Cysteine Dioxygenase 1 Is a Tumor Suppressor Gene Silenced by Promoter Methylation in Multiple Human Cancers by Mariana Brait (130972)

“…Expression of <em>CDO1</em> was tightly controlled by promoter methylation, suggesting that promoter methylation and silencing of <em>CDO1</em> may be a common event in human carcinogenesis. Moreover, forced expression of full-length <em>CDO1</em> in human cancer cells markedly decreased the tumor cell growth in an <em>in vitro</em> cell culture and/or an <em>in vivo</em> mouse model, whereas knockdown of <em>CDO1</em> increased cell growth in culture. …”

Proteomics and Metabolomics Analyses Reveal a Dynamic Landscape of Coal Workers’ Pneumoconiosis: An Insight into Disease Progression by Yangyang Wei (436909)

“…Integrated analysis found that ABC transporters are a shared pathway among the three groups, and ABCD2 is involved in the ABC transporter pathway. …”

Data Sheet 1_Identification of a neuron-specific ferroptosis in the neurodegenerative mucopolysaccharidosis III model.pdf by Mathilde Larribau (20893280)

“…Our results showed elevated iron levels, decreased mRNA expression of TFR1 and ZIP14 (involved in iron uptake) at 9 months of age, and increased protein levels of FTH (which stores intracellular iron) in MPSIIIB brains, indicating a potential link to ferroptosis. …”

Video_1_Bidirectional Optogenetic Modulation of the Subthalamic Nucleus in a Rodent Model of Parkinson’s Disease.WMV by Caroline Xie (12553255)

“…<p>Parkinson’s disease (PD) is a neurodegenerative disorder characterized by a range of motor symptoms. …”

Data_Sheet_1_Neuronal ICAM-5 Plays a Neuroprotective Role in Progressive Neurodegeneration.PDF by Katharina Birkner (150156)

“…In humans, cerebrospinal fluid from patients suffering from progressive forms of MS shows decreased sICAM-5 levels, suggesting a lack of this endogenous protective pathway in these patient groups. …”

Table 1_Association between immune cells and urticaria: a bidirectional Mendelian randomization study.xlsx by Yongjun Chen (577347)

“…First, by utilizing Genome-wide Association Study (GWAS) data, we identified 31 immunophenotypes associated with urticaria risk, with 18 increasing and 13 decreasing the risk. Through rigorous criteria, we identified 4 immunophenotypes that have a strong causal relationship with urticaria. …”

Image 3_Changes in gut flora in patients with epilepsy: a systematic review and meta-analysis.jpg by Xingyan He (20198118)

“…Background<p>Epilepsy is a prevalent chronic neurological disorder that is strongly associated with a wide range of psychological, cognitive and social problems. …”

A Heat-Shock Protein Axis Regulates VEGFR2 Proteolysis, Blood Vessel Development and Repair by Alexander F. Bruns (121599)

“…A mouse femoral artery model showed that HSP90 inhibition also blocked blood vessel repair <em>in vivo</em> consistent with decreased endothelial regeneration. …”

Image 1_Entropy as a marker of physiological transition during pediatric cardiopulmonary exercise testing.jpeg by Kaleigh O’Hara (22750082)

“…<p>This research analyzed the sample entropy (SampEn) of breath-by-breath cardiopulmonary exercise testing (CPET) data from 170 healthy pediatric participants (85 males) 8 to 18-years-old, using a Bayesian statistics approach. SampEn measures the complexity of time series data, providing quantitative insight into the predictability of breathing patterns in pediatric participants. …”

Table4_Inflammatory-Metal Profile as a Hallmark for COVID-19 Severity During Pregnancy.xlsx by Johana Vásquez-Procopio (13217553)

“…Robust negative correlations between iron/magnesium and zinc/IL-6, and a positive correlation between copper/IP-10 were observed in pregnant women with the severe form of the disease. …”

Image_1_Case Report: Tachycardia, Hypoxemia and Shock in a Severely Burned Pediatric Patient.JPEG by Jianshe Shi (12880178)

“…</p>Case presentation<p>A 4.5-year-old girl was admitted to our hospital 30 h after a severe burn injury. …”

AMPK Is Involved in the Regulation of Incretin Receptors Expression in Pancreatic Islets under a Low Glucose Concentration by Kazuki Tajima (414868)

“…The phosphorylation of AMPK in the mouse islets was decreased by increasing glucose concentrations. We showed the expression of incretin receptors in bell-shaped response to glucose; Expression of the incretin receptors in the isolated islets showed higher levels under a medium glucose concentration (11.1 mM) than that under a low glucose concentration (2.8 mM), but was suppressed under a high glucose concentration (22.2 mM). …”

Synthesis, Properties, and Reactions of a Series of Stable Dialkyl-Substituted Silicon−Chalcogen Doubly Bonded Compounds by Takeaki Iwamoto (1391731)

Intestinal Serum amyloid A suppresses systemic neutrophil activation and bactericidal activity in response to microbiota colonization by Caitlin C. Murdoch (6432923)

“…These results indicate Saa produced by the intestine in response to microbiota serves as a systemic signal to neutrophils to restrict aberrant activation, decreasing inflammatory tone and bacterial killing potential while simultaneously enhancing their ability to migrate to wounds.…”

Table_2_A Comprehensive RNA Expression Signature for Cervical Squamous Cell Carcinoma Prognosis.docx by Jie Xiong (138164)

“…This study aimed to develop a comprehensive transcriptomic signature for CESC patient prognosis. …”

Image_3_Patterns of Microbiome Composition Vary Across Spatial Scales in a Specialist Insect.tiff by Kyle J. Paddock (12716924)

“…We found that bacterial communities of WCR and NCR shared a portion of their bacterial communities even when collected from disparate locations. …”

A simplified model for coordinated regulation of JA responses by JAZ-targeted transcription activators and transcription repressors. by Susheng Song (266068)

“…<p>(A) JAZ proteins interact with transcription activators (such as MYC2, TT8 and MYB75) and transcription repressors (including bHLH3, bHLH13, bHLH14 and bHLH17) to attenuate their transcriptional function. …”

VEGF distribution and VEGFR occupancy for a total receptor density of 10,000 per endothelial cells. by Marianne O. Stefanini (255308)

“…<p>The scenarios correspond to those in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1000622#pcbi-1000622-g006" target="_blank">Figure 6B</a>. …”

Proteomics and Metabolomics Analyses Reveal a Dynamic Landscape of Coal Workers’ Pneumoconiosis: An Insight into Disease Progression by Yangyang Wei (436909)

“…Integrated analysis found that ABC transporters are a shared pathway among the three groups, and ABCD2 is involved in the ABC transporter pathway. …”

A Tale of Switched Functions: From Cyclooxygenase Inhibition to M-Channel Modulation in New Diphenylamine Derivatives by Asher Peretz (44240)

“…Powerful M-channel openers were generated, provided that the diphenylamine moiety and a terminal hydroxyl group are preserved. In transfected CHO cells, they activated recombinant Kv7.2/3 K⁺ channels, causing a hyperpolarizing shift of current activation as measured by whole-cell patch-clamp recording. …”