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46521
Ganaxolone: A Review in Epileptic Seizures Associated with Cyclin‑Dependent Kinase‑Like 5 Deficiency Disorder
Published 2024“…While somnolence and sedation are related to the dose of ganaxolone, they appear early in treatment and may decrease with continued therapy. Thus, although current evidence is somewhat limited, adjunctive ganaxolone could be a valuable therapeutic option for patients aged 2–17 years with epileptic seizures associated with CDD.…”
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46522
Increased adherence to treatment guidelines in patients with urinary tract infection in primary care: A retrospective study
Published 2019“…</p><p>Results</p><p>There was a variability in consultation incidence for LUTI with an increase between 2008 and 2010 and a decrease between 2010 and 2013, resulting in a slight rise in consultation incidence between 2008 and 2013. …”
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46523
Table_4_Lipid-lowering medications and risk of malignant melanoma: a Mendelian randomization study.xlsx
Published 2024“…</p>Results<p>IVW analysis revealed that HMGCR gene expression is linked to a decreased risk of melanoma [OR: 0.624(0.439–0.888); p = 0.008]. …”
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46524
Table_1_Coffee Microbiota and Its Potential Use in Sustainable Crop Management. A Review.XLSX
Published 2020“…Nowadays, next-generation sequencing technologies allow to study coffee associated microorganisms with a metabarcoding/metagenomic approach. This strategy, which does not require cultivating microorganisms, now provides a deeper insight in the coffee-associated microbial communities and their implication not only in the coffee plant fitness but also in the quality of the final product. …”
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46525
Table_1_Assessment of Hypertension Using Clinical Electrocardiogram Features: A First-Ever Review.pdf
Published 2020“…<p>Hypertension affects an estimated 1.4 billion people and is a major cause of morbidity and mortality worldwide. …”
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46526
Table_1_Electrocardiographic phenotype of exercise-induced arrhythmogenic cardiomyopathy: A retrospective observational study.pdf
Published 2022“…At peak exercise the most striking finding was a significant decrease of the R/L duration ratio in individuals with ACM, which was the result of lateral precordial QRS prolongation.…”
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46527
Table_2_Coffee Microbiota and Its Potential Use in Sustainable Crop Management. A Review.XLSX
Published 2020“…Nowadays, next-generation sequencing technologies allow to study coffee associated microorganisms with a metabarcoding/metagenomic approach. This strategy, which does not require cultivating microorganisms, now provides a deeper insight in the coffee-associated microbial communities and their implication not only in the coffee plant fitness but also in the quality of the final product. …”
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46528
Leisure-time physical activity in São Paulo adults: a trend analysis from 2006 to 2016
Published 2021“…There was a decrease in walking and playing soccer and there was an increase in doing gymnastics. …”
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46529
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46530
High-quality and anti-inflammatory diets and a healthy lifestyle are associated with lower sleep apnea risk
Published 2022“…There was a significant interaction between healthy lifestyle and sex with sleep apnea risk (P for interaction = .049) whereby females with higher healthy lifestyle scores had a lower risk of sleep apnea compared to males. …”
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46531
Data_Sheet_1_Perioperative Propranolol Against Dental Anxiety: A Randomized Controlled Trial.DOC
Published 2022“…Background<p>Promising results from a trauma reactivation study on post-traumatic stress disorder suggest that propranolol is capable of attenuating symptoms of traumatically induced mental disorders by blocking memory reconsolidation.…”
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46532
Data_Sheet_1_Altered gut fungi in systemic lupus erythematosus – A pilot study.docx
Published 2022“…Compared with HCs, the alpha and beta diversities of fungal microbiota decreased in SLE patients. According to principal coordinates analysis results, the constitution of fungal microbiota from SLE, RA, UCTDs patients and HCs exhibited distinct differences with a clear separation between fungal microbiota. …”
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46533
Host genetic variants potentially associated with SARS-CoV-2: A multi-population analysis
Published 2020“…In this report, we aimed at exploring the frequency of a set of genetic polymorphisms that could affect SARS-CoV-2 susceptibility or severity, including those that were previously associated with SARS-CoV-1. …”
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46534
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46535
Changes in Dietary Fat Intake and Projections for Coronary Heart Disease Mortality in Sweden: A Simulation Study
Published 2016“…</p><p>Methods</p><p>We compared the effect on future CHD mortality of two different scenarios for fat intake a) <i>daily SFA intake decreasing to 10 energy</i> percent <i>(E%)</i>, and b) <i>daily SFA intake rising to 20 E%</i>. …”
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46536
Table 3_Unveiling the immunological landscape of disseminated tuberculosis: a single-cell transcriptome perspective.xlsx
Published 2025“…T cell pseudotime analysis indicated a decrease in the expression of most hypervariable genes over time, pointing to T cell functional exhaustion. …”
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46537
Long-term retrospective assessment of a transmission hotspot for human alveolar echinococcosis in mid-west China
Published 2019“…</p><p>Methodology/Findings</p><p>We subsequently undertook follow-up eco-epidemiological studies based on human population screening and dog survey, in 2005/6 and in 2014/15. Our observations show a decrease in human AE prevalence, especially marked in the 11–30 year old age category. …”
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46538
Image 3_Unveiling the immunological landscape of disseminated tuberculosis: a single-cell transcriptome perspective.jpeg
Published 2025“…T cell pseudotime analysis indicated a decrease in the expression of most hypervariable genes over time, pointing to T cell functional exhaustion. …”
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46539
Macrophages Mediate a Switch between Canonical and Non-Canonical Wnt Pathways in Canine Mammary Tumors
Published 2014“…These observations indicate that rather than being “corrupted” by cancer cells, TAMs constitutively secrete canonical Wnt inhibitors that decrease tumor proliferation and development, but as a side effect, they induce the non-canonical Wnt pathway, which leads to tumor metastasis.…”
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46540
Table1_Does autoimmune diseases increase the risk of frailty? A Mendelian randomization study.doc
Published 2024“…Conversely, MS appears to be associated with a potential decrease in the risk of frailty.</p>…”