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Assessing the effects of a vascular disrupting agent.
Published 2012“…The images demonstrate a large increase in the necrotic regions following DMXAA treatment. …”
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11325
Dose-response effects of TGF-beta on TMEM16A, CFTR, e-cadherin, and vimentin in T84 cells.
Published 2014“…<p>T84 cells were treated with TGF-beta (vehicle control, 0.1, 1.0, and10 ng/ml) for 48 h, followed by Ussing chamber and immunoblot as described in Methods. (<b>A and B</b>) CaCC (*<i>P<</i>0.003, **P<0.01) and CFTR (*<i>P<</i>0.0001) currents were reduced by TGF-beta treatment at every dose used. …”
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11326
Dose-response effects of TGF-beta on TMEM16A, CFTR, e-cadherin, and vimentin in HAECs.
Published 2014“…<p>HAECs were treated with TGF-beta (vehicle control, 0.1, 1.0, and10 ng/ml) for 48 h, followed by Using chamber and immunoblot as described in Methods. (<b>A and B</b>) CaCC (*<i>P<</i>0.0016) and CFTR (*<i>P<</i>0.0001) currents were reduced by TGF-beta treatment at every dose used. …”
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11327
<i>In silico</i> Analysis of Conformational Changes Induced by Mutation of Aromatic Binding Residues: Consequences for Drug Binding in the hERG K+ Channel
Published 2011“…Nevertheless, some drugs are only weakly affected by mutation Y652A. In this study we utilize molecular dynamics simulations and docking studies to analyze the different effects of mutation Y652A on a selected number of hERG blockers. …”
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11328
Image_1_Perinatal Exposure of Bisphenol A Differently Affects Dendritic Spines of Male and Female Grown-Up Adult Hippocampal Neurons.tif
Published 2021“…Concerning the BPA effect on the morphology of spines, the large-head spine was significantly changed with its significant decrease in males and moderate change in females.…”
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11329
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11330
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11331
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11332
<i>NbDRP2–1/2</i> is required for FLS2 internalization.
Published 2015“…<p>(A) Confocal imaging in <i>N</i>. <i>benthamiana</i> pavement cells reveals that decreased <i>NbDRP2–1/2</i> expression leads to a significant reduction of subcellular distribution of FLS2-GFP in endosomes (green dots) after flg22 elicitation (100 μM). …”
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11333
Polygenic Analysis of Late-Onset Alzheimer’s Disease from Mainland China
Published 2015“…<div><p>Recently, a number of single nucleotide polymorphisms (SNPs) were identified to be associated with late-onset Alzheimer disease (LOAD) through genome-wide association study data. …”
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11334
Selective C−H Activation of Haloalkanes using a Rhodiumtrispyrazolylborate Complex
Published 2009“…By comparing the kinetic stabilities of a series of 1-chloroalkane activation products (C<sub>1</sub>−C<sub>5</sub>), it was found that the chlorine substituent dramatically decreases reductive elimination rates as the substitution is closer to the metal center. …”
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11335
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11336
DataSheet_1_LINC00460 Is a Dual Biomarker That Acts as a Predictor for Increased Prognosis in Basal-Like Breast Cancer and Potentially Regulates Immunogenic and Differentiation-Rel...
Published 2021“…Finally, LINC00460:WNT7A ratio constitutes a composite marker for decreased OS and DMFS in Basal-like BRCA, and can predict anthracycline therapy response in ER-BRCA patients. …”
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11337
image1_Astragaloside IV Inhibits Galactose-Deficient IgA1 Secretion via miR-98-5p in Pediatric IgA Nephropathy.tif
Published 2021“…The overexpression of miR-98-5p in DAKIKI cells decreased both the mRNA and protein levels of C1GALT1 and increased the levels of Gd-IgA1 levels; these effects were reversed by co-transfection with the C1GALT1 plasmid, and vice versa. …”
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11338
datasheet1_Astragaloside IV Inhibits Galactose-Deficient IgA1 Secretion via miR-98-5p in Pediatric IgA Nephropathy.zip
Published 2021“…The overexpression of miR-98-5p in DAKIKI cells decreased both the mRNA and protein levels of C1GALT1 and increased the levels of Gd-IgA1 levels; these effects were reversed by co-transfection with the C1GALT1 plasmid, and vice versa. …”
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11339
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Data_Sheet_1_TGFβ Signaling Increases Net Acid Extrusion, Proliferation and Invasion in Panc-1 Pancreatic Cancer Cells: SMAD4 Dependence and Link to Merlin/NF2 Signaling.PDF
Published 2020“…<p>Pancreatic ductal adenocarcinoma (PDAC) is a major cause of cancer-related death, with a 5-year survival of <10% and severely limited treatment options. …”