Metabolic Signatures of Extreme Longevity in Northern Italian Centenarians Reveal a Complex Remodeling of Lipids, Amino Acids, and Gut Microbiota Metabolism by Sebastiano Collino (385873)

“…With increasing age, targeted MS profiling of blood serum displayed a marked decrease in tryptophan concentration, while an unique alteration of specific glycerophospholipids and sphingolipids are seen in the longevity phenotype. …”

Supplementary Material for: Impact of the COVID-19 Pandemic on Gastroenterology Department Activity: The Gastroenterologist’s Perspective Nationwide and the Real Impact in a Portug... by RibeiroGomes A.C. (11163993)

“…Our aim is to evaluate the national gastroenterologists’ perspective on the impact of COVID-19 and the impact of reorganization of a gastroenterology department during the COVID-19 pandemic. …”

Presentation_1_A numerical study of the mixing and stratification alterations in estuaries due to climate change using the potential energy anomaly.pdf by Jagoba Lupiola (16623891)

“…On the other hand, climate change will generate lower precipitations and higher temperatures, decreasing runoff events. This phenomenon will decrease the freshwater input to the estuary and increase the tidal excursion along the estuary, producing a displacement of the river/estuarine front upstream of the areas.…”

A Cardiac-Specific Robotized Cellular Assay Identified Families of Human Ligands as Inducers of PGC-1α Expression and Mitochondrial Biogenesis by Matthieu Ruiz (130111)

“…This is associated with a decrease in the expression of the transcriptional coactivator PGC-1α, which plays a key role in the coordination of energy metabolism. …”

Data Sheet 1_Intergenerational metabolic toxicity of perfluorooctanesulfonic acid exposure in adult offspring rats: a multi-omics approach.docx by Guoqi Yu (5581436)

“…</p>Results<p>Early-life exposure to 0.03 mg/kg PFOS was found to be associated with elevated fasting and 15-minute blood glucose, serum insulin, and adiponectin levels and a decrease of leptin level in dose of 0.3 mg/kg was observed. …”

Table_1_Age Associated Microbiome and Microbial Metabolites Modulation and Its Association With Systemic Inflammation in a Rhesus Macaque Model.pdf by Suresh Pallikkuth (430427)

“…<p>Aging is associated with declining immunity and inflammation as well as alterations in the gut microbiome with a decrease of beneficial microbes and increase in pathogenic ones. …”

A Comparative Proteomic Study of Human Skin Suction Blister Fluid from Healthy Individuals Using Immunodepletion and iTRAQ Labeling by André C. Müller (1796518)

“…The use of iTRAQ 8-plex resulted in a 66% decrease in protein identifications but, despite this, provided valuable insight into interindividual differences of the healthy control samples. …”

Image 1_The activity of cell-free supernatant of Lactobacillus crispatus M247: a promising treatment against vaginal infections.png by Giulia Santarelli (14246638)

“…We observed a slight decrease in the microbial burden following LcM247 administration, while treatment with CFS significantly reduced microbial growth compared to control and antimicrobial compounds. …”

Table_2_Age Associated Microbiome and Microbial Metabolites Modulation and Its Association With Systemic Inflammation in a Rhesus Macaque Model.pdf by Suresh Pallikkuth (430427)

“…<p>Aging is associated with declining immunity and inflammation as well as alterations in the gut microbiome with a decrease of beneficial microbes and increase in pathogenic ones. …”

Image 6_Risk factors for thoracic aortic aneurysm and dissection among diabetic patients: a nationwide population-based study.tif by Suk Kyung Lim (22382302)

“…Meanwhile, the risk of TAAD was decreased in patients with a longer diabetes duration (HR: 0.97, 95% CI: 0.96–0.99) and metformin use (HR: 0.91 95% CI: 0.85–0.97).…”

Data Sheet 1_The role of statins in dementia or Alzheimer’s disease incidence: a systematic review and meta-analysis of cohort studies.docx by Ye Du (4067569)

“…Similarly, an analysis of 19 studies comprising 1,237,341 participants demonstrated a 29% decrease in the risk of AD among statin users (HR: 0.71, 95% CI: 0.60–0.85). …”

Table_5_Nutrient Scarcity in a New Defined Medium Reveals Metabolic Resistance to Antibiotics in the Fish Pathogen Piscirickettsia salmonis.pdf by Javiera Ortiz-Severín (8273808)

“…The mechanism for antibiotic resistance to ampicillin in the defined medium was further explored and was proven to be associated to a decrease in the bacterial central metabolism, including the TCA cycle, the pentose-phosphate pathway, energy production, and nucleotide metabolism, and it was not associated with decreased growth rate of the bacterium or with the expression of any predicted ARG. …”

Data_Sheet_1_Surgical outcomes and risk factors for overall mortality in brain arteriovenous malformations patients: a retrospective analysis.docx by Ioana Miron (19465333)

“…Multiple venous drainage was associated with a higher risk of worsened early outcome. Eloquent brain region involvement, conservative treatment, increasing age, admission mRS > 2, and comorbidities significantly decrease survival in brain AVM patients. …”

Table_1_Impact of the COVID-19 Pandemic Lockdown on Routine Childhood Immunization: A Saudi Nationwide Cross-Sectional Study.DOCX by Leena R. Baghdadi (9088967)

“…</p><p>Methods: We conducted a cross-sectional study using a self-administered survey that targeted primary caregivers of children aged ≤ 2 years residing in Saudi Arabia during the COVID-19 pandemic curfew (March 4–July 6, 2020).…”

Data_Sheet_1_Shifting Valproic Acid to Levetiracetam in Women of Childbearing Age With Epilepsy: A Retrospective Investigation and Review of the Literature.xlsx by Cheng-Yen Kuo (8761644)

“…The primary outcome was successful switching, which was defined as a decrease in the daily valproic acid dosage, after levetiracetam had been added.…”

Image_4_Bacteroides fragilis Prevents Clostridium difficile Infection in a Mouse Model by Restoring Gut Barrier and Microbiome Regulation.JPEG by Huimin Deng (1844299)

“…Notably, the abundance of Bacteroides fragilis was reported to be significantly decreased in CDAD patients. This study aimed to clarify the prophylactic effects of B. fragilis strain ZY-312 in a mouse model of C. difficile infection (CDI). …”

Image_1_Intra-Annual Variation in Mesophotic Benthic Assemblages on the Insular Slope of Southwest Puerto Rico as a Function of Depth and Geomorphology.JPEG by Richard S. Appeldoorn (7058471)

“…As a consequence, the differences in community structure with depth were larger at El Hoyo than at Hole-in-the-Wall. …”

DataSheet_1_The alterations of oral, airway and intestine microbiota in chronic obstructive pulmonary disease: a systematic review and meta-analysis.docx by Ziwei Kou (18518559)

“…However, the abundance of Haemophilus, Lactobacillus and Pseudomonas genera exhibited an increase, whereas Actinomyces and Porphyromonas showed a decrease in the airway microbiota of AECOPD compared to HC. …”

Data_Sheet_1_Effects of Oats (Avena sativa L.) on Inflammation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.docx by Sun Jo Kim (7072262)

“…</p><p>Conclusions: Overall evidence supporting the alleviation of inflammatory response by oat intake was poor, calling for future studies including a larger sample size to confirm the findings.</p>…”

DataSheet_2_The alterations of oral, airway and intestine microbiota in chronic obstructive pulmonary disease: a systematic review and meta-analysis.xlsx by Ziwei Kou (18518559)

“…However, the abundance of Haemophilus, Lactobacillus and Pseudomonas genera exhibited an increase, whereas Actinomyces and Porphyromonas showed a decrease in the airway microbiota of AECOPD compared to HC. …”