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8261
The Role of Genetically Modified Mesenchymal Stem Cells in Urinary Bladder Regeneration
Published 2015“…At 4 weeks post-surgery, data demonstrated increased vessel number (~250 vs ~109 vessels/mm<sup>2</sup>) and bladder smooth muscle content (~42% vs ~36%) in Cyr61OX (over-expressing) vs Cyr61KD (knock-down) groups. Muscle content decreased to ~25% at 10 weeks in Cyr61KD groups. Wnt5aOX resulted in high numbers of vessels and muscle content (~206 vessels/mm<sup>2</sup> and ~51%, respectively) at 4 weeks. …”
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8262
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8263
Omentin-1 in diabetes mellitus: A systematic review and meta-analysis
Published 2019“…<div><p>Objective</p><p>Previous studies found inconsistent results on the relationship between diabetes mellitus and concentrations of omentin-1. This study performed a systematic review and meta-analysis to summarize previous findings on this relationship.…”
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8264
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8265
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8266
datasheet1_Pirfenidone Is a Vasodilator: Involvement of KV7 Channels in the Effect on Endothelium-Dependent Vasodilatation in Type-2 Diabetic Mice.pdf
Published 2021“…In mouse coronary arteries, pirfenidone relaxation was inhibited in the presence of a nitric oxide (NO) synthase inhibitor, N<sup>G</sup>-nitro-l-arginine (L-NOARG), a blocker of large-conductance calcium-activated potassium channels (BK<sub>Ca</sub>), iberiotoxin, and a blocker of K<sub>V</sub>7 channels, XE991. …”
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8267
datasheet2_Pirfenidone Is a Vasodilator: Involvement of KV7 Channels in the Effect on Endothelium-Dependent Vasodilatation in Type-2 Diabetic Mice.pdf
Published 2021“…In mouse coronary arteries, pirfenidone relaxation was inhibited in the presence of a nitric oxide (NO) synthase inhibitor, N<sup>G</sup>-nitro-l-arginine (L-NOARG), a blocker of large-conductance calcium-activated potassium channels (BK<sub>Ca</sub>), iberiotoxin, and a blocker of K<sub>V</sub>7 channels, XE991. …”
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8268
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8269
Increased endothelial cell-cell junction size on stiff matrices is diminished after simvastatin treatment.
Published 2016“…<p>Endothelial monolayers are stained for VE-cadherin and cell-cell junction sizes are measured with control and 1 μM simvastatin treatments. (A) Representative images of fluorescently stained VE-cadherin monolayers indicating where junction width measurements were made (black line). …”
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8270
Simvastatin reduces vinculin localization at cell-cell adhesions in endothelial monolayers.
Published 2016“…(C) Vinculin localization per monolayer at cell-cell adhesions, a readout of intercellular junction tension, is quantified and increases with matrix stiffness but is significantly decreased with the statin treatment at higher matrix stiffnesses (n = 3, 70–90 fields of view per condition). …”
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8271
Biofilm formation assays.
Published 2015“…The results demonstrate that PBP1a-deficiency significantly decreased biofilm formation by the deficient mutant (* indicates differences at <i>P</i><0.001 when compared to the wild-type, UA159 under the same conditions). …”
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8272
Canonical and Noncanonical Sites Determine NPT2A Binding Selectivity to NHERF1 PDZ1
Published 2015“…Experimentally introduced mutation in PDZ1 (Glu43Asp and His27Asn) decreased binding to NPT2A. Conversely, introduction of Asp183Glu and Asn167His mutations in PDZ2 promoted the formation of favorable interactions yielding micromolar <i>K</i><sub>D</sub>s. …”
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8273
Tomato HsfA1a plays a critical role in plant drought tolerance by activating <i>ATG</i> genes and inducing autophagy
Published 2018“…On the other hand, <i>HsfA1a</i>-silenced plants increased while its overexpression decreased the levels of insoluble proteins which were highly ubiquitinated under drought stress. …”
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8274
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8275
Functional connectivity and structural analysis of trial spinal cord stimulation responders in failed back surgery syndrome
Published 2020“…There was a negative linear relationship (R<sup>2</sup> = 0.76, p<0.0022) between STM<sub>FCS</sub> index and pain scores. …”
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8276
Proteolysis of CtrA is essential in <i>S</i>. <i>meliloti</i> and requires at least CpdR, RcdA and the last three amino acids of CtrA.
Published 2015“…Pulse-chase experiment of showing decrease over time of radiolabeled CtrA in <i>S</i>. …”
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8277
Epigenome modulated xenobiotic detoxification pathways control DMBA-induced breast cancer in agouti A<sup>vy</sup>/a mice
Published 2019“…Compared to pseudoagouti littermates, a significant decrease in tumour latency with increased tumour burden was observed in slightly mottled and yellow littermates (<i>p</i> ≤ 0.05). …”
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8278
Data_Sheet_1_Alanine Scanning Mutagenesis of the C-Terminal Cytosolic End of Gpm6a Identifies Key Residues Essential for the Formation of Filopodia.pdf
Published 2018“…Expression levels of both truncation mutants were not affected but we observed decrease in the amount of both truncated proteins on cell surface suggesting that the incapacity of the Gpm6a lacking C-terminus to induce filopodium formation is not due to the lower amount of Gpm6a on cell surface. …”
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8279
Ectopic expression of miR-181a enhances lymphoid differentiation in the <i>ETV6/RUNX1</i>-positive cell line and primary ALL blasts.
Published 2015“…In the comparison with the infection control (NC), 181A1-LV-transduced cells derived from patient #1 and #2 both showed a decrease in CD10<sup>High</sup> cells (Patient #1: NC 10.1% / MFI 40.92, 181A1 6.95% / MFI 39.51; Patient #2: NC 40.1% / MFI 424.28, 181A1 29.5% / MFI 444.24) and a relative increase in CD10<sup>Low</sup> cells (Patient #1: NC 87.98% / MFI 165.49, 181A1 91.05% / MFI 156.68; Patient #2: NC 58.1% / MFI 1929.88, 181A1 69% / 1854.4). …”
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8280
Effect of BM pretreatment on CYP3A at mRNA and functional activity level.
Published 2013“…BM treatment decreases the mRNA levels of CYP3A1and CYP3A2 in liver and intestine as assessed by real-time PCR as described in Materials and Methods. …”