Image4_Periplaneta americana extract alleviates steatohepatitis in a mouse model by modulating HMGB1-mediated inflammatory response.tif by Yang Xiao (146335)

“…Periplaneta americana has a long history of being applied in medicine, including wound healing, antitumor, antibacterial, antiviral, antifibrotic, and cardiomyocyte-protecting. …”

A polyphenol-enriched diet and <i>Ascaris suum</i> infection modulate mucosal immune responses and gut microbiota composition in pigs by Andrew R. Williams (124412)

“…Both GP-supplementation and <i>A</i>. <i>suum</i> infection induced significant and apparently similar changes in the composition of the prokaryotic gut microbiota, and both also decreased concentrations of isobutyric and isovaleric acid (branched-chain short chain fatty acids) in the colon. …”

Erratum: GSK1614343, a Novel Ghrelin Receptor Antagonist, Produces an Unexpected Increase of Food Intake and Body Weight in Rodents and Dogs by Costantini V.J.A. (4272235)

“…In the present study, GSK1614343 (10 mg/kg) was not able to antagonize ghrelin-induced food consumption in rat, but unexpectedly stimulated FI and BW gain in both rats and dogs, a profile associated with decreased ghrelin plasma level. …”

Data_Sheet_1_Egg Consumption and Stroke Risk: A Systematic Review and Dose-Response Meta-Analysis of Prospective Studies.docx by Hui Tang (226667)

“…A decreased risk was observed for the intake of one to four eggs weekly and an increased risk for the intake of more than six eggs weekly. …”

The role of pioglitazone in antioxidant, anti-inflammatory, and insulin sensitivity in a high fat-carbohydrate diet-induced rat model of insulin resistance by H.M. Al-Muzafar (12728233)

“…<div><p>We explored the cascade effects of a high fat-carbohydrate diet (HFCD) and pioglitazone (an anti-diabetic therapy used to treat type 2 diabetes mellitus (T2DM)) on lipid profiles, oxidative stress/antioxidant, insulin, and inflammatory biomarkers in a rat model of insulin resistance. …”

Table_1_Functional Abnormality Associated With Tau Deposition in Alzheimer’s Disease – A Hybrid Positron Emission Tomography/MRI Study.DOCX by Liping Fu (296019)

“…Patients with a positive FC exhibited older ages, better cognitive performances, and a lower SUVR than patients with a negative FC.…”

Monitoring safety and use of old and new treatment options for type 2 diabetic patients: a two-year (2013–2016) analysis by Christian Leporini (3357902)

“…<p><b>Objective</b>: To compare patients’ and physicians’ perceptions regarding effectiveness and tolerability of non-insulin hypoglycemic drugs in a cohort of type 2 diabetic patients; to verify whether a possible tridimensional link between effectiveness, tolerability, and adherence affects long-term therapeutic outcomes.…”

Image 1_Cancer-associated fibroblasts gene signature: a novel approach to survival prediction and immunotherapy guidance in colon cancer.tif by Wenbing Zhang (152972)

“…The nomogram further effectively predicted the prognosis of COAD patients, with low-risk patients having a better prognosis. A higher immune infiltration rate and lower IC50 values of anticancer drugs were significant in the high-risk group. …”

Supplementary file 3_Clinical efficacy and safety of acupuncture in the treatment for chronic spontaneous urticaria: a systematic review and meta-analysis.docx by Wang Wei (2074669)

“…Objective<p>This study aims to systematically evaluate the clinical efficacy and safety of acupuncture in treatment for chronic spontaneous urticaria (CSU) and provide evidence to inform clinical decision-making.</p>Methods<p>A comprehensive search of eight Chinese and English databases was carried out. …”

Image5_Periplaneta americana extract alleviates steatohepatitis in a mouse model by modulating HMGB1-mediated inflammatory response.tif by Yang Xiao (146335)

“…Periplaneta americana has a long history of being applied in medicine, including wound healing, antitumor, antibacterial, antiviral, antifibrotic, and cardiomyocyte-protecting. …”

DataSheet1_A real-world disproportionality analysis of apalutamide: data mining of the FDA adverse event reporting system.doc by Zhihong Fang (407498)

“…<p>Background: Apalutamide is a new drug class, which is approved to treat prostate cancer (PCa). …”

DataSheet5_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.pdf by Yongming Du (807059)

“…</p>Conclusion<p>This comprehensive MR analysis indicated that SLE, CeD, vitiligo, and AD caused an increased risk of POI, SIgAD was associated with a decreased risk of POI. These insights carry profound clinical implications, particularly emphasizing the early intervention for women with AIDs/POI who wish to preserve their reproductive potential or plan for future pregnancies.…”

Data_Sheet_1_N-Glycosylation Regulates the Trafficking and Surface Mobility of GluN3A-Containing NMDA Receptors.pdf by Kristyna Skrenkova (5332883)

“…Finally, we found that the surface mobility of GluN3A-containing NMDARs in hippocampal neurons is increased following incubation with 1-deoxymannojirimycin (DMM, an inhibitor of the formation of the hybrid/complex forms of N-glycans) and decreased in the presence of specific lectins. …”

Identification of a novel gene in ROD9 island of <i>Salmonella</i> Enteritidis involved in the alteration of virulence-associated genes expression by Susmita Das (732385)

“…Additionally, the global transcriptome analysis revealed a highly repressed SPI-1 and other down-regulated genes responsible for flagellar assembly, chemotaxis and motility in the mutant which correlated with decreased invasion and abated inflammation as compared to the wild-type. …”

Data_Sheet_1_Fontan Circulation Associated Organ Abnormalities Beyond the Heart, Lungs, Liver, and Gut: A Systematic Review.docx by Evi Ritmeester (12273122)

“…Introduction<p>Patients with a Fontan circulation are at risk for sequelae of Fontan physiology during follow-up. …”

DataSheet1_Sex, Pramipexole and Tiagabine Affect Behavioral and Hormonal Response to Traumatic Stress in a Mouse Model of PTSD.docx by Natalia Malikowska-Racia (10875226)

“…<p>Posttraumatic stress disorder (PTSD) has been associated with abnormal regulation of the hypothalamic-pituitary-adrenal gland axis (HPA). Women demonstrate a more robust HPA response and are twice as likely to develop PTSD than men. …”

DataSheet_1_The Efficacy of Denosumab in Patients With Rheumatoid Arthritis: A Systematic Review and Pooled Analysis of Randomized or Matched Data.docx by Qiongwen Hu (11904590)

“…</p>Results<p>After searching the literature and performing further detailed assessments, 10 studies with a total of 1758 patients were included in the quantitative analysis. …”

Inner Ear Development Across Onset and Improvement of Escape-Hatching Ability in Red-Eyed Treefrogs: a Confocal and µCT Analysis by Julie Jung (8539041)

“…Arboreal embryos of red-eyed treefrogs, Agalychnis callidryas, hatch to escape from egg predators, cued by physical disturbance in attacks. A developmental match in the onset of otic function, measured by the vestibulo-ocular reflex (VOR), and mechanosensory-cued hatching (MCH) suggests that inner ear mechanoreceptors mediate this response. …”

Table1_Case report: A case of Rabson–Mendenhall syndrome: long-term follow-up and therapeutic management with empagliflozin.XLSX by R. Foglino (18870559)

“…</p><p>Results: After 10 months of treatment, empagliflozin therapy led to a clinically meaningful reduction in HbA1c levels, decreasing from 8.5% to 7.1%, along with an improvement in TIR from 47% to 74%. …”

Table_1_Sustained Intermittent Hypoxemia Induces Adiponectin Oligomers Redistribution and a Tissue-Specific Modulation of Adiponectin Receptor in Mice.DOCX by Mélany Pierard (3443489)

“…Mice submitted to hypoxia also exhibited tissue-specific modification of adiporeceptor (AdipoR) protein level without mRNA expression change. A decreased AdipoR2 abundance was observed in skeletal muscle and heart whereas AdipoR1 level was only reduced in muscle. …”