A comprehensive study of glucose and oxygen gradients in a scaled-down model of recombinant HuGM-CSF production in thermoinduced <i>Escherichia coli</i> fed-batch cultures by Greta I. Reynoso-Cereceda (18501789)

“…</p> <p></p><p>Thermoinduced recombinant <i>E. coli</i> grew less in a two-compartment scale-down model.</p><p>Heat-inducible <i>E. coli</i> cultures at a large scale significantly decrease recombinant protein production.…”

Correlation between AOI dwell time and WSD. by Nak Won Rim (10776698)

180 Day Repeated-Dose Toxicity Study on Forchlorfenuron in Sprague–Dawley Rats and Its Effects on the Production of Steroid Hormones by Qian Bu (515803)

“…In addition, it was found that FCF inhibited the proliferation of granulosa cells (GCs) and H295R cells, as well as downregulated the expression of CYP17A1 and CYP19A1 in estradiol and progesterone production, resulting in decreased steroidogenesis in GCs and H295R cells. …”

Table_1_Mechanisms of Pond Expansion in a Rapidly Submerging Marsh.XLSX by Joshua Himmelstein (11497774)

“…We find that as small ponds emerge on the marsh platform, they quickly coalesce and merge, increasing the number of larger ponds. Pond expansion rates are maximized for intermediate size ponds and decrease for larger ponds, where the contribution of wave-driven erosion is negligible. …”

Table_3_Mechanisms of Pond Expansion in a Rapidly Submerging Marsh.XLSX by Joshua Himmelstein (11497774)

“…We find that as small ponds emerge on the marsh platform, they quickly coalesce and merge, increasing the number of larger ponds. Pond expansion rates are maximized for intermediate size ponds and decrease for larger ponds, where the contribution of wave-driven erosion is negligible. …”

Table_2_Mechanisms of Pond Expansion in a Rapidly Submerging Marsh.XLSX by Joshua Himmelstein (11497774)

“…We find that as small ponds emerge on the marsh platform, they quickly coalesce and merge, increasing the number of larger ponds. Pond expansion rates are maximized for intermediate size ponds and decrease for larger ponds, where the contribution of wave-driven erosion is negligible. …”

Discovery of New Inhibitors of Hepatitis C Virus NS3/4A Protease and Its D168A Mutant by Ittipat Meewan (7455041)

“…Hepatitis C virus (HCV) is a human pathogen with high morbidity. The HCV NS3/4A protease is essential for viral replication and is one of the top three drug targets. …”

Mental Imagery, Impact, and Affect: A Mediation Model for Charitable Giving by Stephan Dickert (848967)

“…We propose a model in which identified victim and victim number effects operate through different cognitive and affective mechanisms. …”

Substrate Specificity within a Family of Outer Membrane Carboxylate Channels by Elif Eren (187752)

“…Here we show that OprD channels require a carboxyl group in the substrate for efficient transport, and based on this we have renamed the family Occ, for <u>o</u>uter membrane <u>c</u>arboxylate <u>c</u>hannels. …”

Discrete Covalent Organic–Inorganic Hybrids: Terpyridine Functionalized Polyoxometalates Obtained by a Modular Strategy and Their Metal Complexation by Marie-Pierre Santoni (1295433)

“…Dawson <b>4</b> displays several processes on a wide range of potentials (+0.5 to −2.0 V vs SCE) centered on V(V), W(VI) and the organic ligand in order of decreasing potentials. …”

Discrete Covalent Organic–Inorganic Hybrids: Terpyridine Functionalized Polyoxometalates Obtained by a Modular Strategy and Their Metal Complexation by Marie-Pierre Santoni (1295433)

“…Dawson <b>4</b> displays several processes on a wide range of potentials (+0.5 to −2.0 V vs SCE) centered on V(V), W(VI) and the organic ligand in order of decreasing potentials. …”

Epidermal Growth Factor Receptor-Dependent Mutual Amplification between Netrin-1 and the Hepatitis C Virus by Marie-Laure Plissonnier (337713)

“…Netrin-1 enhanced infectivity of HCV particles and promoted viral entry by increasing the activation and decreasing the recycling of the epidermal growth factor receptor (EGFR), a protein that is dysregulated in HCC. …”

BafA1 attenuates PtdIns3P elevation but does not ameliorate PtdIns(3,5)P₂ reduced by YM201636. by Diego Sbrissa (2653723)

“…YM201636 decreased PtdIns5P and PtdIns(3,5)P₂ and both remained similarly reduced by pretreatment with BafA1. …”

Branched late-steps of the cytosolic iron-sulphur cluster assembly machinery of <i>Trypanosoma brucei</i> by Maiko Luis Tonini (5879708)

“…Ablation of most of the components of the CIA targeting complex by RNAi led to impaired cell growth <i>in vitro</i>, with the exception of <i>Tb</i>CIA2A in procyclic form (PCF) trypanosomes. Depletion of the CIA-targeting complex was accompanied by reduced levels of protein-bound cytosolic iron and decreased activity of an Fe-S dependent enzyme in PCF trypanosomes. …”

Probing the changes in gene expression due to α-crystallin mutations in mouse models of hereditary human cataract by Usha P. Andley (354477)

“…<div><p>The mammalian eye lens expresses a high concentration of crystallins (α, β and γ-crystallins) to maintain the refractive index essential for lens transparency. …”

Exponential-Linear model structure of the transformed cell index (TCI) profile. by Hamanou Benachour (299903)

“…<p>The TCI is decomposed into two parts: a transient and a steady-state periods. This model is composed of three parameters (<i>T,k,r</i>) used as quantitative indicators in the therapeutic efficiency analysis. …”

The small molecule Scaff10-8 inhibits the interaction of the DH domain of AKAP-Lbc and RhoA. by Katharina Schrade (4801266)

“…As expected, excess untagged Rho decreases the binding between GST-RhoA and His-AKAP-Lbc/DHPH in a dose-dependent manner (lower left panel). …”

Kinetic and equilibrium constants for binding of WT and mutant FVIII-C2 proteins to BO2C11. by Jasper C. Lin (685807)

“…<p>Based on the good agreement between the theoretical Rmax (determined using the GE Biacore T100 software) and the measured Rmax values, a 1:1 binding model was determined to be appropriate for these experiments. …”

RORγt-expressing cells attenuate cardiac remodeling after myocardial infarction by Daichi Enomoto (4379605)

“…Finally, the mRNA expression of RORγt, IL-17A, IL-17F and IL-23 receptor (IL-23R) mRNA and protein expression of IL-10 were decreased in RORγt^+/- hearts.…”

Binding of BDD-FVIII muteins to VWF (A-B) and to BO2C11 (C-G). by Jasper C. Lin (685807)

“…</b> Five concentrations of BDD-FVIII-F2196K were injected over the BO2C11-Fab biosensor surface. This mutein showed a ~100X faster off-rate and a 28-fold decreased affinity for BO2C11-Fab compared to WT-BDD-FVIII. …”