Study on the Multimodal Anticancer Mechanism of Ru(II)/Ir(III) Complexes Bearing a Poly(ADP-ribose) Polymerase 1 Inhibitor by Yuliang Yang (1954498)

“…A series of novel ruthenium­(II) and iridium­(III) complexes (<b>Ru1</b>–<b>Ru3</b> and <b>Ir1</b>–<b>Ir3</b>) with different ancillary ligands and a PARP-1-inhibitory chelating ligand 2-(2,3-dibromo-4,5-dimethoxybenzylidene)­hydrazine-1-carbothioamide (<b>L1</b>) were designed and prepared. …”

Data_Sheet_1_A Possible Role of Allatostatin C in Inhibiting Ecdysone Biosynthesis Revealed in the Mud Crab Scylla paramamosain.doc by An Liu (291211)

“…In addition, qRT-PCR showed that both ScypaAST-C and ScypaAST-CCC significantly decreased the level of expression of the MF biosynthetic enzyme gene in the mandibular organ, suggesting that the two neuropeptides have a negative effect on the MF biosynthesis in mandibular organs. …”

Image_1_Efficacy and Safety of Lactobacillus reuteri CCFM1040 in Allergic Rhinitis and Asthma: A Randomized, Placebo-Controlled Trial.TIF by Lingzhi Li (1758493)

“…This study presented a randomized, placebo-controlled trial to investigate the clinical effects of CCFM1040 on both diseases. …”

Assessing Cue-Induced Brain Response as a Function of Abstinence Duration in Heroin-Dependent Individuals: An Event-Related fMRI Study by Qiang Li (8118)

“…<div><p>The brain activity induced by heroin-related cues may play a role in the maintenance of heroin dependence. …”

Systems Modeling of Anti-apoptotic Pathways in Prostate Cancer: Psychological Stress Triggers a Synergism Pattern Switch in Drug Combination Therapy by Xiaoqiang Sun (493308)

“…Moreover, we found that epinephrine signaling changes the synergism pattern and decreases efficacy of combination therapy. The molecular mechanisms responsible for therapeutic resistance and the switch in synergism were explored by analyzing a network model of signaling pathways affected by psychological stress. …”

Short- and long-term effects of remote synchronous fine-tuning for first-time hearing aid users: a randomised controlled trial by Milijana Malmberg (5682503)

“…<p>To evaluate the short- and long-term effect of remote synchronous fine-tuning and follow-up visits on hearing-related problems and hearing aid (HA) benefits for first-time HA users.</p> <p>A randomised controlled trial.</p> <p>Patients at public tax-funded HA clinics in Sweden due for aural rehabilitation (AR) were randomised to either an intervention group (n = 33) or a control group (n = 36). …”

Alterations in nasal airflow and air conditioning after endoscopic nasopharyngectomy for recurrent nasopharyngeal carcinoma: a pilot computational fluid dynamics study by Dong Dong (23216)

“…<p>Endoscopic nasopharyngectomy represents a significant intervention for recurrent nasopharyngeal carcinoma (NPC). …”

Table_2_Development of a High-Throughput Microfluidic qPCR System for the Quantitative Determination of Quality-Relevant Bacteria in Cheese.XLSX by Matthias Dreier (9949835)

“…High-throughput qPCR (HT-qPCR) using microfluidics brings further advantages by providing fast results and by decreasing the cost per sample. We have developed a HT-qPCR approach for the rapid and cost-efficient quantification of microbial species in cheese by designing qPCR assays targeting 24 species/subspecies commonly found in cheese. …”

Effect of 4‑HNE Modification on ZU5-ANK Domain and the Formation of Their Complex with β‑Spectrin: A Molecular Dynamics Simulation Study by Antistio Alviz-Amador (8174016)

“…However, effects at the atomic level of this carbonylation on structure and function of modified protein are not yet fully understood. We present a study based on molecular dynamics simulations of nine 4-HNE modified residues of the ZU5-ANK ankyrin domain with β-spectrin and their binding energy profiles. …”

Data Sheet 15_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.pdf by Didar Murad (12220805)

“…To understand the essential balance between activation and regulation of these systems, a quantitative systems immunology model can be established. …”

Image 5_Photon budgets and the relative effects of CDOM and pigment absorptions on primary production along a coastal salinity gradient.jpeg by Aleksandr Berezovski (20548583)

“…The absorption by CDOM and detritus decreased with increasing salinity, while phytoplankton absorption followed a seasonal succession. …”

L-165041 protects H9c2 from doxorubicin-induced apoptosis through a Bcl6-independent mechanism. by Paola Altieri (305752)

“…<p>(A) Pre-treatment with L-165141decreases the number of doxorubicin-induced apoptotic cells. …”

Nitrogen and phosphorus uptake efficiency in Indian mustard cultivated during three growth cycles in a copper contaminated soil treated with biochar by Maria Isidória Silva Gonzaga (6301118)

“…Biochar did not affect P nutrition in Indian mustard to a great extent; however, it significantly decreased the N:P ratio in the plant.…”

Table_3_Quantitative Proteomics Reveals Common and Specific Responses of a Marine Diatom Thalassiosira pseudonana to Different Macronutrient Deficiencies.XLSX by Xiao-Huang Chen (5139608)

“…Contents of chlorophyll a, protein and cellular N decreased in both N- and P-deficient cells but chlorophyll a and cellular N increased in the Si-deficient cells. …”

Table4_The central mechanisms of electroacupuncture at LR3 in the treatment of spontaneous hypertension: a PET and mRNA transcriptome study.xlsx by Jing Li (10611)

“…PET-CT revealed that EA decreased glucose metabolism in the hypothalamus. Genomic analysis suggested that, compared to the SHR group, the differentially expressed genes in the hypothalamus of the EA group included Nr4a1, Sirt1, Trh, GPR88, Cck, and Th. …”

Image_1_SnakeStrike: A Low-Cost Open-Source High-Speed Multi-Camera Motion Capture System.JPEG by Grady W. Jensen (9198731)

“…It supports researchers with a performance-optimized suite of functions that encompass the entirety of data collection and decreases processing time for high-speed 3D position tracking on a variety of animals, including snakes. …”

Data_Sheet_1_A Novel Promazine Derivative Shows High in vitro and in vivo Antimicrobial Activity Against Staphylococcus aureus.docx by Troels Ronco (414344)

“…<p>The emergence of multidrug-resistant bacteria constitutes a significant public health issue worldwide. Consequently, there is an urgent clinical need for novel treatment solutions. …”

BACE1 Inhibition Induces a Specific Cerebrospinal Fluid β-Amyloid Pattern That Identifies Drug Effects in the Central Nervous System by Niklas Mattsson (144720)

“…In particular Aβ1-34 decreased, while Aβ5-40 increased, and these changes were more sensitive to BACE1 inhibition than the changes in Aβ1-40 and Aβ1-42. …”

DataSheet_1_Single-cell RNA-seq reveals a link of ovule abortion and sugar transport in Camellia oleifera.zip by Songzi Zhao (14662148)

“…Both the infertile ovule before pollination and the abortion ovule producing after compatible pollination might be attributed to selective abortion caused by low sugar levels in the apoplast around procambium cells and a low capability of hexose uptake in the integument. …”

The Csy1-3 and Cas6f proteins of <i>P. atrosepticum</i> form a complex <i>in vivo</i>. by Corinna Richter (295732)

“…<p>(A) Scale schematic representation of the CRISPR/Cas system in <i>P. atrosepticum</i> strain SCRI1043. …”