Feasibility of Simplification From a Basal-Bolus Insulin Regimen to a Fixed-Ratio Formulation of Basal Insulin Plus a GLP-1RA or to Basal Insulin Plus an SGLT2 Inhibitor: BEYOND, a... by Dario Giugliano (10218354)

“…The primary efficacy outcome was change from baseline in HbA1c at 6 months. </b><b></b></p> <p><b>RESULTS</b></p> <p><b>Baseline characteristics were similar among the 3 groups (mean HbA1c was 8.6%, 70 mmol/mol). …”

Resveratrol Prevents Oxidative Stress-Induced Senescence and Proliferative Dysfunction by Activating the AMPK-FOXO3 Cascade in Cultured Primary Human Keratinocytes by Yasuo Ido (172159)

“…<div><p>The aging process is perceived as resulting from a combination of intrinsic factors such as changes in intracellular signaling and extrinsic factors, most notably environmental stressors. …”

Relationships between adverse childhood experience (ACE) categories among ever-partnered Sri Lankan men (n = 1252), UN Multi-Country Study on Men and Violence in Asia and the Pacif... by Ruvani W. Fonseka (785909)

Prevalence of intimate partner violence (IPV) perpetration across adverse childhood experience (ACE) categories and selected covariates among ever-partnered Sri Lankan men (n = 125... by Ruvani W. Fonseka (785909)

Linear-Scaling Local Natural Orbital CCSD(T) Approach for Open-Shell Systems: Algorithms, Benchmarks, and Large-Scale Applications by P. Bernát Szabó (10526316)

“…While the protein models involve difficulties for local approximations, such as the spin states of a bounded iron ion or an extremely delocalized singly occupied orbital, the corresponding single-node LNO-CCSD­(T) computations were feasible in a matter of days with 10s to 100 GB of memory use. …”

Effects of H₂O₂, insulin and resveratrol on ³H -thymidine incorporation in human primary keratinocytes. by Yasuo Ido (172159)

Resveratrol increases FOXO3 transcriptional activity and expression of FOXO3 target genes. by Yasuo Ido (172159)

Parents’ Education Shapes, but Does Not Originate, the Disability Representations of Their Children by Fabio Meloni (751136)

“…Four questionnaires were administered to a sample of 76 primary school aged children and one of their parents (n = 152). …”

Supplementary file 1_Monitoring the dual-season hydrological dynamics of the Pong reservoir in Himachal Pradesh, India.docx by Rajesh Sarda (13162317)

“…The study employed a spatial linear trend modelling approach to identify trends in relative water depth, revealing a decreasing trend and a quantifiable reduction in the reservoir’s depth for both seasons. …”

Functional Analysis of Sirtuin Genes in Multiple <i>Plasmodium falciparum</i> Strains by Catherine J. Merrick (689450)

“…In 3D7, complementation of the PfSir2a genetic disruption resulted in a significant decrease in previously-elevated <i>var</i> gene expression levels, but with the continued expression of multiple <i>var</i> genes. …”

Methylation Levels of <i>SLC23A2</i> and <i>NCOR2</i> Genes Correlate with Spinal Muscular Atrophy Severity by Galina Yu. Zheleznyakova (714444)

“…In contrast to type I SMA male patients, type III-IV patients demonstrated a 16% decrease in the methylation levels of a target CpG site, belonging to the 5’UTR of <i>NCOR2</i>. …”

DataSheet_1_RNASE2 Mediates Age-Associated B Cell Expansion Through Monocyte Derived IL-10 in Patients With Systemic Lupus Erythematosus.pdf by Yantong Zhu (12112137)

“…<p>Systemic lupus erythematosus (SLE) is characterized by the production of pathogenic autoantibodies. Ribonuclease A family member 2 (RNase2) is known to have antiviral activity and immunomodulatory function. …”

Knockdown of FOXO3 attenuates the suppression of H₂O₂-induced senescence by resveratrol. by Yasuo Ido (172159)

Time-kill studies with 5 strains of <i>K</i>. <i>pneumoniae</i>, <i>P</i>. <i>aeruginosa</i>, <i>S</i>. <i>maltophilia</i> with concentration equal to one fold (A) or two fold (B)... by Antoine Grillon (519642)

Effect of cell shapes on cluster sizes. by Mrinmoy Mukherjee (5463848)

“…<p>(A) The mean cluster size () of H cells as a function of targeted perimeter of the H cells (<i>p</i>₀) for different values of <i>μ</i> at Γ = 3 calculated at mcs = 50000. is similar for <i>p</i>₀ = [23, 25] and decreases gradually with either an increase or decrease in <i>p</i>₀. …”

Allocating Police Resources While Limiting Racial Inequality by Andrew P. Wheeler (4529650)

“…Using data on stops and crime in New York City, I show that police stops can be more equitably distributed according to race, but there are fundamental trade-offs. One cannot gain a racial distribution of stops proportionately equal to the residential population without large decreases in the efficiency of targeting high crime areas. …”

EBV-encoded genes with a log₂ fold-change in LCLs-WT compared with LCLs-dBNRF1 in RNA-seq analyses. by Ken Sagou (1945318)

Physical and elemental properties of soil materials and biochar. by Rebecca T. Barnes (633895)

Image3_Association Among the Gut Microbiome, the Serum Metabolomic Profile and RNA m6A Methylation in Sepsis-Associated Encephalopathy.jpg by Hui Wang (30400)

“…</p><p>Results: In the SAE group, the IL-6, ICAM-5 and METTL3 levels were significantly more than those in the non-SAE group, while the FTO levels were significantly decreased in the SAE group. The diversity was decreased in the SAE gut microbiome, as characterized by a profound increase in commensals of the Acinetobacter, Methanobrevibacter, and Syner-01 genera, a decrease in [Eubacterium]_hallii_group, while depletion of opportunistic organisms of the Anaerofilum, Catenibacterium, and Senegalimassilia genera were observed in both groups. …”

Table_1_Curcuma longa extract reduces serum inflammatory markers and postprandial hyperglycemia in healthy but borderline participants with overweight and glycemia in the normal/pr... by Ryusei Uchio (17862527)

“…First, we investigated the effect of CLE and the potential active components of C. longa on lipopolysaccharide-induced inflammation in RAW264.7 macrophages. We found a significant decrease in the production of interleukin (IL)-1β, IL-6, tumor necrosis factor (TNF)-α, and nitric oxide with CLE, turmeronol A, and bisacurone, Significant inhibition of each of these substances was also observed, except for TNF-α with turmeronol B. …”