%; 95%CI, 7.4–32.8). A decreasing trend in prevalence of neonatal sepsis was found in recent years, although not statistically significant (c = -0.005; <i>P</i> value = 0.4). …”

Subthalamic Nucleus Stimulation Affects Theory of Mind Network: A PET Study in Parkinson's Disease by Julie Péron (251008)

“…</p><h3>Conclusion/Significance</h3><p>These results seem to confirm that STN DBS hinders the ability to infer the mental states of others and modulates a distributed network known to subtend ToM.</p></div>…”

EGFRvIII expression triggers a metabolic dependency and therapeutic vulnerability sensitive to autophagy inhibition by Barry Jutten (4804575)

“…Our findings disclose the unique autophagy dependency of EGFRvIII⁺ glioblastoma as a therapeutic opportunity. Chloroquine treatment may therefore be considered as an additional treatment strategy for glioblastoma patients and can reverse the worse prognosis of patients with EGFRvIII⁺ glioblastoma.…”

Table_4_Causal association of circulating cytokines with sepsis: a Mendelian randomization study.xlsx by Shan Lin (228596)

“…</p>Methods<p>We performed a two-sample MR analysis to investigate this causality relationship in individuals of European ancestry. …”

Data_Sheet_5_Microbial Community Response to a Novel Salmon Resource Subsidy.pdf by Courtney E. Larson (8278182)

“…<p>Salmon decomposition is traditionally viewed through the lens of energy and nutrient subsidies, but not as a potential “microbial subsidy.” Microbial communities residing on and within spawning salmon are directly introduced into streams after host death. …”

Supplementary Material for: Effects of Dendritic Cell Subset Manipulation on Airway Allergy in a Mouse Model by Murakami R. (3223968)

“…The levels of serum OVA-specific IgG1, IgG2a, and IgE were also determined by ELISA. <b><i>Results:</i></b> The allergic symptom scores were significantly decreased in 33D1+ DC-depleted or DEC-205+ DC-activated AR mice. …”

Diagnosis of Morquio Syndrome in Dried Blood Spots Based on a New MRM-MS Assay by Claudia Cozma (766350)

“…<div><p>Background</p><p>Mucopolysaccharidosis IVA (MPS IVA; Morquio A disease) is an autosomal recessive disease caused and characterized by a decreased activity of N-acetylgalactosamine-6-sulfate sulfatase (GALNS), resulting in accumulation of keratan sulfate and chondroitin-6-sulfate in tissues and secondary organ damage. …”

Spatial Modelling of Soil-Transmitted Helminth Infections in Kenya: A Disease Control Planning Tool by Rachel L. Pullan (231093)

“…Comparison of the predicted distributions for 1989 and 2009 show how observed STH prevalence has gradually decreased over time. The model estimated that a total of 2.8 million school-age children live in districts which warrant mass treatment.…”

Magnesium oxide use and reduced risk of dementia: a retrospective, nationwide cohort study in Taiwan by Nian-Sheng Tzeng (427571)

“…</p> <p><b>Conclusions:</b> The patients who used MgO had a decreased risk of developing dementia. Further studies on the effects of MgO in reducing the risk of dementia are therefore warranted.…”

Table_1_The effect of an anti-inflammatory diet on chronic pain: a pilot study.DOCX by Marta Sala-Climent (16538433)

“…A food consumption score (with a maximum of 156 points) was then applied to evaluate patient adhesion to the proposed diet. …”