Table 1_Cancer-associated fibroblasts gene signature: a novel approach to survival prediction and immunotherapy guidance in colon cancer.docx by Wenbing Zhang (152972)

“…The nomogram further effectively predicted the prognosis of COAD patients, with low-risk patients having a better prognosis. A higher immune infiltration rate and lower IC50 values of anticancer drugs were significant in the high-risk group. …”

DataSheet7_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.pdf by Yongming Du (807059)

“…</p>Conclusion<p>This comprehensive MR analysis indicated that SLE, CeD, vitiligo, and AD caused an increased risk of POI, SIgAD was associated with a decreased risk of POI. These insights carry profound clinical implications, particularly emphasizing the early intervention for women with AIDs/POI who wish to preserve their reproductive potential or plan for future pregnancies.…”

Table2_A novel m7G methylation–related signature associated with chromosome homeostasis in patients with lung adenocarcinoma.XLSX by Xiaoying Tao (13999797)

“…The gene set enrichment analysis (ssGSEA) implied that the immune status was decreased in the high-risk group. To sum up, m7G methylation–related genes play a vital role in tumor immunity and the related signature is a reliable predictor for LUAD prognosis.…”

Identification of a Novel Potent CYP4Z1 Inhibitor Attenuating the Stemness of Breast Cancer Cells through Lead Optimization by Yin Yuan (597540)

“…Furthermore, it was found that <b>7c</b> decreased the expression of stemness markers, spheroid formation, and metastatic ability as well as tumor-initiation capability in a concentration-dependent manner in vitro and in vivo. …”

Data_Sheet_1_Bioremoval of Co(II) by a novel halotolerant microalgae Dunaliella sp. FACHB-558 from saltwater.xlsx by Chenglong Liu (317596)

“…FACHB-558 could grow under a salinity condition with 0.5–4.5 M NaCl. A phylogenetic analysis based on the rbcL gene revealed that Dunaliella sp. …”

Table 3_Validation of the orthostatic hypotension knowledge, attitudes, and practices questionnaire and investigation of influencing factors: a cross-sectional study.docx by Qin Zou (747755)

“…Receiving health education on OH also reduced the risk of low scores (OR: 0.36, 95% CI: 0.30–0.45). Additionally, a higher FES-I score was linked to a decreased risk of low KAPQ scores (OR: 0.98, 95% CI: 0.97–0.99).…”

Image_1_Not your usual neurodegenerative disease: a case report of neuronal intranuclear inclusion disease with unconventional imaging patterns.jpeg by Luyao Xu (3987749)

“…</p>Case presentation<p>A 39-year-old man presented with chronic headache, blurred vision, tinnitus, and numbness in the hands as initial symptoms, accompanied by cognitive slowing and decreased memory. …”

Table 1_Adverse events associated with vismodegib: insights from a real-world pharmacovigilance study using the FAERS database.docx by Bingqing Wang (6428924)

“…It not only confirms the known adverse events on the label, but also suggests several potential novel adverse events, thereby supporting a more informed and rational use of vismodegib in clinical practice.…”

DataSheet_1_Responses of terrestrial ecosystem productivity and community structure to intra-annual precipitation patterns: A meta-analysis.pdf by Mingyu Xie (13868310)

“…</p>Methods<p>We synthesized 633 observations from 17 studies and conducted a global meta-analysis to investigate the influences of intra-annual precipitation patterns on the productivity and community structures of terrestrial ecosystems. …”

A Targeted Glycan-Related Gene Screen Reveals Heparan Sulfate Proteoglycan Sulfation Regulates WNT and BMP Trans-Synaptic Signaling by Neil Dani (121036)

“…<div><p>A <em>Drosophila</em> transgenic RNAi screen targeting the glycan genome, including all N/O/GAG-glycan biosynthesis/modification enzymes and glycan-binding lectins, was conducted to discover novel glycan functions in synaptogenesis. …”

DataSheet_1_The antibacterial activity and mechanism of a novel peptide MR-22 against multidrug-resistant Escherichia coli.docx by Chunren Tian (13899051)

“…Introduction<p>Bacterial infections have become serious threats to human health, and the excessive use of antibiotics has led to the emergence of multidrug-resistant (MDR) bacteria. E. coli is a human bacterial pathogen, which can cause severe infectious. …”

Elevated Serum ADA Activity as a Marker for Diagnosis and Prognosis of Visceral Leishmaniasis and Post Kala-Azar Dermal Leishmaniasis in Indian Patients by Vijayamahantesh (3169728)

“…Since cell-mediated immune responses play a paramount role in the pathogenesis and healing of the visceral leishmaniasis, therefore, the present study was undertaken to evaluate the serum ADA activity in different pathological conditions. …”

Table 1_Longitudinal ozone exposure and SARS-CoV-2 infection in late pregnancy: a retrospective cohort study.docx by Lin Zhang (8926)

“…Compared to the lowest quartile (reference), the highest ozone quartile corresponded to a 99% decreased infection risk (OR = 0.01, 95% CI: 0.00-0.03). …”

Supplementary file 2_Clinical efficacy and safety of acupuncture in the treatment for chronic spontaneous urticaria: a systematic review and meta-analysis.docx by Wang Wei (2074669)

“…Objective<p>This study aims to systematically evaluate the clinical efficacy and safety of acupuncture in treatment for chronic spontaneous urticaria (CSU) and provide evidence to inform clinical decision-making.</p>Methods<p>A comprehensive search of eight Chinese and English databases was carried out. …”

C-type Lectin Mincle Recognizes Glucosyl-diacylglycerol of <i>Streptococcus pneumoniae</i> and Plays a Protective Role in Pneumococcal Pneumonia by Friederike Behler-Janbeck (3384488)

“…<i>pneumoniae</i>, all of which was normalized in Mincle KO mice reconstituted with a WT hematopoietic system. In conclusion, the Mincle-Glc-DAG axis is a hitherto unrecognized element of lung protective immunity against focal pneumonia induced by <i>S</i>. …”

Image_3_Safety and Efficacy of a Phage, kpssk3, in an in vivo Model of Carbapenem-Resistant Hypermucoviscous Klebsiella pneumoniae Bacteremia.TIF by Yunlong Shi (1652176)

“…In this study, the therapeutic effects and safety of kpssk3, a previously isolated phage infecting carbapenem-resistant hypermucoviscous Klebsiella pneumoniae (CR-HMKP), were evaluated in a mouse model of systemic CR-HMKP infection. …”

Table_1_Topical application of the plant extract SDTL-E in ovariectomized rats: A potential new approach for treating osteoporosis.DOCX by Hui-Yuan Shih (13985985)

“…These findings suggest topical application of plant extract is a potential new approach with quick efficacy for treating osteoporosis.…”

Image_2_Safety and Efficacy of a Phage, kpssk3, in an in vivo Model of Carbapenem-Resistant Hypermucoviscous Klebsiella pneumoniae Bacteremia.TIF by Yunlong Shi (1652176)

“…In this study, the therapeutic effects and safety of kpssk3, a previously isolated phage infecting carbapenem-resistant hypermucoviscous Klebsiella pneumoniae (CR-HMKP), were evaluated in a mouse model of systemic CR-HMKP infection. …”

DataSheet1_Efficacy and Safety of Various Treatments for Proliferative Diabetic Retinopathy: A Systematic Review and Network Meta-Analysis.DOCX by Bo Zhang (6559)

“…A total of 15 studies were selected, including 3,222 eyes of PDR patients. …”

Image1_Periplaneta americana extract alleviates steatohepatitis in a mouse model by modulating HMGB1-mediated inflammatory response.tif by Yang Xiao (146335)

“…Periplaneta americana has a long history of being applied in medicine, including wound healing, antitumor, antibacterial, antiviral, antifibrotic, and cardiomyocyte-protecting. …”