Triggered radiosensitizer delivery using thermosensitive liposomes and hyperthermia improves efficacy of radiotherapy: An <i>in vitro</i> proof of concept study by Helena C. Besse (5759366)

“…<div><p>Introduction</p><p>To increase the efficacy of chemoradiation and decrease its toxicity in normal tissue, a new concept is proposed, local radiosensitizer delivery, which combines triggered release of a radiosensitizer from thermosensitive liposomes with local hyperthermia and radiotherapy. …”

Table1_Effects of shading on morphology, photosynthesis characteristics, and yield of different shade-tolerant peanut varieties at the flowering stage.docx by Jing Wang (6206297)

“…Shade stress led to decreased dry-matter accumulation, reduced weight of 100 fruits and kernels, and a significant decline in yield in the shade-sensitive cultivars. …”

Luteolin and Quercetin Affect the Cholesterol Absorption Mediated by Epithelial Cholesterol Transporter Niemann–Pick C1-Like 1 in Caco-2 Cells and Rats by Mari Nekohashi (568140)

“…Epidemiological studies demonstrated that consumption of polyphenols correlates with a decreased risk for atherosclerosis due to their antioxidant effect. …”

Presentation_1_Alteration of gut microbiota after heat acclimation may reduce organ damage by regulating immune factors during heat stress.PDF by Shanshou Liu (14587686)

“…The composition, metabolism, and pathogenicity of gut microbes changed significantly, with a decreased proportion of potentially pathogenic bacteria (Escherichia-Shigella and Lactococcus) and increased probiotics (Dorea, Blautia, and Lactobacillus) in the HA group. …”

DataSheet_1_Regulatory T cell enhancement in adults with cystic fibrosis receiving Elexacaftor/Tezacaftor/Ivacaftor therapy.docx by Dirk Westhölter (14632553)

“…Cytokine measurements showed a significant decrease in interleukin-6 levels during treatment with elexacaftor/tezacaftor/ivacaftor (–50.2%, p<0.001).…”

Image3_Disordered Gut Microbiota in Colorectal Tumor-Bearing Mice Altered Serum Metabolome Related to Fufangchangtai.TIF by Mengmeng Cai (12480588)

“…</p><p>Results: The tumor volume of mice showed no significant decrease after FFCT intervention. The levels of CD4⁺ and CD8⁺T lymphocytes showed a significant increase under the intervention of FFCT. …”

Data_Sheet_1_Climate-Smart Cocoa in Ghana: How Ecological Modernisation Discourse Risks Side-Lining Cocoa Smallholders.PDF by Felix Nasser (8902994)

“…Through semi-structured interviews and focus group discussions with key stakeholders in Ghana's cocoa sector, we find overwhelming consensus for an ecological modernisation discourse with the promise of a “triple win” narrative that simultaneously stops deforestation, supports climate mitigation and adaptation, and increases smallholder livelihoods. …”

Data_Sheet_1_Channelrhodopsin Excitation Contracts Brain Pericytes and Reduces Blood Flow in the Aging Mouse Brain in vivo.docx by Amy R. Nelson (8778641)

“…French physiologist Rouget was the first to describe pericytes in 1873 as regularly arranged longitudinal amoeboid cells on capillaries that have a muscular coat, implying that these are contractile cells that regulate blood flow. …”

Minimally Invasive Cardiac Surgery versus Sternotomy - Pain Investigation by Juliana Fernandes Silva (7292450)

“…In addition, patients subjected to MI procedure had a significant decrease in pain intensity from the third to the seventh PO days (p = 0.001). …”

Image_1_Anticancer Effects of Wild Mountain Mentha longifolia Extract in Adrenocortical Tumor Cell Models.jpeg by Felicia Patti (8429184)

“…Recently, its antiproliferative role has been suggested in a small number of tumor cell models, but no data are available on adrenocortical carcinoma, a malignancy with a survival rate at 5 years of 20%–30% which frequently metastasize. …”

Image_3_Anticancer Effects of Wild Mountain Mentha longifolia Extract in Adrenocortical Tumor Cell Models.jpeg by Felicia Patti (8429184)

“…Recently, its antiproliferative role has been suggested in a small number of tumor cell models, but no data are available on adrenocortical carcinoma, a malignancy with a survival rate at 5 years of 20%–30% which frequently metastasize. …”

Data_Sheet_1_Omega-3 long chain highly unsaturated fatty acid content in tissue correlates with escape response efficiency in golden gray mullet.pdf by Marie Vagner (748146)

“…Fish were fed either a standard n-3 HUFA diet or an n-3 HUFA-deficient diet for 2 months. …”

Table_1_Protective efficacy of statins in patients with Klebsiella pneumoniae bloodstream infection.docx by Qian Xu (119888)

“…Background<p>Patients with bloodstream infection of Klebsiella pneumoniae (BSI-KP) have a high risk of death and septic shock. This study aims to identify the risk factors for mortality and severity in patients of BSI-KP.…”

Data_Sheet_1_Effect of the COVID-19 pandemic and international travel ban on elephant tourist camp management in northern Thailand.docx by Jarawee Supanta (14207471)

“…Results revealed significant changes in camp structure, elephant work activities and general care. Staff layoffs led to a decrease in the ratio of mahouts to elephants from 1:1 to 1:2. …”

Image_1_Altered Transcription Factor Expression Responses to Exercise in Insulin Resistance.PDF by Rocio Zapata-Bustos (10533320)

“…Q-rt-PCR analysis of RNA and immunoblot analysis from pre- and post-exercise muscle biopsies revealed several transcription and growth factors that had altered responses to exercise in insulin resistant participants. A significant increase (EGR3 and CTGF) and decrease (RELA and ATF2) in the mRNA expression of transcription and growth factors was found after exercise in the lean group, but not in the obese participants.…”

Image_4_Anticancer Effects of Wild Mountain Mentha longifolia Extract in Adrenocortical Tumor Cell Models.jpeg by Felicia Patti (8429184)

“…Recently, its antiproliferative role has been suggested in a small number of tumor cell models, but no data are available on adrenocortical carcinoma, a malignancy with a survival rate at 5 years of 20%–30% which frequently metastasize. …”

Fig 4 - by Sonia Borao (18764889)

“…Line plots represent the average splicing efficiency in <i>Δsaf5</i> (red line) and wild type (blue line) strains. Genes with a decrease of 50% in splicing efficiency in <i>Δsaf5</i> compared with wild type strain in the first (left panel), second (middle panel) and third (right panel) intron are represented.…”

Data Sheet 2_Deep crustal composition and Late Paleozoic geotectonic evolution in West Junggar, China.pdf by Shenglin Xu (12076840)

“…In the Early Permian period (294–272 Ma), there was an intracontinental evolution stage and a decrease in the participation of juvenile material. …”

Image_3_MaMYB4, an R2R3-MYB Repressor Transcription Factor, Negatively Regulates the Biosynthesis of Anthocyanin in Banana.JPEG by Gui-Ming Deng (4920463)

“…Consistent with the above results, metabolome results showed that there was a decrease in all three identified cyanidins and one delphinidin, the main anthocyanins that determine the color of banana leaves, whereas both transcriptome and reverse transcription–quantitative polymerase chain reaction analysis showed that many key anthocyanin synthesis structural genes and TF regulators were downregulated in MaMYB4 overexpressors. …”

Image 1_SQLE-mediated squalene metabolism promotes tumor immune evasion in pancreatic cancer.tif by Junchen Pan (19417598)

“…Importantly, direct administration of squalene, the metabolic substrate of SQLE, to immune-competent mice bearing KPC pancreatic cancer tumors causes a substantial decrease in CD206+ TAMs and MDSCs, thus releasing immune suppression and inhibiting tumor growth.…”