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63961
DataSheet_1_FGL1 as a Novel Mediator and Biomarker of Malignant Progression in Clear Cell Renal Cell Carcinoma.pdf
Published 2021“…<p>Clear cell renal cell carcinoma (ccRCC), which is the most prevalent renal cell carcinoma subtype, has a poor prognosis. Emerging strategies for enhancing the immune response in ccRCC therapy are currently being investigated. …”
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63962
Image_1_Spatial Changes in the Atrial Fibrillation Wave-Dynamics After Using Antiarrhythmic Drugs: A Computational Modeling Study.TIF
Published 2022“…<p>Background: We previously reported that a computational modeling-guided antiarrhythmic drug (AAD) test was feasible for evaluating multiple AADs in patients with atrial fibrillation (AF). …”
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63963
Association between dietary patterns and renal function in a cross-sectional study using baseline data from the ELSA-Brasil cohort
Published 2021“…The aim of this study was to explore the association between the previously defined DP and renal function (RF). A cross-sectional study using the ELSA-Brasil baseline data was carried out. …”
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63964
Image_8_Long-Term Overconsumption of Fat and Sugar Causes a Partially Reversible Pre-inflammatory Bowel Disease State.JPEG
Published 2021“…In healthy mice, a high-fat high-sucrose diet induces a pre-IBD state characterized by gut microbiota dysbiosis with a total depletion of bacteria belonging to Barnesiella that is associated with subclinical endoscopic lesions. …”
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63965
Image_3_A Novel Calcium-Activated Potassium Channel Controls Membrane Potential and Intracellular pH in Trypanosoma cruzi.TIF
Published 2020“…As predicted, a single point mutation in the selectivity filter (Y313A) completely abolished the activity of the channels, confirming its potassium selective nature. …”
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63966
Image4_Olaparib, a PARP-1 inhibitor, protects retinal cells from ocular hypertension-associated oxidative damage.jpg
Published 2022“…Additionally, some indicators of mitochondrial performance, such as reactive oxygen species accumulation, mitochondrial Ca<sup>2+</sup> influx, and mitochondrial membrane potential collapse, decreased after olaparib treatment. Olaparib attenuated the hypoxia-induced upregulation of NLRP3 protein levels as well as the phosphorylation of ERK1/2 and histone H2A.X. …”
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63967
Table_1_Transcriptome Profiling Reveals a Petunia Transcription Factor, PhCOL4, Contributing to Antiviral RNA Silencing.DOCX
Published 2022“…<p>RNA silencing is a common antiviral mechanism in eukaryotic organisms. …”
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63968
Data Sheet 1_Effects of aging and valence on emotional response inhibition: conclusions from a novel stop-signal task.pdf
Published 2025“…Participants completed a novel stop-signal task where pleasant and unpleasant scene images appeared on a minority of trials, while participants developed a pre-potent ‘go’ response during trials presenting neutral shapes. …”
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63969
Socioeconomic hardship, uncertainty about the future, and adolescent mental wellbeing over a year during the COVID-19 pandemic_Study Information
Published 2023“…<p dir="ltr">Study information on the article 'Socioeconomic hardship, uncertainty about the future, and adolescent mental wellbeing over a year during the COVID-19 pandemic'</p><p><br></p><p dir="ltr">Abstract | Socioeconomic vulnerabilities put adolescents at risk for mental wellbeing issues, also in times of a pandemic. …”
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63970
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63971
Image_2_CircCDYL Acts as a Tumor Suppressor in Wilms’ Tumor by Targeting miR-145-5p.TIF
Published 2021“…Mechanically, circCDYL, functioning as a miRNA sponge, decreased the expression level of miR-145-5p and TJP1 3′UTR was validated as the target of miR-145-5p, facilitating the circCDYL/miR-145-5p/TJP1 axis. …”
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63972
Table 1_Comparative efficacy and hematologic safety of different dosages of JAK inhibitors in the treatment of myelofibrosis: a network meta-analysis.docx
Published 2024“…PAC and MMB were associated with a decreased risk of grade 3/4 anemia and thrombocytopenia compared to other JAKis. …”
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63973
Table_12_Transcriptome Profiling Reveals a Petunia Transcription Factor, PhCOL4, Contributing to Antiviral RNA Silencing.docx
Published 2022“…<p>RNA silencing is a common antiviral mechanism in eukaryotic organisms. …”
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63974
Data_Sheet_1_Case report: Bilateral central serous chorioretinopathy-like abnormalities in a man with pulmonary arterial hypertension.pdf
Published 2022“…</p>Case summary<p>A 45-year-old man presented with decreasing central vision and metamorphopsia in both eyes. …”
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63975
Table_1_IL-1β Blockade Attenuates Thrombosis in a Neutrophil Extracellular Trap-Dependent Breast Cancer Model.docx
Published 2019“…On the other hand, mice bearing non-metastatic 67NR tumors showed no elevation in neutrophil counts and displayed low expression levels of G-CSF and IL-1β in their tumors. 4T1 tumor-bearing mice but not 67NR tumor-bearing mice exhibited a NET-dependent prothrombotic state. Pharmacological blockade of IL-1 receptor (IL-1R) decreased the primary growth of 4T1 tumors and reduced the systemic levels of myeloperoxidase, cell-free DNA (cfDNA) and G-CSF, without interfering with the neutrophil counts. …”
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63976
DataSheet1_Adverse event profiles of adjuvant treatment with opicapone in Parkinson’s disease: A systematic review and meta-analysis.PDF
Published 2022“…<p>Background: Opicapone, a novel third-generation catechol-O-methyltransferase inhibitor, has demonstrated efficacy in Parkinson’s Disease (PD) patients with end-of-dose motor fluctuations.…”
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63977
Detection of Venom after Antivenom Is Not Associated with Persistent Coagulopathy in a Prospective Cohort of Russell's Viper (<i>Daboia russelii</i>) Envenomings
Published 2014“…</p><p>Methodology/Principal Findings</p><p>The study included patients with Russell's viper (<i>D. russelii</i>) envenoming presenting over a 30 month period who had Russell's viper venom detected by enzyme immunoassay. …”
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63978
The Continuum of Physiological Impairment during Treadmill Walking in Patients with Mild-to-Moderate COPD: Patient Characterization Phase of a Randomized Clinical Trial
Published 2014“…<div><p>Background</p><p>To have a better understanding of the mechanisms of exercise limitation in mild-to-moderate chronic obstructive pulmonary disease (COPD), we compared detailed respiratory physiology in patients with COPD and healthy age- and sex-matched controls.…”
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63979
DataSheet1_How the Way a Naphthalimide Unit is Implemented Affects the Photophysical and -catalytic Properties of Cu(I) Photosensitizers.pdf
Published 2022“…In particular, the distinction between the effects of a covalently linked and a directly fused naphthalimide unit was assessed. …”
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63980
Table1_Cost-effectiveness analysis of pharmaceutical care in adult critically ill patients: based on a prospective cohort study.docx
Published 2024“…</p>Conclusions<p>Pharmaceutical care significantly reduces adverse drug events and medication errors, promotes rational use of medications, decreases the length of ICU stay, and lowers treatment costs in critically ill patients, establishing a definitive advantage in terms of cost-effectiveness.…”