Image_5_Urban Diets Linked to Gut Microbiome and Metabolome Alterations in Children: A Comparative Cross-Sectional Study in Thailand.TIF by Juma Kisuse (5437766)

TAC-induced CaMKIIδB activation and CaMKII-HDAC4 complex translocalization are blocked by a calmodulin antagonist. by Ying-Mei Lu (206101)

“…<p>(<b>A</b>) Representative hearts (upper) and H&E staining of heart tissues (lower) in mice treated with either a TAC or TAC+ calmodulin antagonist (DY-9836, 20 mg/kg for six weeks). …”

Table2_Inhibition of the Protein Arginine Methyltransferase PRMT5 in High-Risk Multiple Myeloma as a Novel Treatment Approach.XLSX by Philip Vlummens (221451)

“…Hence, protein arginine methyltransferase 5 (PRMT5) was identified as a promising target. Druggability was assessed in OPM2, JJN3, AMO1 and XG7 human myeloma cell lines using the PRMT5-inhibitor EPZ015938. …”

Data_Sheet_1_Selective enrichment of the raw milk microbiota in cheese production: Concept of a natural adjunct milk culture.docx by Luca Bettera (14393145)

“…Although the use of diverse eRWCs contributed to having a richer and more diverse microbiota in the early stages of cheese making, their effect decreased over time during ripening, showing an inferior effect to the raw milk microbiota. …”

Table_1_Establishment and validation of a bad outcomes prediction model based on EEG and clinical parameters in prolonged disorder of consciousness.DOCX by Wanqing Liu (25627)

“…</p>Result<p>The results from univariate and multivariate logistic regression analyses suggested that an increased frequency of occurrence microstate A, reduced CRS-R scores at the time of admission, the presence of episodes associated with paroxysmal sympathetic hyperactivity (PSH), and decreased fibrinogen levels all function as independent prognostic factors. …”

CYT-19–mediated unwinding of a shorter P1 helix (6 bp) is rate limited by spontaneous loss of tertiary contacts. by Cynthia Pan (650593)

“…Weakening P1 docking by atomic mutagenesis (blue, −3 m, rSA₅) increases <i>k</i>_max to 20 min⁻¹, and strengthening the docking contacts (green, rP, also in inset) decreases <i>k</i>_max to 0.075 min⁻¹ (<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1001981#pbio.1001981.s006" target="_blank">Figure S6</a> and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1001981#pbio.1001981.s010" target="_blank">Table S3</a>). …”

Table_2_Tumor cuproptosis and immune infiltration improve survival of patients with hepatocellular carcinoma with a high expression of ferredoxin 1.xlsx by Yingyao Quan (7105034)

“…Meanwhile, we found that a high expression of FDX1 decreased cell viability in HCC samples. …”

Image_2_Differential Modulation of Mouse Heart Gene Expression by Infection With Two Trypanosoma cruzi Strains: A Transcriptome Analysis.TIF by Tiago Bruno Rezende de Castro (9335921)

“…<p>The protozoan Trypanosoma cruzi (T. cruzi) is a well-adapted parasite to mammalian hosts and the pathogen of Chagas disease in humans. …”

Table1_Mechanisms Underlying the Effects of Lianhua Qingwen on Sepsis-Induced Acute Lung Injury: A Network Pharmacology Approach.DOCX by Ruhao Yang (11562034)

“…<p>Background and Purpose: Sepsis is a life-threatening condition associated with secondary multiple organ injury. …”

Evaluation of Methionine Content in a High-Fat and Choline-Deficient Diet on Body Weight Gain and the Development of Non-Alcoholic Steatohepatitis in Mice by Tsuyoshi Chiba (477300)

“…Liver weights and hepatic lipid contents were the greatest with 0.1% methionine and decreased in a methionine dose-dependent manner. Pathological analysis, NAFLD activity scores and gene expression levels in the liver revealed that 0.1% and 0.2% methionine for 12 weeks induced NASH, whereas 0.4% and 0.6% methionine attenuated the induction of NASH by HFCD diet. …”

Table 1_Temporal trends and demographic influences on protein-energy malnutrition in China: a comprehensive analysis from 1990 to 2021.docx by Zhouwei Zhan (18471500)

“…From 1990 to 2021, incidence and prevalence increased until 2015 and then declined, while mortality and DALYs steadily decreased, particularly among females. Compared to global trends, China demonstrated greater reductions in age-standardized mortality and DALYs, but a slight increase in incidence. …”

Table_2_Potential Drug-Drug Interactions in Patients With Urinary Tract Infections: A Contributing Factor in Patient and Medication Safety.docx by Sidra Noor (5852228)

“…</p><p>Conclusions: Patients with UTIs present with a considerable number of clinically important pDDIs. …”

Data_Sheet_1_Supplemental L-Arginine Improves the Embryonic Intestine Development and Microbial Succession in a Chick Embryo Model.docx by Dong Dai (696631)

“…The relative mRNA expressions of mTOR and 4E-BP1 were up-regulated and accompanied by higher contents of Mucin-2 in the Arg group (p < 0.05). There was a significant elevation in contents of serum glucose and high-density lipoprotein cholesterol, whereas there was a decreased low-density lipoprotein cholesterol in the Arg group (p < 0.05). …”

DataSheet_2_Proteomic Analysis Reveals a Novel Therapeutic Strategy Using Fludarabine for Steroid-Resistant Asthma Exacerbation.xlsx by Xiaoming Liu (47653)

“…<p>Virus-induced asthma exacerbation is a health burden worldwide and lacks effective treatment. …”

DataSheet_1_Proteomic Analysis Reveals a Novel Therapeutic Strategy Using Fludarabine for Steroid-Resistant Asthma Exacerbation.docx by Xiaoming Liu (47653)

“…<p>Virus-induced asthma exacerbation is a health burden worldwide and lacks effective treatment. …”

Data_Sheet_1_Soil carbon dynamics are linked to tree species growth strategy in a naturally regenerating tropical forest.docx by Abby Wallwork (8540469)

“…We experimentally explored the relationship between tree functional groups and soil C dynamics (decomposition and respiration) by conducting a litter decomposition experiment across a successional gradient of naturally regenerating tropical forest. …”

Elevated oxytocin and noradrenaline indicate higher stress levels in allergic rhinitis patients: Implications for the skin prick diagnosis in a pilot study by Jelena Gotovina (1332036)

“…Subsequently, participants were exposed to a standardized Trier Social Stress Test (TSST), followed by SPT on the contralateral forearm. …”

Effect of Molecular Structure on the B3LYP-Computed HOMO–LUMO Gap: A Structure −Property Relationship Using Atomic Signatures by Ahmed Mohamed (628889)

“…The atomic fragments containing π-bonds in various aromatic compounds were found to be the most significant atomic Signatures, explaining nearly 50% of the variance in the data, with regression coefficients that decreased <i>E</i>_gap. This is attributed to π-electron delocalization, making this molecular fragment a reactive site in a molecule. …”

Table_4_Urban Diets Linked to Gut Microbiome and Metabolome Alterations in Children: A Comparative Cross-Sectional Study in Thailand.XLSX by Juma Kisuse (5437766)

DataSheet_2_A Novel Mechanism of Carvedilol Efficacy for Rosacea Treatment: Toll-Like Receptor 2 Inhibition in Macrophages.docx by Jiawen Zhang (586977)

“…Background<p>Rosacea, a chronic inflammatory skin disorder etiologically associated with immune cells and the antibacterial peptide cathelicidin LL-37, can be effectively treated by oral carvedilol administration.…”