Table 2_Clinical features and genetic analysis of acrodermatitis enteropathica in an ethnic minority infant from Western China: a case report and literature review.xlsx by Tuerhongjiang Axirejiang (22346272)

“…Her serum zinc level significantly decreased (0.19 mg/L). Whole-exome sequencing revealed a homozygous c.197G > T(p. …”

Image 1_A novel dual DYRK1A/B inhibitor for the treatment of type 1 diabetes.tiff by Šarūnas Tumas (22419055)

“…</p>Results<p>Pharmacokinetic analysis confirmed the oral bioavailability of FX8474, and treatment was associated with improved fasted glucose levels and glucose tolerance after a 7-day treatment. Immunophenotyping indicated that FX8474 treatment increases CD4+ memory T cell populations while decreasing CD4+ effector cells, as well as restores CD8+ T cell phenotypes to levels observed in healthy mice.…”

Table_1_LaeA Controls Virulence and Secondary Metabolism in Apple Canker Pathogen Valsa mali.docx by Yaqiong Feng (9604034)

“…Toxicity tests proved that toxicity of secondary metabolites (SMs) produced by VmLaeA deletion mutant (ΔVmlaeA) was markedly decreased in comparison with wild-type (WT). …”

Reciprocal Regulation of Annexin A2 and EGFR with Her-2 in Her-2 Negative and Herceptin-Resistant Breast Cancer by Praveenkumar K. Shetty (139121)

“…This effect was consistent in Herceptin resistant JIMT-1 cells as well as in Her-2 negative breast cancer. The siRNA mediated AnxA2 downregulation leads to increased apoptosis, decreased cell viability and migration. …”

Supplementary file 1_A novel dual DYRK1A/B inhibitor for the treatment of type 1 diabetes.docx by Šarūnas Tumas (22419055)

“…</p>Results<p>Pharmacokinetic analysis confirmed the oral bioavailability of FX8474, and treatment was associated with improved fasted glucose levels and glucose tolerance after a 7-day treatment. Immunophenotyping indicated that FX8474 treatment increases CD4+ memory T cell populations while decreasing CD4+ effector cells, as well as restores CD8+ T cell phenotypes to levels observed in healthy mice.…”

Table 1_Clinical features and genetic analysis of acrodermatitis enteropathica in an ethnic minority infant from Western China: a case report and literature review.xlsx by Tuerhongjiang Axirejiang (22346272)

“…Her serum zinc level significantly decreased (0.19 mg/L). Whole-exome sequencing revealed a homozygous c.197G > T(p. …”

Image_3_LaeA Controls Virulence and Secondary Metabolism in Apple Canker Pathogen Valsa mali.TIF by Yaqiong Feng (9604034)

“…Toxicity tests proved that toxicity of secondary metabolites (SMs) produced by VmLaeA deletion mutant (ΔVmlaeA) was markedly decreased in comparison with wild-type (WT). …”

Table 1_Gamma knife radiosurgery for cerebral cavernous malformations: biologically effective dose predicts therapeutic outcomes.docx by Xiaoman Shi (12587770)

“…Fowler, has been widely discussed in radiobiology but not evaluated in CCMs.</p>Methods<p>A retrospective cohort study was conducted on 107 patients with 123 CCMs treated by GKRS at West China Hospital between June 2020 and December 2022. …”

Data_Sheet_2_LaeA Controls Virulence and Secondary Metabolism in Apple Canker Pathogen Valsa mali.docx by Yaqiong Feng (9604034)

“…Toxicity tests proved that toxicity of secondary metabolites (SMs) produced by VmLaeA deletion mutant (ΔVmlaeA) was markedly decreased in comparison with wild-type (WT). …”

Image_2_LaeA Controls Virulence and Secondary Metabolism in Apple Canker Pathogen Valsa mali.TIF by Yaqiong Feng (9604034)

“…Toxicity tests proved that toxicity of secondary metabolites (SMs) produced by VmLaeA deletion mutant (ΔVmlaeA) was markedly decreased in comparison with wild-type (WT). …”

Data_Sheet_1_LaeA Controls Virulence and Secondary Metabolism in Apple Canker Pathogen Valsa mali.xlsx by Yaqiong Feng (9604034)

“…Toxicity tests proved that toxicity of secondary metabolites (SMs) produced by VmLaeA deletion mutant (ΔVmlaeA) was markedly decreased in comparison with wild-type (WT). …”

Image_6_LaeA Controls Virulence and Secondary Metabolism in Apple Canker Pathogen Valsa mali.TIF by Yaqiong Feng (9604034)

“…Toxicity tests proved that toxicity of secondary metabolites (SMs) produced by VmLaeA deletion mutant (ΔVmlaeA) was markedly decreased in comparison with wild-type (WT). …”

Image 2_A novel dual DYRK1A/B inhibitor for the treatment of type 1 diabetes.jpeg by Šarūnas Tumas (22419055)

“…</p>Results<p>Pharmacokinetic analysis confirmed the oral bioavailability of FX8474, and treatment was associated with improved fasted glucose levels and glucose tolerance after a 7-day treatment. Immunophenotyping indicated that FX8474 treatment increases CD4+ memory T cell populations while decreasing CD4+ effector cells, as well as restores CD8+ T cell phenotypes to levels observed in healthy mice.…”

Image 4_A novel dual DYRK1A/B inhibitor for the treatment of type 1 diabetes.jpeg by Šarūnas Tumas (22419055)

“…</p>Results<p>Pharmacokinetic analysis confirmed the oral bioavailability of FX8474, and treatment was associated with improved fasted glucose levels and glucose tolerance after a 7-day treatment. Immunophenotyping indicated that FX8474 treatment increases CD4+ memory T cell populations while decreasing CD4+ effector cells, as well as restores CD8+ T cell phenotypes to levels observed in healthy mice.…”

Underexpression of miR-34a in Hepatocellular Carcinoma and Its Contribution towards Enhancement of Proliferating Inhibitory Effects of Agents Targeting c-MET by Yiwu Dang (401417)

“…In the current study, we have investigated the clinical significance and the <i>in vitro</i> contribution of miR-34a on biological functions of human HCCs. miR-34a expression in eighty-three cases of HCC formalin-fixed paraffin-embedded (FFPE) tissues decreased significantly compared to that in the adjacent liver tissues (<i>P</i><0.01), as detected by real-time quantitative RT-PCR (RT-qPCR). miR-34a expression in the groups of TNM stage I and II, without metastasis and without portal vein tumor embolus, was significantly higher than that of their corresponding groups (<i>P</i><0.05). …”

Data_Sheet_1_Antivirulence activities of retinoic acids against Staphylococcus aureus.docx by Inji Park (16975800)

“…Of the three retinoic acids examined, 13-cis-retinoic acid at 10 μg/mL significantly decreased S. aureus biofilm formation without affecting its planktonic cell growth (MIC >400 μg/mL) and also inhibited biofilm formation by Staphylococcus epidermidis (MIC >400 μg/mL), but less affected biofilm formation by a uropathogenic Escherichia coli strain, a Vibrio strain, or a fungal Candida strain. …”

Table_1_Comparative Transcriptional Analysis of Lactobacillus plantarum and Its ccpA-Knockout Mutant Under Galactooligosaccharides and Glucose Conditions.XLSX by Chen Chen (6544)

“…In total, 489 genes (16%) were differentially transcribed in the wild-type L. plantarum grown on glucose and GOS and the value is decreased to 7% due to the loss of ccpA. Only 6% genes were differentially expressed when the wild-type and the ccpA mutant were compared on GOS. …”

Image_1_LaeA Controls Virulence and Secondary Metabolism in Apple Canker Pathogen Valsa mali.TIF by Yaqiong Feng (9604034)

“…Toxicity tests proved that toxicity of secondary metabolites (SMs) produced by VmLaeA deletion mutant (ΔVmlaeA) was markedly decreased in comparison with wild-type (WT). …”

Data Sheet 1_Regulation of SLC7A11 by LncRNA GPRC5D-AS1 mediates ferroptosis in skeletal muscle: Mechanistic exploration of sarcopenia.pdf by Wei Gong (112494)

“…In the sarcopenia group, both GPRC5D-AS1 and SLC7A11 expression levels decreased significantly, along with SLC7A11 protein translation. …”

Data_Sheet_3_Comparative Transcriptional Analysis of Lactobacillus plantarum and Its ccpA-Knockout Mutant Under Galactooligosaccharides and Glucose Conditions.PDF by Chen Chen (6544)

“…In total, 489 genes (16%) were differentially transcribed in the wild-type L. plantarum grown on glucose and GOS and the value is decreased to 7% due to the loss of ccpA. Only 6% genes were differentially expressed when the wild-type and the ccpA mutant were compared on GOS. …”