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62081
Image_1_Metformin Mitigates Cartilage Degradation by Activating AMPK/SIRT1-Mediated Autophagy in a Mouse Osteoarthritis Model.jpeg
Published 2020“…In cultured primary murine chondrocytes, IL-1β aggravated apoptosis and catabolic response in a dose-dependent manner. In the presence of IL-1β, metformin increased phosphorylated levels of AMPKα and upregulated SIRT1 protein expression, leading to an increase in autophagy as well as a decrease in catabolism and apoptosis. …”
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62082
Data_Sheet_2_Predictors of Permanent Pacemaker Implantation in Patients After Transcatheter Aortic Valve Replacement in a Chinese Population.DOCX
Published 2022“…Few studies have evaluated the requirement for PPM implantation due to ECG changes following TAVR in a Chinese population.</p><p>Objective: Our study aimed to evaluate the incidence and predictors of PPM implantation in a cohort of Chinese patients with TAVR.…”
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62083
Data_Sheet_1_Stabilization of a Cart Inverted Pendulum: Improving the Intermittent Feedback Strategy to Match the Limits of Human Performance.pdf
Published 2019“…The difficulty of the task grows exponentially with the decrease of the length of the stick and a stick length of 32 cm is considered as a human limit even for well-trained subjects. …”
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62084
Image 4_Risk factors for thoracic aortic aneurysm and dissection among diabetic patients: a nationwide population-based study.tif
Published 2025“…Meanwhile, the risk of TAAD was decreased in patients with a longer diabetes duration (HR: 0.97, 95% CI: 0.96–0.99) and metformin use (HR: 0.91 95% CI: 0.85–0.97).…”
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62085
Cyclosporin A Associated Helicase-Like Protein Facilitates the Association of Hepatitis C Virus RNA Polymerase with Its Cellular Cyclophilin B
Published 2011“…The downregulation of CAHL in the cells resulted in a decrease of HCV genome replication. CAHL formed a complex with HCV-derived RNA polymerase NS5B and host-derived cyclophilin B (CyPB), known as a cellular cofactor for HCV replication, to regulate NS5B-CyPB interaction.…”
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62086
Sacrifice Template Strategy to the Fabrication of a Self-Cleaning Nanofibrous Membrane for Efficient Crude Oil-in-Water Emulsion Separation with High Flux
Published 2020“…However, most materials are extremely susceptible to pollution during oil–water separation, which drastically restricts their widespread applications. Herein, a momordica-charantia-like nanofibrous membrane (MCNM) with underwater superoleophobic performance was fabricated through a sacrifice template strategy by the electrospinning solution of zeolitic imidazolate framework-8 (ZIF-8) and polyacrylonitrile particles. …”
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62087
Table 2_Efficacy of dietary polyphenol supplement in patients with non-alcoholic fatty liver disease: a network meta-analysis.docx
Published 2025“…Background<p>Non-alcoholic fatty liver disease (NAFLD) has become a public health issue worldwide. Dietary polyphenols are naturally occurring plant active ingredients and are widely employed in the treatment of NAFLD. …”
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62088
Prevention of Tungiasis and Tungiasis-Associated Morbidity Using the Plant-Based Repellent Zanzarin: A Randomized, Controlled Field Study in Rural Madagascar
Published 2013“…In the shoe group, only a marginal decrease in the intensity of infestation and in the attack rate was observed. …”
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62089
Table 1_Regional high iron deposition is linked with cognitive impairments in peritoneal dialysis: a quantitative susceptibility mapping study.doc
Published 2025“…Every 100 μg/L increase in SF beyond this threshold was associated with a 3.1-point decrease in MoCA score. Iron deposition in the left amygdala showed significant correlations with scores on the Digit Symbol Test (DST), Self-Rating Depression Scale (SDS), Self-Rating Anxiety Scale (SAS), and Verbal Fluency Test (VFT), but exhibited no direct association with peripheral iron metabolism parameters.…”
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62090
Table 1_Efficacy of dietary polyphenol supplement in patients with non-alcoholic fatty liver disease: a network meta-analysis.docx
Published 2025“…Background<p>Non-alcoholic fatty liver disease (NAFLD) has become a public health issue worldwide. Dietary polyphenols are naturally occurring plant active ingredients and are widely employed in the treatment of NAFLD. …”
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62091
Table_2_Nutrient Scarcity in a New Defined Medium Reveals Metabolic Resistance to Antibiotics in the Fish Pathogen Piscirickettsia salmonis.pdf
Published 2021“…The mechanism for antibiotic resistance to ampicillin in the defined medium was further explored and was proven to be associated to a decrease in the bacterial central metabolism, including the TCA cycle, the pentose-phosphate pathway, energy production, and nucleotide metabolism, and it was not associated with decreased growth rate of the bacterium or with the expression of any predicted ARG. …”
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62092
Table_1_Nutrient Scarcity in a New Defined Medium Reveals Metabolic Resistance to Antibiotics in the Fish Pathogen Piscirickettsia salmonis.xlsx
Published 2021“…The mechanism for antibiotic resistance to ampicillin in the defined medium was further explored and was proven to be associated to a decrease in the bacterial central metabolism, including the TCA cycle, the pentose-phosphate pathway, energy production, and nucleotide metabolism, and it was not associated with decreased growth rate of the bacterium or with the expression of any predicted ARG. …”
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62093
Table_3_Balance Adaptation While Standing on a Compliant Base Depends on the Current Sensory Condition in Healthy Young Adults.DOCX
Published 2022“…</p>Conclusion<p>Balance adaptation occurs during standing on foam. Adaptation leads to a progressive increase in the amplitude of the lowest frequencies of the spectrum and a concurrent decrease in the high-frequency range. …”
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62094
Image_1_Nutrient Scarcity in a New Defined Medium Reveals Metabolic Resistance to Antibiotics in the Fish Pathogen Piscirickettsia salmonis.TIF
Published 2021“…The mechanism for antibiotic resistance to ampicillin in the defined medium was further explored and was proven to be associated to a decrease in the bacterial central metabolism, including the TCA cycle, the pentose-phosphate pathway, energy production, and nucleotide metabolism, and it was not associated with decreased growth rate of the bacterium or with the expression of any predicted ARG. …”
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62095
Table_1_A meta-analysis to examine whether nitrification inhibitors work through selectively inhibiting ammonia-oxidizing bacteria.docx
Published 2022“…Decrease in N<sub>2</sub>O emissions with NI addition was significantly correlated with AOB changes (R<sup>2</sup> = 0.135, n = 110, P < 0.01) rather than changes in AOA, and there was an obvious correlation between the changes in NH4+ concentration and AOB amoA gene abundance after NI application (R<sup>2</sup> = 0.037, n = 136, P = 0.014). …”
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62096
Rates of False-Negative Screening in Prostate Specific Antigen Secondary to 5-Alpha Reductase Inhibitor Usage: A Quality-Improvement Initiative
Published 2022“…We investigated false-screening rates in men on 5-ARIs undergoing PSA testing and whether ordering physicians noticed false negative findings. Materials and Methods A single institution, retrospective study was conducted on patients with a PSA value documented between 2014 and 2017. …”
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62097
Table_1_Blocking Opioid Receptors in a Songbird Cortical Region Modulates the Acoustic Features and Levels of Female-Directed Singing.docx
Published 2020“…The AFP in songbirds includes the cortical/pallial region LMAN (lateral magnocellular nucleus of the anterior nidopallium) which projects to Area X, a nucleus of the avian basal ganglia. In the present study, microdialysis was used to infuse different doses of the opioid antagonist naloxone in LMAN of adult male zebra finches. …”
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62098
Table_1_A meta-analysis to examine whether nitrification inhibitors work through selectively inhibiting ammonia-oxidizing bacteria.xlsx
Published 2022“…Decrease in N<sub>2</sub>O emissions with NI addition was significantly correlated with AOB changes (R<sup>2</sup> = 0.135, n = 110, P < 0.01) rather than changes in AOA, and there was an obvious correlation between the changes in NH4+ concentration and AOB amoA gene abundance after NI application (R<sup>2</sup> = 0.037, n = 136, P = 0.014). …”
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62099
There is a high-risk window early in treatment when missing doses is more likely to cause <i>de novo</i> resistance.
Published 2015“…Together these changes cause Φ<sub><i>m</i></sub> to increase initially and then to decrease exponentially at longer times (as seen in panel A).…”
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62100
Image_5_Bacteroides fragilis Prevents Clostridium difficile Infection in a Mouse Model by Restoring Gut Barrier and Microbiome Regulation.JPEG
Published 2019“…Notably, the abundance of Bacteroides fragilis was reported to be significantly decreased in CDAD patients. This study aimed to clarify the prophylactic effects of B. fragilis strain ZY-312 in a mouse model of C. difficile infection (CDI). …”