Image 14_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.jpeg by Chen Wang (88408)

“…Functional studies demonstrated that RBM15 loss led to increased expression of fumarate hydratase (FH). This led to decreased levels of fumarate, a metabolite known to suppress anti-tumor immune responses. …”

Table 1_sodA modulates in vitro and in vivo virulence of Yersinia enterocolitica.docx by Yingying Zhang (42910)

“…Inflammatory responses were evaluated through histopathology, immunohistochemistry (NF-κB p65), and qRT-PCR analysis of cytokine expression.</p>Results<p>The ΔsodA mutant exhibited significantly reduced adhesion to and invasion of epithelial cells, impaired survival within macrophages, and decreased colonization in murine ileum and colon tissues. …”

Image 12_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.jpeg by Chen Wang (88408)

“…Functional studies demonstrated that RBM15 loss led to increased expression of fumarate hydratase (FH). This led to decreased levels of fumarate, a metabolite known to suppress anti-tumor immune responses. …”

The role of NF-κB and AhR transcription factors in lead-induced lung toxicity in human lung cancer A549 cells. by Attafi, Ibraheem M

“…Pb treatment induced oxidative stress by a) increasing the formation of reactive oxygen species and b) decreasing GSTA1 mRNA levels. …”
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Supplementary Material for: The Impact of <b><i>CYP24A1</i></b> Polymorphisms on Hypertension Susceptibility by Bao Q. (8272902)

“…<b><i>Results:</i></b> We found that rs56229249 of <i>CYP24A1</i>significantly<i></i>decreased the hypertension risk in homozygote (OR 0.51, 95% CI 0.29–0.91,<i> p</i> = 0.022) and recessive models (OR 0.51, 95% CI 0.29–0.91,<i> p</i> = 0.023). …”

Transwell co-culture of RAW 264.7 macrophages induces metastatic gene expression by A549 cells. by Xiuling Li (130607)

“…<b>D</b> Co-culture of RAW 264.7 macrophages decreased E-cadherin expression by A549 cells. Control A549 and A549-TPα cells were collected after 24 h of culture with or without RAW 264.7 cells as described in A. …”

Image_1_Sema3a as a Novel Therapeutic Option for High Glucose-Suppressed Osteogenic Differentiation in Diabetic Osteopathy.JPEG by Lixia Zhang (187984)

“…</p><p>Results: High glucose significantly inhibited osteogenic differentiation by decreasing the expression of osteogenesis-related makers, sema3a and its receptor of Nrp-1 in a dose-dependent manner in MC3T3. …”

Nuclear proteome profiling in A549 cells after DOX and/or LMB treatment. by Chuanwen Lu (159114)

“…Approximately 1,000 protein spots were detected in nuclear extractions of A549 cells. Spots labeled with red color indicate decreased expression after LMB treatment, while spots labeled with green color indicate increased expression after LMB treatment (left panel). …”

Immunofluorescence of the sst2A receptor in coronal sections through the rat neocortical wall between E14 and P5. by Virginia Le Verche (372926)

“…<p>A–A″′) At E14, the sst2A receptor immunoreactivity is detected in the preplate (PP). …”

validation of A20 target genes in hepatocytes. by Scott M. Damrauer (227334)

“…<b>B)</b> Representative photomicrographs showing decreased p21^waf1 positive cells in liver samples transduced with recombinant adenovirus (rAd.)A20, as compared to control rAd. βgalactosidase (βgal) before resection and increased Ki67 staining 48 hrs after LR. …”

S1.P170 A terpenoids-enriched fraction of Inula viscosa: its chemical composition and anti-cancerous effects against human lung cancer cells by Seglab, Fatiha

“…The anti-cancerous potential of ZNE and F6 was tested in vitro in MDA-MB-231 cells, a TNBC cell line. ZNE and F6 radical scavenging capacity was tested using DPPH assay, and their effects on reactive oxygen species (ROS) generation in vitro in cells by DCFDA staining. …”
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Data_Sheet_1_Monoamino Oxidase a Gene Single-Nucleotide Polymorphisms and Methylation Status and the Risk of Violent Suicide Attempts in Affective Disorder Patients.pdf by Birgit Ludwig (795734)

“…<p>Background: When investigating the neurobiology of suicidal behavior, Monoamino Oxidase A (MAOA) is one of the prime suspects to consider. …”

Image_1_Rapid Eye Movement Sleep Deprivation Combined With Fluoxetine Protects Against Depression-Induced Damage and Apoptosis in Rat Hippocampi via A1 Adenosine Receptor.TIF by Xuan Ju (7353494)

“…</p><p>Results: Depression decreased rat weight. REMSD combined with fluoxetine increased body weight, prompted rat behavior, alleviated depression-induced damage, attenuated apoptosis, and promoted A1 adenosine receptor level in rat hippocampi. …”

Table 1_Eculizumab is efficacious and safe in pediatric patients with various forms of hemolytic uremic syndrome: a retrospective clinical experience of a tertiary center.docx by Naama Lax (20998004)

“…Background<p>Eculizumab, a terminal complement inhibitor, prevents thrombotic microangiopathy (TMA) and multiorgan damage in hemolytic uremic syndrome (HUS). …”

Data_Sheet_1_Monoamino Oxidase A Gene Single-Nucleotide Polymorphisms and Methylation Status and the Risk of Violent Suicide Attempts in Affective Disorder Patients.pdf by Birgit Ludwig (795734)

“…<p>Background: When investigating the neurobiology of suicidal behavior, Monoamino Oxidase A (MAOA) is one of the prime suspects to consider. …”

Analyses of membrane currents elicited by depolarizing voltage ramps in EYFP/Panx1 expressing N2a cells. by Sarah Kurtenbach (475817)

“…<p>N2a cells expressing EYFP or EYFP-tagged mPanx1, drPanx1a or drPanx1b were used for whole-cell patch clamp recordings in the voltage clamp mode 48 h post transient transfection. …”

siRNA-mediated knockdown of VDR induces expression of LVSCC-A1C mRNA and protein. A) Comparison of LVSCC-A1C mRNA levels. by Duygu Gezen-Ak (355264)

“…<b>B) Detection of LVSCC-A1C protein by western blot.</b> Although LVSCC-A1C protein increased in VDR-silenced neurons, vitamin D treatment decreased LVSCC-A1C expression to control levels. …”

Image 1_CHMP4A in hepatocellular carcinoma: exploring its role in tumor progression, immune modulation, and potential link to TIM3 checkpoint.pdf by Kai Sun (140584)

“…Notably, the silencing of CHMP4A markedly decreased the expression levels of the TIM3/LGALS9 immune checkpoint axis in LIHC.…”

Table 1_CHMP4A in hepatocellular carcinoma: exploring its role in tumor progression, immune modulation, and potential link to TIM3 checkpoint.docx by Kai Sun (140584)

“…Notably, the silencing of CHMP4A markedly decreased the expression levels of the TIM3/LGALS9 immune checkpoint axis in LIHC.…”

Table 2_CHMP4A in hepatocellular carcinoma: exploring its role in tumor progression, immune modulation, and potential link to TIM3 checkpoint.docx by Kai Sun (140584)

“…Notably, the silencing of CHMP4A markedly decreased the expression levels of the TIM3/LGALS9 immune checkpoint axis in LIHC.…”