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62601
Image_4_Targeting Myeloid-Derived Suppressor Cells to Enhance a Trans-Sialidase-Based Vaccine Against Trypanosoma cruzi.pdf
Published 2021“…We previously showed that a trans-sialidase based vaccine (TSf-ISPA) is able to confer protection against a virulent T. cruzi strain, stimulating the effector immune response and decreasing CD11b+ GR-1+ splenocytes significantly. …”
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62602
Image_7_Measurement of the burdens of neonatal disorders in 204 countries, 1990–2019: a global burden of disease-based study.jpg
Published 2024“…Previous studies were based on limited data sources and had a narrow geographical scope. We aim to understand the trends of alteration in the burden of neonatal disorders from 1990 to 2019 in 204 countries and territories.…”
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62603
Table1_Safety evaluation of medroxyprogesterone acetate: a pharmacovigilance analysis using FDA adverse event reporting system data.DOCX
Published 2025“…Background<p>Medroxyprogesterone acetate (MPA), a synthetic progestogen, is extensively used for the treatment of various conditions, including contraception, irregular menstruation, functional uterine bleeding, and endometriosis. …”
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62604
Image_1_Targeting Myeloid-Derived Suppressor Cells to Enhance a Trans-Sialidase-Based Vaccine Against Trypanosoma cruzi.pdf
Published 2021“…We previously showed that a trans-sialidase based vaccine (TSf-ISPA) is able to confer protection against a virulent T. cruzi strain, stimulating the effector immune response and decreasing CD11b+ GR-1+ splenocytes significantly. …”
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62605
Image_2_Targeting Myeloid-Derived Suppressor Cells to Enhance a Trans-Sialidase-Based Vaccine Against Trypanosoma cruzi.pdf
Published 2021“…We previously showed that a trans-sialidase based vaccine (TSf-ISPA) is able to confer protection against a virulent T. cruzi strain, stimulating the effector immune response and decreasing CD11b+ GR-1+ splenocytes significantly. …”
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62606
Table_1_To develop a prognostic model for neoadjuvant immunochemotherapy efficacy in esophageal squamous cell carcinoma by analyzing the immune microenvironment.docx
Published 2024“…Dynamic mIF analysis also indicated that CD3+, CD8+, and CD20+ all increased after treatment in both groups, with a more significant increase in CD8+ and CD20+ in the Response group (P < 0.05), and a more significant decrease in PD-L1+ (P < 0.05). …”
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62607
Table_1_Seasonal variation in the detection rate and all-cause in-hospital mortality of AKI in China: A nationwide cohort study.pdf
Published 2022“…Background<p>Acute kidney injury (AKI) is a severe clinical syndrome that places a massive burden on medical systems worldwide, yet the seasonality of AKI remains unexplored in China. …”
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62608
Cancer therapy and risk of congenital malformations in children fathered by men treated for testicular germ-cell cancer: A nationwide register study
Published 2019“…Children conceived before a specific treatment acted as reference for children conceived after the same treatment. …”
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62609
High-intensity focused ultrasound (HIFU) therapy for benign thyroid nodules: a 3-year retrospective multicenter follow-up study
Published 2020“…No change in thyroid function was registered.</p> <p> HIFU carried a low risk of complications. A single treatment resulted in a 30–35% thyroid nodule volume decrease within one year, reduction that remained stable for 2 years. …”
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62610
Aortic Valve Replacement With Right Anterior Thoracotomy, Sutureless Valves, and Ultrafast-Track Anesthesia: A Truly Minimally Invasive Approach in Ancona
Published 2018“…In this video, the authors share their approach in a step-by-step fashion. The approach involves a right anterior minithoracotomy, the implantation of a sutureless LivaNova Perceval® S Valve, and the use of fast-track anesthetic protocols.…”
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62611
Image_2_Measurement of the burdens of neonatal disorders in 204 countries, 1990–2019: a global burden of disease-based study.jpg
Published 2024“…Previous studies were based on limited data sources and had a narrow geographical scope. We aim to understand the trends of alteration in the burden of neonatal disorders from 1990 to 2019 in 204 countries and territories.…”
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62612
Data_Sheet_2_Methylprednisolone Pulses in Hospitalized COVID-19 Patients Without Respiratory Failure: A Randomized Controlled Trial.pdf
Published 2022“…The primary outcome was treatment failure at 14 days, a composite variable including mortality, the need for ICU admission or mechanical ventilation, and clinical worsening, this last parameter defined as a PaO<sub>2</sub>/FiO<sub>2</sub> ratio below 300; or a 15% decrease in the PaO<sub>2</sub> from baseline, together with an increase in inflammatory markers or radiological progression. …”
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62613
Interaction of Asn297-Linked Glycan Ligands with the Fc Fragment of the Immunoglobulin Class G1: A Molecular Dynamics Simulation Study
Published 2024“…The results revealed that the STAB19 protein has a significantly higher affinity for L3 (−11.38 ± 2.32 kcal/mol) than that for L4 (−5.51 ± 1.92 kcal/mol). …”
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62614
Image_6_Measurement of the burdens of neonatal disorders in 204 countries, 1990–2019: a global burden of disease-based study.jpg
Published 2024“…Previous studies were based on limited data sources and had a narrow geographical scope. We aim to understand the trends of alteration in the burden of neonatal disorders from 1990 to 2019 in 204 countries and territories.…”
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62615
Data_Sheet_1_Methylprednisolone Pulses in Hospitalized COVID-19 Patients Without Respiratory Failure: A Randomized Controlled Trial.docx
Published 2022“…The primary outcome was treatment failure at 14 days, a composite variable including mortality, the need for ICU admission or mechanical ventilation, and clinical worsening, this last parameter defined as a PaO<sub>2</sub>/FiO<sub>2</sub> ratio below 300; or a 15% decrease in the PaO<sub>2</sub> from baseline, together with an increase in inflammatory markers or radiological progression. …”
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62616
The Effects of the Mediterranean Diet on Biomarkers of Vascular Wall Inflammation and Plaque Vulnerability in Subjects with High Risk for Cardiovascular Disease. A Randomized Trial
Published 2014“…</p><p>Results</p><p>Compared to participants in the low-fat diet group, those receiving MD+EVOO and MD+Nuts showed a higher decrease in systolic (6<b> </b>mmHg) and diastolic (3<b> </b>mmHg) blood pressure (P = 0.02; both), as well as a reduction of 10% and 8% in LDL-cholesterol (P = 0.04), respectively. …”
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62617
Table1_Safety evaluation of medroxyprogesterone acetate: a pharmacovigilance analysis using FDA adverse event reporting system data.DOCX
Published 2024“…Background<p>Medroxyprogesterone acetate (MPA), a synthetic progestogen, is extensively used for the treatment of various conditions, including contraception, irregular menstruation, functional uterine bleeding, and endometriosis. …”
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62618
Image_3_Targeting Myeloid-Derived Suppressor Cells to Enhance a Trans-Sialidase-Based Vaccine Against Trypanosoma cruzi.pdf
Published 2021“…We previously showed that a trans-sialidase based vaccine (TSf-ISPA) is able to confer protection against a virulent T. cruzi strain, stimulating the effector immune response and decreasing CD11b+ GR-1+ splenocytes significantly. …”
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62619
Malaria severity: Possible influence of the E670G PCSK9 polymorphism: A preliminary case-control study in Malian children
Published 2018“…<div><p>Aim</p><p>Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a hepatic secretory protein which promotes the degradation of low-density lipoprotein receptors leading to reduced hepatic uptake of plasma cholesterol. …”
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62620