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49721
Amblyomin-X, a recombinant Kunitz-type inhibitor, regulates cell adhesion and migration of human tumor cells
Published 2020“…In the present report, we provide a mechanistic insight to these antitumor effects, this is, Amblyomin-X modulates Rho-GTPases and uPAR signaling, and reduces the release of MMPs, leading to disruption of the actin cytoskeleton and decreased cell migration of tumor cell lines. …”
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49722
Trapping Lithium into Hollow Silica Microspheres with a Carbon Nanotube Core for Dendrite-Free Lithium Metal Anodes
Published 2017“…Li metal anodes, which have attracted much attention for their high specific capacity and low redox potential, face a great challenge in realizing their practical application. …”
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49723
The intrinsic fluctuations follow a binomial distribution and can maximize their variance away from the threshold of the response curve.
Published 2013“…<p>(<b>A</b>) Comparison between Eq. (5) (in dark blue) and numerical simulation (red line). …”
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49724
Table_1_Identification and characterization of a novel gene involved in glandular trichome development in Nepeta tenuifolia.XLSX
Published 2022“…Virus-induced gene silencing of NtMIXTA1 resulted in lower PGT density, a significant reduction in monoterpene concentration, and the decreased expression of genes related to monoterpene biosynthesis. …”
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49725
Theta Burst Stimulation of the Cerebellum Modifies the TMS-Evoked N100 Potential, a Marker of GABA Inhibition
Published 2015“…<div><p>Theta burst stimulation (TBS) of the cerebellum, a potential therapy for neurological disease, can modulate corticospinal excitability via the dentato-thalamo-cortical pathway, but it is uncertain whether its effects are mediated via inhibitory or facilitatory networks. …”
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49726
Methylophiopogonanone A, an Ophiopogon homoisoflavonoid, alleviates high-fat diet-induced hyperlipidemia: assessment of its potential mechanism
Published 2020“…In HFD-induced rats, pretreatment with MO-A decreased the body weight gain and reduced serum and hepatic lipid levels. …”
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49727
Image3_m6A Modification Involves in Enriched Environment-Induced Neurogenesis and Cognition Enhancement.TIFF
Published 2022“…Notably, EE exposure decreased the protein level of m<sup>6</sup>A eraser Fto, but did not affect the protein level of m<sup>6</sup>A writers METTL3 and METTL14. …”
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49728
Supplementary Material for: Evaluation of a novel combination therapy, based on trifluridine/tipiracil and fruquintinib, against colorectal cancer
Published 2023“…Its major mechanism of action is the dysfunction of tumoral DNA including DNA strand breaks and decreased replication. Fruquintinib (ELUNATE®) is a novel kinase inhibitor that selectively inhibits the vascular endothelial growth factor receptor-1, -2, and -3. …”
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49729
Datasheet2_Case report: Muscle involvement in a Chinese patient with TRNT1-related disorder.pdf
Published 2023“…Whole-exome sequencing revealed compound heterozygous variants of the TRNT1 gene, c.443C > T (p.Ala148Val) and c.692C > G (p.Ala231Gly), in the patient. Western blot showed a decreased expression of TRNT1 and cytochrome c oxidase subunit IV (COX IV) in the skeletal muscle of the patient. …”
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49730
Table2_m6A Modification Involves in Enriched Environment-Induced Neurogenesis and Cognition Enhancement.XLSX
Published 2022“…Notably, EE exposure decreased the protein level of m<sup>6</sup>A eraser Fto, but did not affect the protein level of m<sup>6</sup>A writers METTL3 and METTL14. …”
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49731
Data for: Drought and temperature stresses impact pollen production and autonomous selfing in a California wildflower, Collinsia heterophylla
Published 2025“…In plants experiencing abiotic stress, an increase in autonomous self-pollination was facilitated through a compromise in herkogamy, a sexual interference mechanism to promote cross-pollination. …”
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49732
Table_6_Identification and characterization of a novel gene involved in glandular trichome development in Nepeta tenuifolia.XLSX
Published 2022“…Virus-induced gene silencing of NtMIXTA1 resulted in lower PGT density, a significant reduction in monoterpene concentration, and the decreased expression of genes related to monoterpene biosynthesis. …”
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49733
Image3_A pan-cancer analysis of the expression and molecular mechanism of DHX9 in human cancers.JPEG
Published 2023“…DExH-box helicase 9 (DHX9) plays a central role in many cellular processes but its expression pattern and prognostic value in most types of cancer remain unclear. …”
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49734
Data_Sheet_1_Psychological Antecedents of the Intention to Open the Windows at Home and Exposure to a Ventilation Recommendation.docx
Published 2022“…Objective<p>The psychological antecedents of the intention to open the windows at home were explored through the Theory of Planned Behavior (TPB), supplemented with Habits regarding the behavior and contextual factors.</p>Design<p>A four-treatment design compared the effect of an exposure to a recommendation about home ventilation and the effect of one’s own awareness odors (negative vs. positive) as a manipulated variable. …”
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49735
A Functional Neuroimaging Study of Sound Localization: Visual Cortex Activity Predicts Performance in Early-Blind Individuals
Published 2013“…During binaural sound localization, a sighted control group showed decreased cerebral blood flow in the occipital lobe, which was not seen in early-blind individuals. …”
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49736
Evaluation of Silicon Nitride as a Substrate for Culture of PC12 Cells: An Interfacial Model for Functional Studies in Neurons
Published 2014“…We found that coating silicon nitride with poly-L-lysine increased surface hydrophilicity and that exposing this coated surface to an extracellular aqueous environment gradually decreased its roughness. When PC12 cells were cultured on a coated silicon nitride surface, adhesion and spreading were facilitated, and the cells showed enhanced morphological differentiation compared to those cultured on a plastic culture dish<b>.…”
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49737
Effects of a Video Game-Based Intervention on the Attention and Functional Independence of Older Adults after Cerebrovascular Accident
Published 2022“…During the colorful trails tests´ the time reduced 330,5±140,8 second at the evaluation, from 259,4±112,5 second the reevaluation (p=0,039), for more, the psychologist professional interference needs decreases from 0,8±0,5 to 0,4±0,3 (p=0,036). The Functional Independence average obtained at first was a score of 102,3 ± 23,4 (modified dependence) and at the reevaluation a score of 107±18,6 (modified independence) (p=0,044). …”
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49738
Population Genetic Diversity and Structure of a Naturally Isolated Plant Species, <em>Rhodiola dumulosa</em> (Crassulaceae)
Published 2011“…<div><h3>Aims</h3><p><em>Rhodiola dumulosa</em> (Crassulaceae) is a perennial diploid species found in high-montane areas. …”
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49739
Image1_A Polysaccharide From Eupolyphaga sinensis Walker With Anti-HBV Activities In Vitro and In Vivo.pdf
Published 2022“…The results showed that ESPS significantly inhibited the production of HBsAg, HBeAg, and HBV DNA in the supernatants of HepG2.2.15 in a dose-dependent manner; HBV RNA and core protein expression were also decreased by ESPS. …”
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49740
Table 2_Mortality and trends of pulmonary arterial hypertension, 1990–2021: a population-based study.docx
Published 2025“…Background<p>Pulmonary arterial hypertension (PAH) is a progressive disease associated with high fatality rate. …”