Data_Sheet_1_The microbiota and metabolome dynamics and their interactions modulate solid-state fermentation process and enhance clean recycling of brewers’ spent grain.docx by Yueqin Xie (6282224)

“…Microbiologically, during the SSF, the group treated with MS inoculation exhibited an increase in the relative abundance of Leuconostoc (0.58%∼6.60%), Weissella (6.22%∼15.42%), Enterococcus (3.15%∼9.08%), Bacillus (17.63%∼31.29%), Lactobacillus (12.89%∼8.29%), Pseudoalteromonas (12.87%∼16.29%), and a decrease in the relative abundance of Acinetobacter (0.79%∼0.02%) and Enterobacteriaceae (0.78%∼0.24%). …”

Image_1_Differential effects of allopregnanolone and diazepam on social behavior through modulation of neural oscillation dynamics in basolateral amygdala and medial prefrontal cor... by Yosuke Yawata (5142431)

“…One hypothesis for the mechanism of depression involves a decrease in neuroactive steroids such as allopregnanolone, an endogenous positive allosteric modulator of the γ-aminobutyric acid–gated chloride channel (GABA_A) receptor. …”

Cobratoxin Alleviates Cancer-Induced Bone Pain in Rats via Inhibiting CaMKII Signaling Pathway after Acting on M4 Muscarinic Cholinergic Receptors by Longsheng Xu (4519405)

“…Cancer-induced bone pain (CIBP) is a common pain in clinics, which can reduce the quality of life and increase the mortality of patients, but the treatment of CIBP is limited. …”

Table_3_Dupilumab effectively and rapidly treats bullous pemphigoid by inhibiting the activities of multiple cell types.xlsx by Tianmeng Yan (16682754)

“…</p>Objective<p>We evaluated the efficiency and safety of dupilumab on BP treatment and explored a mode of drug action in depth.</p>Methods and results<p>A multicenter retrospective cohort included 20 BP patients who received dupilumab with or without systemic corticosteroid in dupilumab group, and 20 matched BP patients who received corticosteroid alone in conventional group. …”

Image_5_The Composition and Cellular Sources of CSPGs in the Glial Scar After Spinal Cord Injury in the Lamprey.TIF by Guixin Zhang (795314)

“…Expression levels are relatively high in embryonic and early larval stages, gradually decrease, and are upregulated again in adults. Reductions of lecticans B and D are greater than those of A and C. …”

Table_1_Elevation of Serum Cytokine Profiles and Liver Metabolomic Normalization in Early Convalescence of COVID-19 Patients.DOCX by Yan Lou (1692556)

“…<p>Coronavirus disease 2019 (COVID-19) has become a global public health concern. We aimed to study the cytokine profile during the convalescent phase and its association with liver functions. …”

Image_1_Bile Acids Elevated in Chronic Periaortitis Could Activate Farnesoid-X-Receptor to Suppress IL-6 Production by Macrophages.jpeg by Shan Cao (5077988)

“…Dual-luciferase report assay and ChIP assay demonstrated that upon activation, FXR could directly bind to the promoter site of IL-6, leading to the decreased expression of IL-6. Thus, bile acids, especially CDCA, may operate to damp inflammation via FXR-mediated downregulation of IL-6 in mononuclear cells and provide a protective mechanism for CP patients.…”

Table1_Magnesium-Assisted Cisplatin Inhibits Bladder Cancer Cell Survival by Modulating Wnt/β-Catenin Signaling Pathway.PDF by Tianye Li (9759056)

“…Most importantly, a marked decrease in nuclear β-catenin was observed in cells that received cisplatin treatment. …”

Table_3_Soil Salinity Controls Relative Abundance of Specific Bacterial Groups Involved in the Decomposition of Maize Plant Residues.pdf by Arit S. De León-Lorenzana (5214002)

“…Application of the NDF generally had a similar effect on the bacterial community structure as when maize plants were applied. …”

Isotopic and Geochemical Tracers for U(VI) Reduction and U Mobility at an in Situ Recovery U Mine by Anirban Basu (102199)

“…Postmining natural attenuation of residual U­(VI) at ISR mines is a potential remediation strategy. Detection and monitoring of naturally occurring reducing subsurface environments are important for successful implementation of this remediation scheme. …”

Table1.docx by Yan Liu (25061)

“…However, few studies stem from the perspective of whole transcriptome change in a fish brain and its response to long-term hypersaline stress. …”

Datasheet1_TIMP3 induces gene expression partly through PI3K and their association with vascularization and heart rate.pdf by Zi-Meng Xia (14847547)

“…Background<p>Tissue inhibitor of metalloproteinase 3 (TIMP3) was recently demonstrated capable to regulate some gene expression in a myocardial infarction model. Here we aim to explore the gene expression profile in TIMP3-treated cardiomyocytes and related potential cardiovascular functions.…”

Presentation_1_Perivascular adipose tissue promotes vascular dysfunction in murine lupus.pptx by Hong Shi (177669)

“…In addition, expression of UCP1, a brown/beige adipose marker, was dramatically decreased, while CD45-positive leukocyte infiltration was increased, in PVAT from lupus mice. …”

Supplementary material for “Genetic insights into causal effects of serum lipids and lipid-lowering drug target genes on autoimmune thyroid disease” by Qinnan Zhang (18874897)

“…In cross-ancestry analysis, we found that CETP had a potential protective effect in GD (OR=0.43, 95%CI=0.21-0.86; P=0.018). …”

Boron doped silver-copper alloy nanoparticle targeting intracellular <i>S</i>. <i>aureus</i> in bone cells by Tahir Abdulrehman (8697696)

“…The ACB-OBAb nanoparticles showed a 1.32 log reduction of intracellular <i>S</i>. …”

Motor function impairment in the three stroke models. by Oliver Schmitt (159300)

“…Different from the sMCAO, the dMCAO and ICH had no significant change in the temporal parameter of stride length, The paw intensity and max area of affected limbs of ICH rats had a similar significant decrease with sMCAO. The paw intensity and max area were reduced at the paws after dMCAO, but only had significant difference in the paw intensity of the affected forepaw (RF). …”

Image_5_Integration analysis identifies the role of metallothionein in the progression from hepatic steatosis to steatohepatitis.tif by Xiaoya Li (2022250)

“…Background<p>Non-alcoholic fatty liver disease (NAFLD), a metabolic disorder that develops from non-alcoholic fatty liver (NAFL) to non-alcoholic steatohepatitis (NASH), has become an epidemic of chronic liver dysfunction worldwide. …”

DataSheet_2_(-)-Sativan Inhibits Tumor Development and Regulates miR-200c/PD-L1 in Triple Negative Breast Cancer Cells.pdf by Fu Peng (1426402)

“…Hence, it is worthwhile to find an effective approach in inhibiting EMT-activated TNBC cells. (-)-Sativan (SA) is a naturally isolated isoflavane and could be isolated from Spatholobus suberectus, a common traditional Chinese medicine used for breast cancer treatment. …”

Table_2_Effects of Dietary Ginsenoside Rg1 Supplementation on Growth Performance, Gut Health, and Serum Immunity in Broiler Chickens.DOCX by Zehe Song (3723604)

“…Our results showed that dietary supplementation of 300 mg/kg ginsenoside Rg1 significantly improved the growth performance for broilers, particularly at the late stage, including an increase in final body weight and decrease of feed conversion ratio (P < 0.05). Additionally, the integrity of intestinal morphology (Villus height, Crypt depth, and Villus height/Crypt depth) and tight junction (ZO-1 and Occludin), and the secretion of sIgA in the intestine were enhanced by the supplementation of Rg1 in chicken diet (P < 0.05). …”

Image_4_Profiling the Urinary Microbiota in Male Patients With Bladder Cancer in China.TIF by Peng Wu (210686)

“…The link between chronic inflammation, microbiome and solid tumors has been established for various neoplastic diseases. However, a detailed and comprehensive analysis of urinary microenvironment of bladder cancer has not been yet reported. …”