Presentation 1_Impact of comorbid constipation on the survival of patients with heart failure: a multicenter, prospective cohort study conducted in Japan.pptx by Tomoaki Ishida (10687183)

“…Although the causal link between constipation and decreased survival remains unclear, identifying comorbid constipation is essential for identifying heart failure patients at a higher risk of poor outcomes.…”

Data_Sheet_1_Sex differences in the neuronal transcriptome and synaptic mitochondrial function in the cerebral cortex of a multiple sclerosis model.pdf by Noriko Itoh (17325616)

“…This is consistent with worse neurodegeneration in MS men and reveals a model and a target to develop treatments to prevent cortical neurodegeneration and mitigate disability progression in MS men.…”

DataSheet_1_Dietary Modification for Reproductive Health in Women With Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis.pdf by Yujie Shang (11630293)

“…Risk ratios and mean difference with 95% confidence intervals were assessed by a random-effects model. Statistical heterogeneity within comparisons was evaluated by Cochran’s Q test and quantified by the I-squared (I²) statistic.…”

Data_Sheet_1_A Pilot Assessment on the Role of Procalcitonin Dynamic Monitoring in the Early Diagnosis of Infection Post Cardiac Surgery.PDF by Qiang Miao (497115)

“…Purpose<p>To evaluate the value of dynamic monitoring of procalcitonin (PCT) as a biomarker for the early diagnosis of postoperative infections in patients undergoing cardiac surgery.…”

Image1_Neurological adverse events associated with oxaliplatin: A pharmacovigilance analysis based on FDA adverse event reporting system.JPEG by Xianglin Pan (4441699)

“…Time-to-onset and univariate logistic regression analysis were performed to describe the characteristics and risk factors of oxaliplatin-associated neurological adverse events.</p>Results<p>A total of 4,471 cases of oxaliplatin-associated neurological adverse events were identified, with 318 neurological adverse events being documented, among which 87 adverse events satisfied the thresholds of four methodologies. …”

Image_1_Treatment of Metastatic Primary Extramammary Paget Disease With Combination Anlotinib and Tislelizumab: A Case Report and Review of the Literature.PNG by Xin Yin (149454)

“…Total positron emission tomography and computed tomography (PET-CT) scans revealed a significant reduction in SUV from 18.9 to 5.3, and the serum CEA decreased to normal levels after the treatment regimen. …”

DataSheet3_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.pdf by Yongming Du (807059)

“…</p>Conclusion<p>This comprehensive MR analysis indicated that SLE, CeD, vitiligo, and AD caused an increased risk of POI, SIgAD was associated with a decreased risk of POI. These insights carry profound clinical implications, particularly emphasizing the early intervention for women with AIDs/POI who wish to preserve their reproductive potential or plan for future pregnancies.…”

Data_Sheet_1_A Quantitative Clinicopathological Signature for Predicting Recurrence Risk of Pancreatic Ductal Adenocarcinoma After Radical Resection.pdf by Chaobin He (1418719)

“…Least absolute shrinkage and selection operator (LASSO) and Cox regression were applied to assess the prognostic factors for overall survival (OS) and progression-free survival (PFS). A total of 302 patients were included into present study, and 173 patients were documented as recurrence after a median survival of 24.7 months. …”

Supplementary Material for: M6A RNA methylation-mediated dysregulation of AGAP2-AS1 promotes trastuzumab resistance of breast cancer by Cai Y. (4123975)

“…The m6A methylation of AGAP2-AS1 was found to be reduced in trastuzumab resistant cells compared to parental cells. …”

Table 1_Short-term influence of Immufen™ on mild allergic rhinitis: a randomized, double-blind, placebo-controlled study.docx by Mamatha K (19843110)

“…Introduction<p>Allergic rhinitis (AR) is an IgE-mediated reaction to inhaled allergens, and is a prominent health concern affecting approximately 400 million people worldwide. …”

Table_1_Depressive rumination and heart rate variability: A pilot study on the effect of biofeedback on rumination and its physiological concomitants.docx by Andy Schumann (8397531)

“…</p>Materials and methods<p>Sixteen patients suffering from depression completed a 6-week HRV-biofeedback training and fourteen patients completed a control condition in which there was no intervention (waitlist). …”

Table_2_A crucial exosome-related gene pair (AAMP and ABAT) is associated with inflammatory cells in intervertebral disc degeneration.docx by Huiyong Ren (5819255)

“…These results demonstrated the ERGP AAMP/ABAT as a robust signature for identifying IDD and associated with increased CD8⁺ T cell infiltration, suggesting it as a promising IDD biomarker.…”

Data_Sheet_1_Microbial Community and in situ Bioremediation of Groundwater by Nitrate Removal in the Zone of a Radioactive Waste Surface Repository.pdf by Alexey V. Safonov (5677793)

“…<p>The goal of the present work was to investigate the physicochemical and radiochemical conditions and the composition of the microbial community in the groundwater of a suspended surface repository for radioactive waste (Russia) and to determine the possibility of in situ groundwater bioremediation by removal of nitrate ions. …”

DataSheet1_Discovery of novel eGFR-associated multiple independent signals using a quasi-adaptive method.pdf by Sahar Ghasemi (14031774)

“…<p>A decreased estimated glomerular filtration rate (eGFR) leading to chronic kidney disease is a significant public health problem. …”

Image2_Periplaneta americana extract alleviates steatohepatitis in a mouse model by modulating HMGB1-mediated inflammatory response.tif by Yang Xiao (146335)

“…Periplaneta americana has a long history of being applied in medicine, including wound healing, antitumor, antibacterial, antiviral, antifibrotic, and cardiomyocyte-protecting. …”

Data_Sheet_1_A Mouse-Adapted Model of HCoV-OC43 and Its Usage to the Evaluation of Antiviral Drugs.ZIP by Peifang Xie (8806124)

“…Furthermore, treating with QJM or ARB raised the P9-infected mice’s survival rate within a 15 day observation period. These findings suggested that the new mouse-adapted HCoV-OC43 model is applicable and reproducible for antiviral studies of HCoV-OC43.…”

Supplementary file 1_Clinical efficacy and safety of acupuncture in the treatment for chronic spontaneous urticaria: a systematic review and meta-analysis.docx by Wang Wei (2074669)

“…Objective<p>This study aims to systematically evaluate the clinical efficacy and safety of acupuncture in treatment for chronic spontaneous urticaria (CSU) and provide evidence to inform clinical decision-making.</p>Methods<p>A comprehensive search of eight Chinese and English databases was carried out. …”

Table_2_Identification of Aortic Proteins Involved in Arterial Stiffness in Spontaneously Hypertensive Rats Treated With Perindopril:A Proteomic Approach.DOCX by Danyelle S. Miotto (10122521)

“…After perindopril treatment, there was an upregulation of the GDP dissociation inhibitors (GDIs), which normally inhibits the RhoA/Rho-kinase/cofilin-1 pathway and may contribute to decreased arterial stiffening. …”

Suppression of Mitochondrial Electron Transport Chain Function in the Hypoxic Human Placenta: A Role for miRNA-210 and Protein Synthesis Inhibition by Francesca Colleoni (278104)

“…Expression of HIF-responsive microRNA-210 was increased in hypoxic fibroblasts and high-altitude placentas, whilst expression of its targets, iron-sulfur cluster scaffold (ISCU) and cytochrome <em>c</em> oxidase assembly protein (COX10), decreased. Moreover, protein synthesis inhibition, a feature of the high-altitude placenta, also suppressed ETS complex protein levels. …”

New Insights on Cytological and Metabolic Features of <em>Ostreopsis</em> cf. <em>ovata</em> Fukuyo (Dinophyceae): A Multidisciplinary Approach by Giorgio Honsell (382702)

“…The HR LC-MS analysis reveals that ovatoxin-a is the predominant toxin, together with decreasing amounts of ovatoxin-b, -d/e, -c and putative palytoxin. …”