Mitochondrial Apoptotic Pathway Is Activated by H₂O₂-Mediated Oxidative Stress in BmN-SWU1 Cells from <i>Bombyx mori</i> Ovary by Peng Chen (6514)

“…Furthermore, western blot analysis revealed a significant increase in p53 and cytochrome c expression, and a decrease in Bcl-2 expression compared to the controls. …”

Image2_Sodium–Glucose CoTransporter-2 Inhibitor Empagliflozin Ameliorates Sunitinib-Induced Cardiac Dysfunction via Regulation of AMPK–mTOR Signaling Pathway–Mediated Autophagy.JPE... by Changzhen Ren (10649432)

“…We aimed to determine whether empagliflozin (EMPA), an SGLT2 inhibitor, has a protective role against sunitinib (SNT)-induced cardiac dysfunction in a mouse model.…”

Impact of Manganese Carbonate Precipitation on Uranium(VI) Fate in Conditions Relevant to Carbonate-Buffered Aquifers by Surya Sujathan (11355082)

“…Reactive modeling of Mn and DIC data exhibited a decrease in the surface area normalized rate constants of MnCO_3(s) precipitation from 5.9 to 3.3 × 10^–8 mol m^–2 h^–1 with an increase in initial U(VI) from 0 to 500 μM. …”

Evaporation rates of cinnamon essential oil. by Thummanoon Boonmee (17935566)

“…Cardboard piece showed a higher absorption capacity of cinnamon compared to citronella and clove. …”

Image1_Effect of Rumex dentatus on Gastrointestinal Protection and Toxicology in Rodents via Investigating H+/K+-ATPase, Calcium Channels, and PDE Mediated Signaling.tiff by Neelam Gul Qazi (13178827)

“…Extracts and emodin also show an inhibitory effect against H⁺/K⁺-ATPase. Rumex dentatus showed a gastroprotective and antioxidant effect. Histopathological evaluation showed improvement in cellular architecture and decrease in the expression of inflammatory markers such as cyclooxygenase (COX2), tumor necrosis factor (TNF-α), and phosphorylated nuclear factor kappa B (p-NFƙB), validated through immunohistochemistry, ELISA, and western blot techniques. …”

Transcript levels of dsRNA-treated sporocysts 7 days after dsRNA exposure. by Marina de Moraes Mourão (189239)

“…Colored bars represent sporocyst mRNA levels showing consistent and statistically significant decrease (dsRNA-Smad4/GFP, <i>P</i> = 0.0056; -lactate dehydrogenase/GFP, <i>P</i> = 0.0358; -Cav2A/GFP, <i>P</i> = 0.0136; -EF1α/GFP, <i>P</i> = 0.0358; -calcineurin B/GFP, <i>P</i> = 0.0189; -GST26/GFP, <i>P</i> = 0.0136; -SmZF1/GFP, <i>P</i> = 0.0189; -fibrillarin/GFP, <i>P</i> = 0.0407; -GST28/GFP, <i>P</i> = 0.0284; -GPx/GFP, <i>P</i> = 0.0269 and -TPx1/GFP, <i>P</i> = 0.0358/-TPx2/GFP, <i>P</i> = 0.0358) or increase (dsRNA-SOD/GFP, <i>P</i> = 0.0294) in target transcript levels when compared to the GFP-dsRNA control treatment. …”

DataSheet1_Long term high glucose exposure induces premature senescence in retinal endothelial cells.pdf by Pietro Maria Bertelli (13431426)

“…The retina from db/db mice showed a significant increase in acellular capillaries associated with a significant decrease in vascular density in the intermediate and deep retinal plexuses, when compared to db/+ mice. …”

DFT Studies on Styrene Polymerization Catalyzed by Cationic Rare-Earth-Metal Complexes: Origin of Ligand-Dependent Activities by Xingbao Wang (1446433)

“…The calculated results also suggest that a longer alkyl chain of the side arm of the ancillary ligand could deter monomer coordination and thus decrease the polymerization activity.…”

Supplementary Material for: Therapeutic Effects of Add-On Tenapanor for Hemodialysis Patients with Refractory Hyperphosphatemia by Shigematsu T. (4106377)

“…<b><i>Discussion/Conclusion:</i></b> Therapy with existing phosphate binders and add-on tenapanor resulted in a significant decrease in serum phosphorus level compared with the placebo group in patients with refractory hyperphosphatemia despite treatment with phosphate binders. …”

Data_Sheet_1_Critical Role of TLR4 on the Microglia Activation Induced by Maternal LPS Exposure Leading to ASD-Like Behavior of Offspring.doc by Lu Xiao (314030)

“…The protein expression levels of TLR4 signaling pathways, including TLR4, Phospho-NFκB p65, IKKα, and IBA-1, iNOS expression were increased in the LPS-treated WT offspring, whereas Arg-1 was decreased. Maternal LPS treatment resulted in the significant reduction in the levels of the synaptic pruning-related proteins, C3 and CR3A. …”

Supplementary file 2_Wuzi-Yanzong-Wan inhibits testicular mitochondrial apoptosis in rats by downregulating TAp73-Mediated P38 MAPK-ADAM17 pathway.docx by Ziao Liu (8938748)

“…Mechanistic investigations revealed that WZYZW markedly suppressed germ cell apoptosis (flow cytometry confirmed a significant decrease in apoptotic cell proportion) and attenuated DNA damage (indicated by significantly reduced γ-H2AX (a DNA damage marker) fluorescence intensity). …”

<i>Spidey</i> expression during development is essential for adult survival. by Yin Ning Chiang (1718815)

“…<p>(<b>A</b>) Silencing <i>spidey</i> expression from 0–72 hours after egg laying (AEL) results in pharate lethality of males and females. …”

Probing the Limits of Alkaline Earth–Transition Metal Bonding: An Experimental and Computational Study by Matthew P. Blake (1522120)

“…DFT calculations in combination with Ziegler Rauk energy decomposition and atoms in molecules analysis were used to assess the nature and energy of Ae–Co bonding in a series of model compounds. The Ae–Co interaction energies decrease from Be to Sr, and toward the bottom of the group, side-on (η²) CO ligand coordination competes with Ae–Co bonding. …”

Image_2_Alleviation of Detrimental Effects of Salt Stress on Date Palm (Phoenix dactylifera L.) by the Application of Arbuscular Mycorrhizal Fungi and/or Compost.TIF by Mohamed Ait-El-Mokhtar (9342305)

“…Plants grown in soil amended with compost under salt stress showed an improvement particularly in K⁺ and proline content and a decrease in H₂O₂ concentration compared to controls under the saline condition. …”

Characteristics of the study sample. by Nand Lal Banstola (10510379)

“…</p><p>Findings</p><p>All four districts showed a decrease in case notification rates since 2015, with the steepest decline in the intervention districts. …”

Effects of Corroded and Non-Corroded Biodegradable Mg and Mg Alloys on Viability, Morphology and Differentiation of MC3T3-E1 Cells Elicited by Direct Cell/Material Interaction by Sepideh Mostofi (3147717)

“…The most pronounced difference in surface morphology, namely crystal formation, was observed when Pure Mg and Mg2Ag were immersed in cell medium for 8 days, and was associated with an increase in atomic % of oxygen and a decrease of surface calcium and phosphorous. …”

NSUN2-mediated m⁵C methylation of IRF3 mRNA negatively regulates type I interferon responses during various viral infections by Hongyun Wang (225359)

“…Together, our findings reveal that NSUN2 serves as a negative regulator of interferon response by accelerating the fast turnover of <i>IRF3</i> mRNA, while endogenous NSUN2 levels decrease during SARS-CoV-2 and various viral infections to boost antiviral responses for effective elimination of viruses.…”

Effect of Intramuscular Injection of pH, lactate, ATP, and α,β–meATP on Muscle Withdrawal Threshold. by Nicholas S. Gregory (796912)

“…Of these doses, only pH 4.0 saline produced a significant decrease in muscle withdrawal threshold from baseline (Repeated measures ANOVA, F_4,31 = 16.761, p <0.001, Tukey test, p < 0.001). …”

Table_1_Lipoamide Alleviates Oxidized Fish Oil-Induced Host Inflammatory Response and Oxidative Damage in the Oviduct of Laying Hens.docx by Qingxiu Liu (739695)

“…Of note, the supplementation of LAM could significantly increase the laying performance, improve the levels of serum immunoglobulins (IgA, IgG, and IgM), serum estrogen [progesterone (P) and estradiol (E2)], and serum antioxidant parameters (T-AOC, T-SOD, GSH-Px, GSH, GR, CAT, and HRSA) and decrease the concentrations of serum inflammatory cytokines (TNF-α, IL-6, IL-8, and INF-γ) in laying hens following OFO administration (p < 0.05). …”

Table1_Thermodynamic Properties of Fe-Bearing Wadsleyite and Determination of the Olivine-Wadsleyite Phase Transition Boundary in (Mg,Fe)2SiO4 System.XLSX by Chang Su (170990)

“…The results not only confirm the feasibility of the Clausius-Clapeyron equation in obtaining the solid-solid phase transition, but also suggest that the existence of Fe might decrease the transition pressure of olivine-wadsleyite, which would consequently cause a higher temperature at the 410 km discontinuity.…”