VCU AAFS Poster.pdf by Caitlin Lydon (20721863)

“…Samples that had been aged for more than two months showed a 40% decrease in median autofluorescence (~400RFU) which was consistent across each contributor tested. …”

Phytochemicals as Micronutrients: What Is their Therapeutic Promise in the Management of Traumatic Brain Injury? by Al-Haj, Nadine

“…In this regards, phytochemicals have been acknowledged to cause a significant decrease in neuronal injury through different mechanisms including the activation of the Nrf2 transcription factor leading to activation of several antioxidant enzyme systems such as superoxide dismutase, inhibition of NADPH oxidases (NOX) enzymes, suppression of nuclear factor kappa B (NF-κB) activity and reduction of the release of inflammatory mediators, suppression of the NLRP3 inflammasome, stimulation of neurogenesis by activating neurotrophic factors (BDNF), among others. …”
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Kaplan-Meier plot. by Nand Lal Banstola (10510379)

“…</p><p>Findings</p><p>All four districts showed a decrease in case notification rates since 2015, with the steepest decline in the intervention districts. …”

Somatic expression of <i>lin-35(+)</i> partially rescues <i>lin-35</i> mutant fertility defects. by Brian P. Mikeworth (16274376)

“…<i>P-</i>value ≤ 0.05 using a Fisher’s exact test. (D) The decrease in fertility with moderate temperature stress represented by the percentage of the mean brood size remaining with upshift or at 26°C compared to 20°C within the same strain. …”

Table_1_MiR-132-3p Modulates MEKK3-Dependent NF-κB and p38/JNK Signaling Pathways to Alleviate Spinal Cord Ischemia-Reperfusion Injury by Hindering M1 Polarization of Macrophages.D... by Hua Fang (627909)

“…<p>Spinal cord ischemia-reperfusion (SCIR) injury is a serious complication of open surgical and endovascular aortic procedures. …”

Release rates of essential oils. by Thummanoon Boonmee (17935566)

“…Cardboard piece showed a higher absorption capacity of cinnamon compared to citronella and clove. …”

Aberrant plasma MMP and TIMP dynamics in Schistosoma - Immune reconstitution inflammatory syndrome (IRIS) by Odin Goovaerts (138054)

“…We report persistent plasma levels of MMP-10, along with a more pronounced decrease in TIMP-1 and ANA-levels, and low levels of TIMP-2 during 3 months of ART. …”

Image5_Effect of Rumex dentatus on Gastrointestinal Protection and Toxicology in Rodents via Investigating H+/K+-ATPase, Calcium Channels, and PDE Mediated Signaling.tiff by Neelam Gul Qazi (13178827)

“…Extracts and emodin also show an inhibitory effect against H⁺/K⁺-ATPase. Rumex dentatus showed a gastroprotective and antioxidant effect. Histopathological evaluation showed improvement in cellular architecture and decrease in the expression of inflammatory markers such as cyclooxygenase (COX2), tumor necrosis factor (TNF-α), and phosphorylated nuclear factor kappa B (p-NFƙB), validated through immunohistochemistry, ELISA, and western blot techniques. …”

DataSheet_1_The neutrophil elastase inhibitor, sivelestat, attenuates acute lung injury in patients with cardiopulmonary bypass.docx by Tuo Pan (9264234)

“…Background<p>The sivelestat is a neutrophil elastase inhibitor thought to have an effect against acute lung injury (ALI) in patients after scheduled cardiac surgery. …”

Table_4_AMF Inoculation Can Enhance Yield of Transgenic Bt Maize and Its Control Efficiency Against Mythimna separata Especially Under Elevated CO2.DOCX by Long Wang (95893)

“…However, studies have shown that Bt crops will face a new risk due to a decrease in exogenous toxin content under elevated carbon dioxide (CO₂) concentration, thus negatively affecting the ecological sustainability of Bt crops. …”

DataSheet2_Toxicological safety evaluation of Qin-Zhi-Zhu-Dan formula in rats during the treatment and recovery periods.PDF by Wenxiu Xu (1922206)

“…SD rats were randomly divided into control group and treatment groups of A (0.5 g/kg/d QZZD), B (1.5 g/kg/d QZZD), and C (5.0 g/kg/d QZZD). …”

Increased BMP/TGFB signaling pathway activity in <i>Rx > cre Myrf</i>^<i>fl/fl</i> mutants. by Michelle L. Brinkmeier (18709048)

“…(C-<i>Myrf</i>^<i>fl/fl</i>; M-<i>Rx > cre Myrf</i>^<i>fl/fl</i>) (B) VlnPlot representation of transcript levels of <i>Wfikkn2</i>, <i>Tgfb2,</i> and <i>Id3</i> in theRPE cluster highlighting a decrease in the pathway inhibitor, <i>Wfikkn2</i> and increases in <i>Tgfb2</i> and <i>Id3</i>. …”

Image_1_Cover crop-based reduced tillage management impacts organic squash yield, pest pressure, and management time.jpg by Dylan Bruce (13913982)

“…In addition, rye resulted in lower marketable yield due to higher proportion unmarketable fruit in 2018, likely related to a 25 cm rain event 2 weeks prior to harvest. A significant row mulch × aisle mulch interaction was observed for marketable fruit m⁻¹, showing that yield was not significantly affected by the type of in-row mulch in plots with crimped rye mulch in the aisle. …”

Table_1_Cover crop-based reduced tillage management impacts organic squash yield, pest pressure, and management time.docx by Dylan Bruce (13913982)

“…In addition, rye resulted in lower marketable yield due to higher proportion unmarketable fruit in 2018, likely related to a 25 cm rain event 2 weeks prior to harvest. A significant row mulch × aisle mulch interaction was observed for marketable fruit m⁻¹, showing that yield was not significantly affected by the type of in-row mulch in plots with crimped rye mulch in the aisle. …”

Cell loss is further exacerbated in E11.5 <i>Sphk1−/−;Sphk2−/−</i> trigeminal ganglion. by Hui Meng (197494)

“…<p>(<b>A–C</b>) E11.5 (40–42 somites) trigeminal ganglia from wild type, <i>Sphk1−/−;Sphk2+/−</i>, and <i>Sphk1−/−;Sphk2−/−</i> were immunostained with antibodies to act-Casp-3 <b>(red, arrowhead)</b> and islet-1/2 <b>(green, nuclear)</b>. …”

Efficient Lewis Acid Promoted Alkene Hydrogenations Using Dinitrosyl Rhenium(−I) Hydride Catalysts by Yanfeng Jiang (1873795)

“…Highly efficient alkene hydrogenations were developed using NO-functionalized hydrido dinitrosyl rhenium catalysts of the type [ReH­(PR₃)₂(NO)­(NO­(LA))]­[Z] (<b>2</b>, LA = B­(C₆F₅)₃; <b>3</b>, LA = [Et]⁺, Z = [B­(C₆F₅)₄]⁻; <b>4</b>, LA = [SiEt₃]⁺, Z = [HB­(C₆F₅)₃]⁻; R = <i>i</i>Pr <b>a</b>, Cy <b>b</b>). Lewis acid attachment to the NO ligand was found to facilitate bending at the N_OLA atom and concomitantly to open up a vacant site at the rhenium center. …”

6-Hydroxydopamine induces secretion of PARK7/DJ-1 via autophagy-based unconventional secretory pathway by Yasuomi Urano (685567)

“…We moreover observed that 6-OHDA-derived electrophilic quinone induced oxidative stress as indicated by a decrease in glutathione levels, and that this was suppressed by pretreatment with antioxidant NAC. …”

Schematic diagram summarizing the transcriptional data obtained for the liver, muscle and adipose tissue and the results of epigenetic studies in OP1, OP2 and OR2 mice. by Linda Attig (122203)

“…In the livers of OP1 mice, DNA hypomethylation was associated with an upregulation of <i>Suv39h1</i> and <i>Suv39h2</i> expression, whereas, in both OR2 and OP2 mice, normal DNA methylation was associated with a decrease in <i>Jhdm2a</i> expression and an increase in the level of <i>Dnmt2</i> mRNA. …”

Image_1_Fecal Microbial and Metabolic Profiles in Dogs With Acute Diarrhea Receiving Either Fecal Microbiota Transplantation or Oral Metronidazole.pdf by Jennifer Chaitman (8719770)

“…In the FMT group, the DI decreased over time, while MET led to a significant increase in the dysbiosis index at day 7 and 28 compared to FMT. …”

Image1_Sodium–Glucose CoTransporter-2 Inhibitor Empagliflozin Ameliorates Sunitinib-Induced Cardiac Dysfunction via Regulation of AMPK–mTOR Signaling Pathway–Mediated Autophagy.JPE... by Changzhen Ren (10649432)

“…We aimed to determine whether empagliflozin (EMPA), an SGLT2 inhibitor, has a protective role against sunitinib (SNT)-induced cardiac dysfunction in a mouse model.…”