Supplementary file 1_Metabolic insights into hypoxia adaptation in adolescent athletes at different altitudes: a cross-sectional study.docx by Carlos A. R. Sánchez (21288050)

Data_Sheet_1_The Epidemiology of Ground Glass Opacity Lung Adenocarcinoma: A Network-Based Cumulative Meta-Analysis.docx by Xiongfei Li (9147545)

“…</p><p>Methods: We retrieved all solitary GGO adenocarcinoma lung cancer (ADLC) on the PubMed, Cochrane Library, and Embase databases until January 1, 2019 and extracted the general information to perform the meta-analysis, mainly focusing on age, gender, and smoking status.</p><p>Results: A total of 8,793 solitary GGO ADLC patients from 53 studies were included in this analysis. …”

Table_1_Percutaneous stent implantation for occluded central shunts in adults: A case report and review of current evidence.DOCX by Yaser Jenab (14146713)

“…We also reported the case of a 33-year-old man with cyanotic CHD and a occluded central aorto-pulmonary shunt, who was successfully treated with percutaneous balloon dilatation and subsequently stent implantation at our institution.…”

Repeated elicitations of <i>N. attenuata</i> leaves at the scale of a feeding, early-instar <i>M. sexta</i>. by William Stork (374001)

“…Conjugation requires both <i>Na</i>TD and <i>Na</i>JAR4; silencing <i>Na</i>JAR4 and <i>Na</i>TD transcript accumulation decreases TPI activity <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004697#pone.0004697-Wang1" target="_blank">[25]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004697#pone.0004697-Kang1" target="_blank">[30]</a>. …”

Data_Sheet_1_Multiplex T Cell Stimulation Assay Utilizing a T Cell Activation Reporter-Based Detection System.zip by Sarah E. Mann (8692515)

“…This allows for the combination of multiple T-hybridoma lines within a single reaction. Sensitivity to stimulation is not decreased by adding fluorescent proteins or multiplexing T cells. …”

Table_1_A Cost-Effectiveness and Quality of Life Analysis of Different Approaches to the Management and Treatment of Localized Prostate Cancer.DOCX by Aleksandra Harat (813785)

“…Microsimulations of radical prostatectomy, 3D-conformal radiotherapy, or active monitoring were performed using Medicare reimbursement schedules and clinical trial results for a target population of men aged 50–69 years with newly diagnosed localized prostate cancer (T1-T2, NX, M0) over a time horizon of 10 years. …”

Impact of Cu(II) Binding on Structures and Dynamics of Aβ₄₂ Monomer and Dimer: Molecular Dynamics Study by Pham Dinh Quoc Huy (2944638)

“…The simulation of dimers was conducted with the Cu­(II)/Aβ stoichiometric ratios of 1:1 and 1:2. For the 1:1 ratio Cu­(II) delays the Aβ dimerization process as observed in a number of experiments. …”

Data_Sheet_1_Assessing the association between age at first sexual intercourse and migraine: a Mendelian randomization study.docx by Guoliang Zhu (4726623)

“…Stratified analyses provided suggestive evidence of the causal relationship between delayed AFS and a decreased risk of migraine for both males (OR = 0.71, 95% CI [0.59 to 0.84]) and females (OR = 0.73, 95% CI [0.61 to 0.89]). …”

Data_Sheet_1_Impact of a combination sound therapy on tinnitus distress: an exploratory one-year longitudinal study.docx by Dina Lelic (11051240)

“…The degrees of improvement in THI, TFI and tinnitus annoyance were correlated with daily hours of sound-therapy use but not with daily hours of amplification-only or total device use.</p>Conclusions<p>A combination sound therapy consisting of therapy sounds, amplification as needed, and counseling was associated with a reduction in tinnitus-related distress. …”

Video_4_Distinct Mitochondrial Remodeling During Mesoderm Differentiation in a Human-Based Stem Cell Model.MP4 by Sepideh Mostafavi (11561719)

“…Remodeling of mitochondria and metabolism, with the shift from glycolysis to oxidative phosphorylation (OXPHOS), plays a fundamental role in maintaining pluripotency and stem cell fate. …”

DataSheet1_A framework for computer-aided high performance titanium alloy design based on machine learning.pdf by Suyang An (18371967)

“…However, traditional material design methods encounter numerous calculations and experimental trial-and-error processes, leading to increased costs and decreased efficiency in material design. The data-driven model presents an intriguing alternative to traditional material design methods by offering a novel approach to expedite the materials design process. …”

PPA1 Regulates Systemic Insulin Sensitivity by Maintaining Adipocyte Mitochondria Function as a Novel PPARγ Target Gene by Ye Yin (420350)

“…<a>Downregulation of mitochondrial function in adipose tissue is considered as one important driver for the development of obesity-associated metabolic disorders. …”

Table_3_ΔFosB is part of a homeostatic mechanism that protects the epileptic brain from further deterioration.DOCX by Jerome Clasadonte (17777424)

“…Furthermore, prolonged inhibition of ΔFosB using a ΔJunD construct to block ΔFosB signaling in a mouse model of Alzheimer’s disease, that exhibits spontaneous recurrent seizures, led to similar findings, with increased neuroinflammation and decreased NPY expression in mossy fibers. …”

Table4_Global Burden of Inflammatory Bowel Disease Among Children and Adolescents: A Comprehensive Analysis (1990–2019).XLSX by Xuejie Chen (1408159)

“…During the same period, the DALY numbers decreased by 53.5%, from 243,081.06 to 113,119.86, with all SDI regions experiencing a clear drop in DALYs except high SDI regions. …”

Interferon alpha-inducible protein 27 (IFI27) is a prognostic marker for pancreatic cancer based on comprehensive bioinformatics analysis by Shu Huang (1817500)

“…Analysis of infiltrating immune cells displayed that higher expression of IFI27 expression correlates with decreased CD8 + T cells and increased M2 macrophages in the tumor immune microenvironment (TIME), then biochemical analyses of a mouse model and immunohistochemical (IHC) staining verified that glycolytic enzymes and M2 macrophages increased significantly in pancreatic cancer tissues. …”

DataSheet_1_Increased Adaptive Variation Despite Reduced Overall Genetic Diversity in a Rapidly Adapting Invader.docx by Daniel Selechnik (6930500)

“…Nonetheless, toads encounter novel environmental challenges in Australia, and the transition between genetic clusters occurs at a point along the invasion transect where temperature rises and rainfall decreases. …”

Functional Assays and Metagenomic Analyses Reveals Differences between the Microbial Communities Inhabiting the Soil Horizons of a Norway Spruce Plantation by Stéphane Uroz (281637)

“…In this context, the long-term differentiation of the forest soils into horizons may impact the assembly and the functions of the soil microbial communities. To gain a more comprehensive understanding of the ecology and functional potentials of these microbial communities, a suite of analyses including comparative metagenomics was applied on independent soil samples from a spruce plantation (Breuil-Chenue, France). …”

A DNA repair protein and histone methyltransferase interact to promote genome stability in the <i>Caenorhabditis elegans</i> germ line by Bing Yang (142278)

“…<div><p>Histone modifications regulate gene expression and chromosomal events, yet how histone-modifying enzymes are targeted is poorly understood. Here we report that a conserved DNA repair protein, SMRC-1, associates with MET-2, the <i>C</i>. …”

Se-Methylselenocysteine (SMC) Improves Cognitive Deficits by Attenuating Synaptic and Metabolic Abnormalities in Alzheimer’s Mice Model: A Proteomic Study by Xiubo Du (1734001)

“…Se-methylselenocysteine (SMC) is a major selenocompound in selenium (Se) enriched plants and has been found to ameliorate neuropathology and cognitive deficits in triple-transgenic mice model of Alzheimer’s disease (3 × Tg-AD mice). …”

Individual to Community-Level Faunal Responses to Environmental Change from a Marine Fossil Record of Early Miocene Global Warming by Christina L. Belanger (168178)

“…This record of benthic foraminiferal and molluscan community change from continental shelf depths spans a past interval environmental change (∼20.3-16.7 mya) during which the region warmed 2.1–4.5°C, surface productivity and benthic organic carbon flux increased, and benthic oxygenation decreased, perhaps driven by intensified upwelling as on the modern Oregon coast. …”