Optimization of the Malachite-Green ATPase assay for EHD4^ΔN. by Saif Mohd (19251157)

“…<b>B</b> MLG-based ATPase assays for 4 μM EHD4^ΔN, 500 μg/ml DOPS and 50 μM ATP were done at 37°C and 30°C. A further decrease to 25°C did not affect the enzymatic activity compared to 30°C (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0302704#pone.0302704.s002" target="_blank">S2I Fig</a>). …”

Reliable and robust method for abdominal muscle mass quantification using CT/MRI: An explorative study in healthy subjects by Jisuk Park (7405823)

“…In terms of the measurement level, TAMA did not differ from the L2_inf to L4_inf levels, whereas TPA increased with a decrease in measurement level.</p><p>Conclusions</p><p>TAMA is a better biomarker than TPA in terms of inter-scan and inter-reader agreement and robustness to the measurement level. …”

Data_Sheet_3_Generation and Validation of miR-100 Hepatocyte-Specific Knock-Out Mice.PDF by Dong Yang (141041)

“…<p>Background: Inactivation of microRNA-100 (miR-100) is involved in hepatocellular carcinoma (HCC) and miR-100 behaves as a tumor suppressor. To understand miR-100 function in HCC genesis and development in vivo, we developed hepatocyte-specific miR-100 deficient mice.…”

Table_7_The Type I Interferon Pathway Is Upregulated in the Cutaneous Lesions and Blood of Multibacillary Leprosy Patients With Erythema Nodosum Leprosum.DOCX by Thabatta Leal Silveira Andrezo Rosa (5489132)

“…During thalidomide administration, the drug of choice for ENL treatment, a decrease in the mRNA and protein levels of some of these genes both in the skin and blood was observed. …”

Image_2_Resting Heart Rate Variability Is Associated With Subsequent Orthostatic Hypotension: Comparison Between Healthy Older People and Patients With Rapid Eye Movement Sleep Beh... by Yukiyoshi Sumi (5290874)

“…The orthostatic challenge test is a standard autonomic function test that measures a decrease of blood pressure during a postural change from supine to standing positions. …”

Image_1_Resting Heart Rate Variability Is Associated With Subsequent Orthostatic Hypotension: Comparison Between Healthy Older People and Patients With Rapid Eye Movement Sleep Beh... by Yukiyoshi Sumi (5290874)

“…The orthostatic challenge test is a standard autonomic function test that measures a decrease of blood pressure during a postural change from supine to standing positions. …”

Long-range chromatin interactions of κ regulatory elements correlate with V_κ gene usage. by Ralph Stadhouders (523996)

“…<p>(A) Selected examples of genomic regions containing V_κ⁺ fragments, showing increased (V_κ4–57, V_κ6–25, V_κ8–24, V_κ4–79), stable (V_κ8–23–1, V_κ4–78, V_κ13–84), or decreased (V_κ3–9, V_κ14–111) 3C-seq interaction frequencies with 3′Eκ or iEκ upon pre-BCR signaling. …”

DataSheet1_Lysosomal TRPML1 triggers global Ca2+ signals and nitric oxide release in human cerebrovascular endothelial cells.docx by Valentina Brunetti (18861187)

“…Notably, interfering with TRPML1-mediated lysosomal Ca²⁺ mobilization led to a decrease in the free ER Ca²⁺ concentration. …”

DataSheet1_Characteristics of adverse reactions of three anti-glioma drugs in WHO-VigiAccess.ZIP by Huadong Ke (19937268)

“…The analysis revealed that the ten most frequently reported AEs included bone marrow suppression, myalgia, leukopenia, thrombocytopenia, nausea, vomiting, death, rhabdomyolysis, disease progression, and a decrease in neutrophil count. The five most common categories of AEs related to anti-glioma drugs were blood and lymphatic system diseases (20,233 cases, 15.2%), general disorders and administration site conditions (26,973 cases, 20.3%), gastrointestinal dysfunction (22,061 cases, 16.7%), necessitating further investigations (18,285 cases, 13.8%), and musculoskeletal and connective tissue diseases (30,695 cases, 23.1%). …”

Image_3_Microbial Community Redundancy and Resilience Underpins High-Rate Anaerobic Treatment of Dairy-Processing Wastewater at Ambient Temperatures.TIF by Lara M. Paulo (8567841)

“…For example, the main pH shock led to a drop in the methane content to 15%, COD removals decreased to 0%, while the archaeal population decreased to ~11% both at DNA and cDNA levels. …”

Image_2_Genes related to osmoregulation and antioxidation play important roles in the response of Trollius chinensis seedlings to saline-alkali stress.jpg by Rongmiao Hou (14507159)

“…<p>Saline-alkali stress is one of the main abiotic stress factors affecting plant growth and development. Trollius chinensis is a perennial herbal medicinal plant with high values for garden application. …”

Conditional knockout of <i>Ezh2</i> gene in murine hearts caused perinatal lethality. by Li Chen (5749)

“…Semi-quantitative RT-PCR with two different numbers of amplification cycles (30 and 35) was performed on RNA samples purified from WT hearts of E9.5, E10.5, and E11.5. 1 µl or 0.5 µl cDNA from reverse transcription reaction was used for detection of Ezh2 or GAPDH (as a control), respectively. (<b>C</b>) qRT-PCR analysis revealed ∼70% decrease in <i>Ezh2</i> mRNA of <i>Ezh2</i>-cKO heart (n = 3, p<0.001), but <i>Ezh1</i> mRNA was not affected, compared with that of the control littermate hearts. …”

How Does Single Oxygen Atom Addition Affect the Properties of an Fe−Nitrile Hydratase Analogue? The Compensatory Role of the Unmodified Thiolate by Priscilla Lugo-Mas (2406259)

“…Nitrile hydratase (NHase) is one of a growing number of enzymes shown to contain post-translationally modified cysteine sulfenic acids (Cys-SOH). …”

Data_Sheet_8_Global, regional, and national burden of chronic respiratory diseases and associated risk factors, 1990–2019: Results from the Global Burden of Disease Study 2019.ZIP... by Xiang Chen (10398)

“…</p>Results<p>In 2019, 454.56 [95% uncertainty interval (UI): 417.35–499.14] million individuals worldwide had a CRD, showing a 39·8% increase compared with 1990. …”

Data_Sheet_3_Gene Co-expression Network Reveals Potential New Genes Related to Sugarcane Bagasse Degradation in Trichoderma reesei RUT-30.PDF by Gustavo Pagotto Borin (751443)

“…Our results demonstrate a vast range of new promising targets that merit additional studies to improve the cellulolytic potential of T. reesei strains and to decrease the production costs of 2G ethanol.…”

Optogenetic manipulation of slow oscillations. by Ksenia V. Kastanenka (3692380)

“…APP: VSD trace depicting restoration of slow oscillations in APP mice expressing ChR2 virus under CamKIIα promoter when stimulated with light at 0.6 Hz. A decrease in power is evident after light stimulation is stopped. …”

How Does Single Oxygen Atom Addition Affect the Properties of an Fe−Nitrile Hydratase Analogue? The Compensatory Role of the Unmodified Thiolate by Priscilla Lugo-Mas (2406259)

“…Nitrile hydratase (NHase) is one of a growing number of enzymes shown to contain post-translationally modified cysteine sulfenic acids (Cys-SOH). …”

Image_2_Warming and CO2 Enhance Arctic Heterotrophic Microbial Activity.tif by Dolors Vaqué (683567)

“…Results showed that chlorophyll a concentration decreased at increasing temperatures, while BP significantly increased with pCO₂ at 6 and 10°C. …”

Table_1_Microbial Community Redundancy and Resilience Underpins High-Rate Anaerobic Treatment of Dairy-Processing Wastewater at Ambient Temperatures.XLSX by Lara M. Paulo (8567841)

“…For example, the main pH shock led to a drop in the methane content to 15%, COD removals decreased to 0%, while the archaeal population decreased to ~11% both at DNA and cDNA levels. …”

Table_5_Prospective Study Reveals Host Microbial Determinants of Clinical Response to Fecal Microbiota Transplant Therapy in Type 2 Diabetes Patients.xlsx by Dafa Ding (6548732)

“…</p>Results<p>We found that the GM of T2DM patients was reconstituted by FMT. We observed a statistically significant decrease in HbA1c% (from 7.565 ± 0.148 to 7.190 ± 0.210, p<0.01), blood glucose (from 8.483 ± 0.497 to 7.286 ± 0.454 mmol/L, p<0.01), and uric acid (from 309.4 ± 21.5 to 259.1 ± 15.8 µmol/L, p<0.01) while a significant increase in postprandial C-peptide (from 4.503 ± 0.600 to 5.471 ± 0.728 ng/ml, p<0.01) at 12 weeks after FMT. …”