Interactions between αv-Integrin and HER2 and Their Role in the Invasive Phenotype of Breast Cancer Cells In Vitro and in Rat Brain by Sangeet Lal (776570)

“…Knockdown of αv-integrin altered HER2 localization from its normal membrane position to a predominantly lysosomal localization. When αv-integrin expression was decreased by 69–93% in HER2-expressing cells, cellular motility was significantly reduced. …”

Information on miR-335-3p mimic and inhibitor. by Dong-Hee Han (140305)

“…When the miR-335-3p mimic was transfected in TGF-β1-treated respiratory epithelial cells, THBS1 and fibrosis markers were downregulated, while the introduction of miR-335-3p inhibitor exhibited a reverse phenomenon. Our findings demonstrated that TGF-β1 exposure to respiratory epithelial cells led to a decrease in miR-335-3p expression, resulting in the upregulation of THBS1 and ultimately exacerbating fibrosis. …”

Table1_Association of mitochondrial haplogroup H with reduced risk of type 2 Diabetes among Gulf Region Arabs.xlsx by Mohammed Dashti (4849747)

“…For example, haplogroups F, D, M9, and N9a have been linked to an elevated risk of T2D across various populations. …”

Table1_Aquaporin-8 transports hydrogen peroxide to regulate granulosa cell autophagy.XLSX by Binbin Huang (2863526)

“…Immunofluorescence staining and transmission electron microscopic examination indicated that the number of autophagosomes in the granulosa cells of Aqp8^−/− mice decreased. Using a follicular granulosa cell autophagy model, namely a follicular atresia model, we verified that the concentration of H₂O₂ significantly increased during the autophagy of granulosa cells, consistent with the Aqp8 mRNA level. …”

Data_Sheet_1_The Spectrum of SPTA1-Associated Hereditary Spherocytosis.PDF by Satheesh Chonat (5980190)

“…Patients with HS have defects in the genes coding for ankyrin (ANK1), band 3 (SLC4A1), protein 4.2 (EPB42), and α (SPTA1) or β-spectrin (SPTB). …”

Image_1_Focal non-invasive deep-brain stimulation with temporal interference for the suppression of epileptic biomarkers.JPEG by Emma Acerbo (10933287)

“…</p>Results<p>This non-invasive DBS increases physiological ripples, and decreases the number of FRs and IEDs in a mouse model of epilepsy. …”

DataSheet1_The Involvement of TRIB3 and FABP1 and Their Potential Functions in the Dynamic Process of Gastric Cancer.XLSX by Songyi Liu (11589508)

“…Hp infection was significantly associated with the decreased expression of TRIB3 and FABP1. In addition, the diagnostic efficiency of the combination of these two indicators to diagnose EGC was higher than that of a single indicator. …”

Abnormal Hindlimb Posture, Reduced Grip Strength, and Muscle Wasting in <i>Hottip</i>^{<i>−⁄−</i>} Mice. by Ka-Man Venus Lai (729684)

“…Data are means +/−SEM, n = 6 mice for each group. A significant decrease in muscle weight was observed only in the GA of <i>Hottip</i>^{<i>−⁄−</i>} animal in both males and females (male data not shown). …”

Table_1_Quantitative Profiling of Oxylipins in Acute Experimental Intracerebral Hemorrhage.DOCX by Jun-Jie Yuan (8552463)

“…Among these, Cyp4f18, Cyp1b1, Cyp2d3, Cyp2e1, Cyp1a1, ALOX5AP, and PLA2g4a were found up-regulated and Cyp26b1 was found to decrease in ICH. …”

Table_4_Gut Microbiota Composition and Metabolic Potential of Long-Living People in China.pdf by Siyuan Zhang (2044930)

“…In the taxonomic composition, it was shown that long-living people contained more short-chain fatty acid (SCFA)-producing bacteria and a decrease in certain pathogenic bacteria. Functional analysis also showed that the long-living people were enriched in metabolism metabolites methanol, trimethylamine (TMA), and CO₂ to methane, and lysine biosynthesis, but the genes related to riboflavin (vitamin B2) metabolism and tryptophan biosynthesis were significantly reduced in long-living individuals. …”

β-Catenin Loss- or Gain-of-Function during the Initial Repair Phase Represses Fracture Healing by Yan Chen (4308)

“…</p> <p>(L) Western blot of SOX9 at 1 wk and RUNX2 at 3 wk following fracture shows a decrease of both markers in the Cre-null and Cre-stab mice.…”

Table_2_Subclinical doses of dietary fumonisins and deoxynivalenol cause cecal microbiota dysbiosis in broiler chickens challenged with Clostridium perfringens.docx by Revathi Shanmugasundaram (176342)

“…At the genus level, FUM + DON exposure decreased (P < 0.05) Acinetobacter and Pseudomonas abundance and had a tendency (P = 0.08) to decrease Thermincola abundance compared to the control group. …”

Administration of anatabine inhibits pro-inflammatory cytokines but does not affect the titer of circulating anti-MOG antibodies. by Daniel Paris (286121)

“…A significant decrease in TNF-α (Mann-Whitney U = 22, Z = −3.622, P<0.001), IL-1β (Mann-Whitney U = 9, Z = −4.19, P<0.001) and IL-17 (Mann-Whitney U = 55, Z = −1.976, P<0.05) was observed in the spleen of anatabine treated EAE mice compared to placebo EAE mice. (* P<0.05 for EAE placebo mice vs control non-immunized mice; ¤ P<0.05 for EAE placebo mice vs EAE anatabine treated mice).…”

Impact of Growth Hormone (GH) Deficiency and GH Replacement upon Thymus Function in Adult Patients by Gabriel Morrhaye (264094)

“…There was also a decrease in intrathymic T cell proliferation as indicated by the reduced sj/β TREC ratio (p<0.01). …”

Table_2_Dynamics of circulating follicular helper T cell subsets and follicular regulatory T cells in rheumatoid arthritis patients according to HLA-DRB1 locus.docx by Paola V. Ferrero (5804372)

“…Interestingly, when analyzing paired samples, the frequency of Tfh cells was reduced in synovial fluid compared to peripheral blood, while Tfr cells levels were similar in both biological fluids. After treatment, a decrease in the CCR7^loPD1^hi Tfh subset and an increase in the frequency of Tfr cells was observed in blood. …”

Effect of mitomycin C (MMC) on Pgp-EGFP functionality studied with the Rho123 uptake assay. by Andreas Noack (519906)

“…As shown in the inset, this was correlated with a decrease of Pgp in the DRM fraction and an increase of Pgp in the detergent soluble fraction. …”

Image_2_The Increased Risk of Thyroid Cancer-Specific Mortality With Tumor Size in Stage IVB Patients.PNG by Junyi Zhang (290426)

“…Kaplan-Meier curves showed the increased tumor size was associated with a statistically significant decrease in TC-specific survival (P < 0.001). …”

Image1_Dihydroartemisinin Alleviates Imiquimod-Induced Psoriasis-like Skin Lesion in Mice Involving Modulation of IL-23/Th17 Axis.tif by Jiang-Min Liu (11275800)

“…DHA restored the expression of IFN-γ, IL-17A, and IL-23 in skins, as well as a decrease of cytokines and chemokines in skin supernatant. …”

DataSheet_4_Thymoproteasome-Expressing Mesenchymal Stromal Cells Confer Protective Anti-Tumor Immunity via Cross-Priming of Endogenous Dendritic Cells.pdf by Jean-Pierre Bikorimana (8553237)

“…Phenotypic and molecular characterization of MSC-TPr revealed a substantial decrease in MHCI (H2-K^b and H2-D^d) expression along with elevated secretion of various chemokines (CCL2, CCL9, CXCL1, LIX, and CX3CL1). …”

Table_1_Subclinical doses of dietary fumonisins and deoxynivalenol cause cecal microbiota dysbiosis in broiler chickens challenged with Clostridium perfringens.docx by Revathi Shanmugasundaram (176342)

“…At the genus level, FUM + DON exposure decreased (P < 0.05) Acinetobacter and Pseudomonas abundance and had a tendency (P = 0.08) to decrease Thermincola abundance compared to the control group. …”