Overexpressed active FOXO3a results in cell proliferation arrest and Akt phosphorylation in drug sensitive breast cancer cell line MCF-7. by Jie Chen (5892)

“…C) SRB assays were performed on these transfected cells, indicating that the ectopic expression of FOXO3a(A3) decreases the cell proliferation rate.</p>…”

Investigation of SB105-A10-related antiviral mechanisms in activated PBMCs infected by HIV-1_IIIb or HIV-1_ada strains. by Isabella Bon (467395)

“…<p>Attachment, pre-attachment and post-attachment assays were carried out as described in panel <b>A</b>, <b>B</b> and <b>C</b> respectively. Significant decreases of HIV-1 gag p24 in the cellular supernatants were detected at day 4 pi, in SB105-A10-treated samples with respect to untreated controls in pre-attachment and attachment assays (panel <b>D</b>). …”

Hsp70 content in CR vs. AL G93A mice. by Barkha P. Patel (366795)

The effect of STOX1A on cell proliferation in the neuroblastoma cell-line SH-SY5Y. by Daan van Abel (214754)

“…<p>(A) The proliferation curve shows significantly decreased cell proliferation for STOX1A siRNA transfected SH-SY5Y cells compared to scrambled controls after 1, 2, and 3 days in culture. …”

Detection of ATP7A by immunofluorescent staining (red) in the coronal brain slices of tx mice. by Ding-Bang Chen (322411)

“…<p>Tx mice were subjected to PA administration for 3 days, 10days and 14days, respectively. (A) Internal pyramidal layer. ATP7A immunoreactivity staining was weak in internal pyramidal layer neurons in the control mice cortex, but increased significantly on the 3rd and the 10th day, then decreased on the 14th day. …”

Pretreatment with rhBCL2A1 protects hind limb skeletal muscle from I/R injury. by Akiko Iwata (229310)

“…Plasma CK levels were significantly decreased in the rhBCL2A1-pretreated mice (*p<0.05). …”

In vitro assay for evaluating the effects of drug treatment on A3 CSC-like clone. by Yu-Ru Lee (381705)

“…The compounds of NSC747854, NSC749232, and NSC749235 decreased d) the cell viability, e) block the sphere formation, and f) inhibit the mRNA expression levels of Parp1 in treated A3 cells. …”

The effect of HPSE miRNA on the <i>in vivo</i> lung metastasis of A375 cells. by Xiaoyan Liu (158152)

“…<p>Cells (2×10⁶) from the parental cells, Neg-miRNA or HPSE-miRNA2 transfected cells were injected into the tail veins of nude mice. (A-B) Xenograft mice were weight once a week for 6 weeks, and photos were taken at the end of the experiment on day 42, as shown in A. …”

Data Sheet 1_Unveiling frailty: comprehensive and sex-specific characterization in prematurely aging PolgA mice.pdf by Dilara Yılmaz (19710658)

“…We demonstrated that frailty became evident in PolgA mice around 40 weeks, validated through body weight loss, reduced walking speed, decreased physical activity, and weaker grip strength. …”

Necrotizing Fasciitis caused by Streptococcus pyogenes: A case report and literature review of disease diagnosis and management by Aziz, Hassan A

“…Background: A 55-year-old male presented to the emergency room at a local hospital complaining of chest discomfort and severe left elbow pain. …”
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The cellular Activating Protein 1 cFos regulates Influenza A virus replication: immunofluorescence and western blot by Antoine Gerodez (21791528)

“…Furthermore, the levels of viral NA mRNA and the expression of late viral proteins NA and M2 decreased upon cFos knockdown. Overall, this study identifies cFos as a proviral factor for IAV, through the modulation of innate immunity and apoptosis during infection, and potentially by supporting the viral transcription.…”

Efficacy of aflibercept on exudative age-related macular degeneration in patients exhibiting complete ranibizumab resistance and tachyphylaxis by Gokcen Gokce (5766071)

“…Eyes were divided into a complete resistance group (n=23 eyes) and tachyphylaxis group (n=21 eyes). …”

Oxidative stress and histopathologic biomarkers of exposure to bisphenol-A in the freshwater fish, Ctenopharyngodon idella by Mehwish Faheem (4827003)

“…<div><p>ABSTRACT Bisphenol-A (BPA) belongs to the family of endocrine disrupting chemicals (EDCs) and it is used in the production of polycarbonate plastic and epoxy resins. …”

The cellular Activating Protein 1 cFos regulates Influenza A virus replication: raw data by Antoine Gerodez (21791528)

“…Furthermore, the levels of viral NA mRNA and the expression of late viral proteins NA and M2 decreased upon cFos knockdown. Overall, this study identifies cFos as a proviral factor for IAV, through the modulation of innate immunity and apoptosis during infection, and potentially by supporting the viral transcription.…”

Glial precursors and mature glial cells were reduced in Her8a knockdown embryos. by Pei-Chen Chung (223912)

“…(J) qPCR analysis showing the levels of <i>slc1a3a</i> and <i>zash1</i> and zrf-1 are significantly decreased in embryos injected with <i>her8a</i> morpholino. * p<0.05.…”

Expression and regulation of NR4A1 by TRH in pituitary thyrotrophs in vivo. by Yasuyo Nakajima (316579)

“…As shown in the right panel, the intensity and number of the TSHβ-immunopositive cells were remarkably decreased in the TRH-deficient pituitary, and at X400, most of the NR4A1 expression was reduced or lost in these cells as seen as black dots (indicated by white arrows). …”

Biochanin A attenuates myocardial ischemia/reperfusion injury through the TLR4/NF-κB/NLRP3 signaling pathway by Yejun Bai (8185029)

“…Biochanin A (BCA) is a main constituent of Trifolium pratense L. …”

Image 10_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.jpeg by Chen Wang (88408)

“…Functional studies demonstrated that RBM15 loss led to increased expression of fumarate hydratase (FH). This led to decreased levels of fumarate, a metabolite known to suppress anti-tumor immune responses. …”

Image 3_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.jpeg by Chen Wang (88408)

“…Functional studies demonstrated that RBM15 loss led to increased expression of fumarate hydratase (FH). This led to decreased levels of fumarate, a metabolite known to suppress anti-tumor immune responses. …”

Image 7_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.tif by Chen Wang (88408)

“…Functional studies demonstrated that RBM15 loss led to increased expression of fumarate hydratase (FH). This led to decreased levels of fumarate, a metabolite known to suppress anti-tumor immune responses. …”