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10041
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10042
Nicotinic receptors contribute to synchronous discharges in synaptic blockers aCSF.
Published 2021“…<p>(A) Effect of nonselective nicotinic antagonist mecamylamine on CA3-CA1 synchronous epileptiform discharges induced in synaptic blockers aCSF: (1) single epileptiform discharges; (2) decrease in epileptiform discharges following 50 μM MEC application; (3) epileptiform discharges after mecamylamine wash out. …”
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10043
Measurement of Ammonia in Human Breath with a Liquid-Film Conductivity Sensor
Published 2006“…Measurement of breath NH<sub>3</sub> is of interest in clinical applications as it can be used as a measure of kidney/liver functions as well as halitosis. …”
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10044
Possible mechanisms of the menadione-driven inhibition of the benzo(α)pyrene (BP)-induced AhR-dependent signal transduction pathway.
Published 2016“…<p>Menadione decreases DNA-binding activity of the AhR–ARNT complex thus reducing positive input, and at the same time, activates Oct-1, which inhibits expression of AhR-dependent genes. red triangle—Benzo(α)pyrene, green oval with brown, blue, yellow and red ovals inside—inactive AhR in complex with its protein partners, green oval with a triangle inside—AhR activated by benzo(α)pyrene, pink oval—ARNT, yellow circle—menadione, blue oval—mediator protein, turquoise–light gray oval—Oct-1, NRE: negative regulatory element, XRE: xenobiotic-responsive element, AhR: aryl hydrocarbon receptor, ARNT: aryl hydrocarbon receptor nuclear translocator.…”
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10045
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10046
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10047
Reduced epithelial cell proliferation in Vps35<sup>+/-</sup> cornea.
Published 2017“…<p><b>(A-B)</b> Immunostaining analysis of flat-mounted cornea from Vps35<sup>+/+</sup> and <sup>+/-</sup> mice at indicated ages using anti-Ki67 antibodies. …”
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10048
Abnormality of corneal morphology in Vps35<sup>+/-</sup> cornea.
Published 2017“…<p><b>(A)</b> H & E staining analysis of cross sections of retina and cornea from P90 old Vps35<sup>+/+</sup> and Vps35<sup>+/-</sup> mice. a and a’: retina from Vps35<sup>+/+</sup> and <sup>+/-</sup> mice, respectively; b and b’: cornea from Vps35<sup>+/+</sup> and <sup>+/-</sup> mice, respectively. …”
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10049
Enlarged nuclei sizes and disorganized cytoskeleton in Vps35<sup>+/-</sup> corneal epithelium and endothelium.
Published 2017“…<p><b>(A-B)</b> Immunostaining analysis using anti α-tubulin antibodies or phalloidin (to label F-actin) and Topro3 (to mark nuclei) of flat-mounted corneal endothelium from Vps35<sup>+/+</sup> and <sup>+/-</sup> mice at indicated ages. …”
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10050
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10051
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10052
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10053
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10054
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10055
IL-4 Causes Hyperpermeability of Vascular Endothelial Cells through Wnt5A Signaling
Published 2016“…<div><p>Microvascular leakage due to endothelial barrier dysfunction is a prominent feature of T helper 2 (Th2) cytokine mediated allergic inflammation. …”
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10056
The small molecule rhodomyrtone suppresses TNF-α and IL-17A-induced keratinocyte inflammatory responses: A potential new therapeutic for psoriasis
Published 2018“…This study assessed the potential of rhodomyrtone for curtailing TNF/IL-17A-driven inflammation. Stimulating human skin organ cultures with TNF+IL-17A to model the skin inflammation in psoriasis, we found that rhodomyrtone significantly decreased inflammatory gene expression and the expression and secretion of inflammatory proteins, assessed by qRT-PCR, immunohistochemistry and ELISA assays respectively. …”
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10057
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10058
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10059
In-depth comparison of cell-based methodological approaches to determine drug susceptibility of visceral <i>Leishmania</i> isolates
Published 2019“…Although this assay is widely used, no fully standardized/harmonized protocol is yet available hence resulting in the application of a wide variety of host cells (primary cells and cell lines), different drug exposure times, detection methods and endpoint criteria. …”
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10060